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  • Vpliv alkoholnih pijač, prehrane in zdravil na tveganje zbolevanja za jetrno cirozo = Influence of alcohol consumption, diet and drugs on the risk for liver cirrhosis occurrence
    Grobovšek-Opara, Sonja, 1946- ; Kožuh-Novak, Mateja ; Križman, Igor, 1935-
    Background. Our research is a case-control study where the influence of alcohol drinking, diet and drugs consumption on the risk of liver cirrhosis occurrence in Slovenia was investigated. Methods. ... 182 in-patients were included in the study, who were for the first time treated for liver cirrhosison the internal disease wards of the Slovenian hospitals in the period between January to July 1995. Liver cirrhosis was diagnosed on the basis of clinical status, laboratory tests and liver ultrasound examination. Control persons were taken from the Population registry of the Statistical Offic of the Republic of Slovenia, and they were adjusted to the patients according to gender, age and dwelling place. We searched for two control persons for each patient. The data were gathered in personal interviews. Patients were interviewed in hospitals and control persons at their homes. In the statistical analysis of data the univariate and multivariate conditional logistic regression was used. Results. We found out that consuming alcohol andhepatoxic drugs increased the risk for liver cirrhosis, while the appropriate diet had a protective effect. The association between the alcohol drinking and liver cirrhosis depends on the daily amount of consumed alcohol and the duration of drinking; the risk for liver cirrhosis was growing with increasing cumulative amount of alcohol. Calculated odds rations were high, confirming the causal relatioship between alcohol drinking and liver cirrhosisoccurrence. Alcohol drinkers had 7.3-times greater risk for liver cirrhosis appearance in comparison with non-drinkers. The border for the risk for liver cirrhosis to increase significantly was 250 kg of pure alcohol consumed during life-time or average daily intake of 20 g of pure alchol.(Abstract truncated at 2000 characters)
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 67, št. 12, dec. 1998, str. 727-732)
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 8151001

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