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  • Preživetje otrok in mladostnikov s solidnimi tumorji v Sloveniji v obdobju 1990-2000 = Survival of children and adolescents with solid tumours in Slovenia in the period 1990-2000
    Velenšek Prestor, Veronika ; Jazbec, Janez, 1962-
    A retrospective clinical analysis was performed to evaluate the outcome in 184children with different solid tumours and Hodgkin lymphoma treated at the Department of Paediatric Oncology and ... Haematology in Ljubljana between 1990 - 2000. Thirty-seven of these patients (pts) had Wilms tumour, 31 pts had neuroblastoma, 25 pts had rhabdomyosarcoma (RMS), 18 pts had Ewing sarcoma /PNETof bone, 16 pts had osteosarcoma and 57 pts had Hodgkin disease. They were 17 days to 18 years old at diagnosis. Patients were treated according to the diagnosis and stage of the disease with chemotherapy, surgery and radiotherapy. Nine patients also underwent bone marrow transplantation. The observation period was from the time of diagnosis until the last follow-up or until death from any cause. The follow-up time was 0.25-12 years. Event-free survival rate (EFS) and the overall survival rate (OS) were estimated using the Kaplan-Maier method. The results of Kaplan-Maier analysis were as follows:the 2-year OS for the entire group of pts with Wilms tumour was 84 % (EFS 80 %), in stage 1 91 %, in stage 2 80 %, in stage 3 60 %, in stage 5 66 %. The 2-year OS for the entire group of pts with neuroblastoma was 61 % (EFS 54 %), for stage 1 and 2 100 %, stage 3 50 %, stage 4 21 %. The 2-year OS for the entire group of pts with RMS was 75 % (EFS 64 %), for stage 1 90 %, for stage 2 85 %, for stage 3 50 %, for stage 4 40 %. The 2year OS for all pts with Ewing sarcoma /PNET of bone was 64 % (EFS 45 %), for pts with PNET 67 %, for pts with Ewing sarcoma 27 %. The 2-year OS for all pts with osteosarcoma was 81 % (EFS 53 %). The 2-year OS for all pts with Hodgkin disease was 96 % (EFS 93 %), the 2-year OS in stage lis 100 %, in stage 2 96 %, in stage 3 93 %, in stage 4 53 %. A high overall survival outcome was obtained for patients with Hodgkin disease and Wilms tumour. (Abstract truncated at 2000 characters).
    Vir: Slovenska pediatrija : revija Združenja pediatrov Slovenije in Združenja specialistov šolske in visokošolske medicine Slovenije. - ISSN 1318-4423 (Letn. 9, [št.] 2/3, 2002, str. 94-99)
    Vrsta gradiva - članek, sestavni del
    Leto - 2002
    Jezik - slovenski
    COBISS.SI-ID - 15513817

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