Narodna in univerzitetna knjižnica, Ljubljana (NUK)
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Vpliv možganske okvare na različnih mestih na potek infantilnih spazmov : doktorska disertacijaRener-Primec, ZvonkaBackground. Infantile spasms (IS) as an epileptic syndrome generally associated with the first year of life and a specific EEG pattern - hypsarrhythmia still represent one of the most serious forms ... of epilepsy in early childhood. The prognosis is mostly unfavourable and the, final outcome of the disease is often mental retardation and the development of resistant epilepsy. The etiology is heterogeneous and significantly influences the future course of the disease, which is most unfavourable in cases of symptomatic etiology associated with prior encephalopathy. Symptomatic causes include various types of brain damage which may lead to the development of IS and, due to their epileptic nature, unsuccessful treatment and the later development of resistant epilepsy. The objectives of the study were to identify the types and localization of cortical brain lesions in children withIS, compare the focal signs in the clinical picture and EEG, and evaluate their coincidence with the location of brain damage in the CTžMR images. Another objective of the study was to determine the correlation between the location of the cortical lesion and age at the onset of IS, the impact of long-lasting hypsarrhythmia on the cognitive outcome, and to assess the effectiveness of treatment with steroids compared to other antiepileptic drugs. Patients and Methods. The study included 48 patients who, due to first diagnosed IS, were admitted to the University Paediatric Hospital in the period from lst January 1985 to 31st December 1995. Data on risk factors, age at the onset of IS, neurological and development status at the onset of the disease, the form of IS, and the presence of focal signs or partial seizures were retrospectively collected from the medical records. The type of hypsarrhythmia and the presence of focal or regional epileptifom activity andžor slow activity were determined on the basis of EEG reports. (Abstract truncated at 2000 characters).Vrsta gradiva - disertacija ; neleposlovje za odrasleZaložništvo in izdelava - Ljubljana : [Z. Rener Primec], 2002Jezik - slovenskiCOBISS.SI-ID - 2405652
Avtor
Rener-Primec, Zvonka
Drugi avtorji
Vodušek, David B.
Teme
Možganska skorja |
Okvare |
Disertacije |
Infantilni spazmi |
Etiologija |
Disertacije |
otroci |
epilepsija
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Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Rener-Primec, Zvonka | 07530 |
Vodušek, David B. | 07476 |
Vir: Osebne bibliografije
in: SICRIS
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