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  • Farmakoepidemiološka analiza porabe antidepresivov v Sloveniji = Pharmacoepidemiologic analysis of the use of antidepressants in Slovenia
    Primožič, Stanislav ...
    The use of antidepressants (AD) according to the ATC classification was surveyed along with monitoring of particular drugs within the therapeutic-pharmacologic-chemical subgroups. In ambulatory care, ... the most utilized are the selective serotonin reuptake inhibitors which show a positiveusage trend. The class of tricyclic antidepressants whose use nowadaysis decreasing, is taking the second place. The use of this class has not changed in terms of DDD/1000 inhabitants/day, however its fraction, relative to the overall use of antidepressants, has diminished due to the increase of the latter. Lower use is observed in the "other antidepressants" group and in the reversible monoamino oxidase type A inhibitors class.Among psychiatric hospitals Begunje, Idrija and (Ljubljana) Polje we found no significant differences in the pharmacotherapeutics of depression. Moreover, the majority of the 9,3 DDD/1000 inhabitants/day were prescribed in the ambulatory care, and only 0,4 DDD/1000 inhabitants/day to the patients in hospitals. This finding is in agreement with the current trends in international pharmacotherapy of psychiatric disorders. Obtained projection ofthe overall Ad use in Slovenia in 1999 was substantially lower than the use in Norway in the same year, namely 9,7:36,1 DDD/1000 inhabitants/day. Differences could be interpreted in several ways, however, we believe that themain contributing factor is the underdiagnosing of depression in Slovenia. In order to perform national pharmacoepidemiologic analyses in this country, acentralized hospital and self-medication drug utilization system should be implemented along with the existing ambulatory care drug surveillance system.
    Vir: Zdravstveno varstvo : Slovenian journal of public health. - ISSN 0351-0026 (Letn. 40, št. 1/2, 2001, str. 81-86)
    Vrsta gradiva - članek, sestavni del
    Leto - 2001
    Jezik - slovenski
    COBISS.SI-ID - 12999641

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