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In vitro NMR investigation of controlled single and repeated isoflurane anesthesiaHolzmuller, P... ...Immobilization of laboratory animals is a basic requirement for experimental in vivo NMR measurements. The effect of single and repeated isoflurane anesthesia on proton NMR relaxation times T1 and T2 ... in rat liver was studied. Furthermore, physiological monitoring was performed to evaluate the influence of isoflurane anesthesia (up to 2 hr) on biological parameters. Neither singlenor repeated isoflurane application over the observed time produce relevant alterations of physiological parameters or relaxation times, comparedwith untreated control groups. Therefore, we conclude that isoflurane anesthesia is appropriate for in vivo NMR investigations, especially of the liver.Vir: Magnetic resonance in medicine. - ISSN 0740-3194 (Let. 10, št. 3, 1992, str. 393-400)Vrsta gradiva - članek, sestavni delLeto - 1992Jezik - angleškiCOBISS.SI-ID - 7551193
Avtor
Holzmuller, P... |
Moser, E... |
Werba, A... |
Markis, E... M. |
Gomišček, Gregor
Teme
Anesthesia |
Isoflurane |
Administration and dosage |
Nuclear magnetic resonance |
Carbon dioxide |
Blood |
Hemodynamics |
Drug effects |
Isoflurane |
Pharmacology |
Liver |
Chemistry |
Cytology |
Drug effects |
Rats |
Rats, inbred strains |
Respiration |
Drug effects
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Gomišček, Gregor | 18038 |
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