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  • Spremljanje občutljivosti izolatov Streptococcus pyogenes in Streptococcus pneumoniae, osamljenih na Inštitutu za mikrobiologijo in imunologijo Medicinske fakultete v Ljubljani od leta 1994 do 2002 = Monitoring of antimicrobial susceptibility of Streptococcus pyogenes and Streptococcus pneumoniae isolated at the Institute of microbiology and immunology of the Ljubljana Medical faculty between 1994 and 2002
    Seme, Katja, 1966- ; Müller-Premru, Manica
    Streptococcus pneumoniae and Streptococcus pyogenes are important respiratory pathogens. They have been known to develop resistance to common therapeutic options relatively rapidly. The objective of ... this paper is to present the macrolide susceptibility rates for S. pyogenes and S. prieumontae isolated from respiratory tract specimens at the Institute of Microbiology and Immunology of the Ljubljana Medical Faculty from 1994 to 2002 in order to establish year-to-year changes in susceptibility rates for other antibiotics and to compare the susceptibility rates of noninvasive and invasive pneumococci. The erythromycin resistance rate of S. pyogenes increased from 4.2% in 1995 to 7.4% in 1999. The rate of macrolide resistant S. pyogenes has remained relatively stable after 1999 and was between 5.4% in 2001 and 7.0% in2002. All S. pyogenes isolates continued to be susceptible to penicillin, cefotaxime and vancomycin, while the clindamycin susceptibility rate was a bithigher than that for macrolides. The erythromycin resistance rate of pneumococci isolated from the upper respiratory tract was on a constant increase from one year to the next and rose from 0.4% in 1995 to 22.8% in 2002. The penicillin resistance rate of noninvasive S. pneumoniae increased gradually, with the exception of a minor decrease in 2000, and rose from 17.7%in 1998 to 30.8% in 2002. The resistance rate for all other routinely tested antibiotics (macrolides, clindamycin, trimethoprim-sulfamethoxazole andtetracycline) with the exception of vancomycin was significantly higher among penicillin resistant pneumococci. The penicillin resistance rate of invasive pneumococci was lower during the entire studied period and increased from 5.9% in 1998 to 17.1% in 2000. The trend of increase in penicillin resistance among invasive pneumococci was less obvious than among noninvasive isolates.
    Vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 42, supl. 1, mar. 2003, str. 11-21)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2003
    Jezik - slovenski
    COBISS.SI-ID - 16359641

vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 42, supl. 1, mar. 2003, str. 11-21)

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