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Mumps and mumps vaccine : a global reviewGalazka, A... M. ; Robertson, S... E. ; Kraigher, Alenka, 1950-Mumps is an acute infectious disease caused by a paramyxovirus. Although the disease is usually mild, up to 10% of patients can develop aseptic meningitis;a less common but more serious complication ... is encephalitis, which can result in death or disability. Permanent deafness, orchitis, and pancreatitis are other untoward effects of mumps. Based on data reported to WHO up to April 1998, mumps vaccine is rountinely used by national immunization programmes in 82 countries/areas: 23 (92%) of 25 developed countries, 19 (86%) of 22 countries with economies in transition (mainly the newly Independent States of the former Soviet Union), and 40 (24%) of 168 developing countries. Countries that have achieved high coverage have shown a rapid decline in mumps morbidity. Furthermore, in many of these countries, mumps-associated encephalitis and deafness have nearly vanished. This review considers the disease burden due to mumps; summarizes studies on the immunogenicity, efficacy, and safety of different strains of mumps vaccine; and highlights lessons learned about implementing mumps immunization in different countries. Countries already using mumps vaccine should monitor immunization coverage and establish routine mumps surveillance with investigation of outbreaks. Where mumps is targeted for elimination, countriesneed to add a second dose of mumps vaccine for children, keeping in mind that the disease may still occur in susceptible adults.Vir: Bulletin of the World Health Organization = Bulletin de l'Organisation mondiale de la santé. - ISSN 0042-9686 (Letn. 77, št. 1, 1999, str. 3-14)Vrsta gradiva - članek, sestavni delLeto - 1999Jezik - angleškiCOBISS.SI-ID - 9467097
Avtor
Galazka, A... M. |
Robertson, S... E. |
Kraigher, Alenka, 1950-
Teme
Mumps |
Mumps vaccine |
Mumps virus |
Paramyxovirus infections |
Parotid diseases |
Parotitis |
Immunization programs |
Statistics and numerical data |
Vaccination |
Statistics and numerical data |
Epidemiology |
Central nervous system diseases |
Epidemiology |
Etiology
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