FF, Osrednja humanistična knjižnica, Ljubljana (FFLJ)
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Detecting subtle cognitive impairment in patients with Parkinson’s disease and normal cognition [Elektronski vir] : a novel cognitive control challenge task (C3T)Resnik Robida, Karmen, 1988- ...: Patients with Parkinson’s disease (PD) often show early deficits in cognitive control, with primary difficulties in flexibility and relatively intact stable representations. The aim of our study ... was to assess executive function using an ecologically valid approach that combines measures of stability and flexibility. Fourteen patients without cognitive deficits and sixteen comparable control subjects completed a standardized neuropsychological test battery and a newly developed cognitive control challenge task (C3T). We found that the accuracy of C3T performance decreased with age in healthy participants and remained impaired in PD patients regardless of age. In addition, PD patients showed significantly lower overall performance for cognitive control tasks than healthy controls, even when they scored in the normal range on standardized neuropsychological tests. PD Patients responded significantly faster than healthy control subjects regarding flexible cognitive control tasks due to their impulsivity. Correlations showed that the C3T task targets multiple cognitive systems, including working memory, inhibition, and task switching, providing a reliable measure of complex cognitive control. C3T could be a valuable tool for characterizing cognitive deficits associated with PD and appears to be a more sensitive measure than standardized neuropsychological tests. A different assessment approach could potentially detect early signs of the disease and identify opportunities for early intervention with neuroprotective therapies.Vir: Brain sciences [Elektronski vir]. - ISSN 2076-3425 (Vol. 13, iss. 6, 2023, str. 1-10)Vrsta gradiva - e-članek ; neleposlovje za odrasleLeto - 2023Jezik - angleškiCOBISS.SI-ID - 156747267
Avtor
Resnik Robida, Karmen, 1988- |
Politakis, Vida Ana |
Oblak, Aleš |
Slana Ozimič, Anka |
Burger, Helena |
Pirtošek, Zvezdan, 1956- |
Bon, Jurij
Teme
kognitivni nadzor |
mere izvršilnih funkcij |
Parkinsonova bolezen |
preklapljanje med nalogami |
cognitive control |
executive functioning measures |
Parkinson’s disease |
task switching
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Resnik Robida, Karmen, 1988- | ![]() |
Politakis, Vida Ana | 37430 |
Oblak, Aleš | 55036 |
Slana Ozimič, Anka | 36162 |
Burger, Helena | 14962 |
Pirtošek, Zvezdan, 1956- | 05380 |
Bon, Jurij | 33621 |
Vir: Osebne bibliografije
in: SICRIS
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