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  • Hemostaza pri glodalcih - povezava s predkliničnimi raziskavami novih antitrombotikov
    Peternel, Luka ; Stegnar, Mojca
    The most commonly used laboratory animals belong to the animal order of rodents. Above all mice and rats are, because of their small size and exceptional reproductive capacity, the most frequently ... used laboratory animalsin aplicative as well as in basic science. The extensive knowledge of the mouse genome has made the manipulation of the mouse genom a very useful tool for recognition of genes known to be associated with human disease states. In order to interpret correctly the results of experiments with laboratory animals it is important that the studied biological system is well defined, so that its similarities to, and differences from the human system can be appreciated. The focus of this review is the biological system of hemostasis and its comparison with human system. Additionaly, a special attention was payed on the correct selection of animal species for preclinicalstudies of novel antithrombotics.
    Vir: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 55, št. 3, okt. 2004, str. 491-499)
    Vrsta gradiva - članek, sestavni del
    Leto - 2004
    Jezik - slovenski
    COBISS.SI-ID - 18765273

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