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A multinational case-control study of cardiovascular disease and steroid hormone contraceptives : description and validation of methodsDebert-Ribeiro, Myriam ...A hospital-based, case-control study of the association between current usage of oral contraceptives and first-time cases of acute myocardial infarction, stroke, or a venous thromboembolic event ... (deep vein thrombosis or pulmonary embolus) was carried out in 17 countries from four regions (Africa, Asia, Europe, and Latin America). A total of 3792 cases and 10,281 hospitalised controls matched for age were recruited during a 4-year period, ending in June1993. The study was designed to have sufficient power to detect a relativerisk of 2 for developing each of the three study diseases, associated with current oral contraceptive use in each of the four regions, with the exception of acute myocardial infarction (for which all non-European regions were to be combined) and for venous thromboembolic events in Asia, where thesedisorders are rare. This report describes the background, pilot study, methods, and the analyses carried out to validate the methods used in the study.Vir: Journal of Clinical Epidemiology. - ISSN 0895-4356 (Let. 48, št. 12, 1995, str. 1513-1547)Vrsta gradiva - članek, sestavni delLeto - 1995Jezik - angleškiCOBISS.SI-ID - 7658969
Avtor
Debert-Ribeiro, Myriam |
Medina, Ernesto |
Artigas, Jorge |
He, Shen |
Hui, Zhong Yu |
De-Wei, Zhang |
Rojas, Oscar |
Vessey, Martin |
Heinemann, Lothar |
Kožuh-Novak, Mateja
Teme
Cerebrovascular disorders |
Chemically induced |
Contraceptives, oral, hormonal |
Adverse effects |
Epidemiologic methods |
Myocardial infarction |
Chemically induced |
Thrombophlebitis |
Chemically induced |
Acute disease |
Adult |
Case-control studies |
Cerebrovascular disorders |
Epidemiology |
Myocardial infarction |
Epidemiology |
Pilot projects |
Reproducibility of results |
Risk factors |
Thrombophlebitis |
Epidemiology |
World health organization
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