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  • Safety and efficacy of Diarr-Stop S Plus© (Na2EDTA, tannin-rich extract of Castanea sativa, thyme oil and oregano oil) as a feed additive for pigs for fattening [Elektronski vir] : EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
    Aquilina, Gabriele ...
    Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and ... eficacy of Diarr-Stop S Plus, a mixture of sodium salt of ethylene diamine tetra acetic acid (Na2EDTA),a tannin-rich extract of Castanea sativa, thyme oil and ore gano oil. The additive is intended for usewith pigs for fattening at a recom mended dose of 1,000 mg/kg feed to reduce the incidence of dysentery caused by Brachyspira hyodysenteriae and so improve performance. The additive isconsidered safe for pigs for fattening at the recommended dose of 1,000 mg/kg feed. None of the active constituents of Diarr-Stop S Plus raised safety concerns for consumers when considered individually and at the concentrations delivered to feed using the recommended dose. As no interactions between constituents impacting on consumer safety are expected, the use of Diarr-Stop SPlus in feed for pigs for fattening is considered safe for consumers without a with drawal period. The additive should be considered as a skin and eye irritant, but the FEEDAP Panel could not conclude on the potential for dermal sensitisation. Because of the particle size, exposure of users by inhalation is considered unlikely. In the absence of appropriate data on the ecotoxicological effects of Na2EDTA, the assessment of risk for terrestrial and aquatic compartments cannot be completed. None of the submitted efficacy studies, all based on observations on commercial pre mises, comply with the minimum requirements for an experimental design for the demonstration of efficacy. Consequently, the FEEDAPPanel is unable to conclude on the efficacy of the additive Diarr-Stop S Plus when used in feed for pigs for fattening.
    Vir: EFSA journal [Elektronski vir]. - ISSN 1831-4732 (Vol. 14, issue 5, 2016, 15 str.)
    Vrsta gradiva - e-članek
    Leto - 2016
    Jezik - angleški
    COBISS.SI-ID - 88538625

    Povezava(-e):

    https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2016.4472
    DOI

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