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  • Contact hypersensitivity to selected excipients of dermatological topical preparations anf cosmetics in patients with chronic eczema
    Dastychová, Eliška ; Nečas, Miroslav ; Vaškù, Vladimir
    Objective: 1) Assessment of the frequency of contact sensitization to selectedexcipients of dermatological topical preparations and cosmetics in patients with chronic eczema. 2) Detection of the ... sources of sensitization. Methods: 1,927 patients with chronic eczema (mean age 44.3 years, 601 males, 1,326 females) were patch tested with selected excipients. Results: The main rates of sensitization observed were: thiomersal 11.3%, wool alcohols 4.0%, phenylmercuric acetate 3.1%, formaldehyde 2.5%, dodecyl gallate 2.0%, Bronopol1.9%, dibromodicyanobutane/phenoxyethanol (1:4) 1.7%, chloracetamide 1.6%, chlorhexidine digluconate 1.5%, Kathon CG 1.4%, parabens 1.1%, diazolidinyl urea 0.9%, imidazolidinyl urea 0.7%, benzalkonium chloride 0.7%, and Quaternium-15 (quaternary ammonium salt) 0.7%. Conclusion: The rate of sensitization to the excipients included in dermatological topical preparations and cosmetics in patients with chronic eczema is significant. Complete information on all the ingredients is necessary.
    Vir: Acta dermatovenerologica Alpina, Panonica et Adriatica. - ISSN 1318-4458 (Vol. 17, no. 2, jun. 2008, str. 61-68)
    Vrsta gradiva - članek, sestavni del
    Leto - 2008
    Jezik - angleški
    COBISS.SI-ID - 24540377

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    Digitalna knjižnica Slovenije - dLib.si

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