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  • Farmakoepidemiološki in farmakoekonomski vidiki zdravljenja duševnih bolezni = Pharmacoepidemiologic and pharmacoeconomic aspects of mental illness treatment
    Drinovec, Jože ; Ivanuša, Marijan, 1966- ; Pečar, Milka
    Well-conducted prospective studies investigating drug therapy in patients withmental disorders have only become available in the past ten years. In thismedical area, the criteria for evaluating drug ... efficacy are much more complicated as those used in somatic diseases. The consumption of the most important drug groups with CNS effects, especially antidepressants, is rapidlyincreasing worldwide as well as in our country. The authors of this article conducted an investigation into the most common mental disorders: anxiety disorders, depressive disorders and schizophrenia. Anxiety disorders are of common occurrence; they may be short lasting and caused by a number of drugs. Manifestations of anxiety are interlaced with symptoms of depression. In the past anxiety disorders were most often treated with benzodiazepines, while in the last decade also antidepressants have been introduced into therapy. One out of 8 people experiences depressive disorders during his lifetime. A severe depressive disorder may lead to a suicidal action and is associated with other mental and somatic diseases. The most commonly prescribed drug groups used for the management of depressive disorders includetricyclic antidepressants and serotonin re-uptake inhibitors. While similar efficacy has been demonstrated for both groups of drugs, the group of serotonin re-uptake inhibitors has been shown to be associated with better tolerability. Schizofrenia afflicts only 1% of the population, but it is associated with a high degree of debilitation of the patient and an unproportionately great social impact. Schizophrenia requires frequent and long-lasting hospitalization: it reduces the patients normal functioning in his environment, his productivity and decreases his quality of life. The cost of drug therapy accounts for no more than 5% of the total expenses involved inthe treatment of schizophrenia.
    Vir: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 51, pos. št., maj 2000, str. 215-221)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - slovenski
    COBISS.SI-ID - 11839449

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