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zadetkov: 12
1.
  • A flow-cytometry-based assa... A flow-cytometry-based assay to assess granule exocytosis and GZB delivery by human CD8 T cells and NK cells
    Li, Tong; Smith, Mindy; Abdussamad, Maryam ... STAR protocols, 03/2023, Letnik: 4, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    CD8 T and NK cells mediate killing by delivery of perforin and granzyme B (GZB) stored in lysosome-like granules. We present a flow-cytometry-based protocol combined with a redirected killing assay ...
Celotno besedilo
Dostopno za: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
2.
  • SARS-CoV-2 infection reduce... SARS-CoV-2 infection reduces the frequencies of angiogenic CD4 and CD8 T cells (Tang)
    AbdusSamad, Maryam; Li, Tong; Timpone, Joseph ... The Journal of immunology (1950), 05/2022, Letnik: 208, Številka: 1_Supplement
    Journal Article
    Recenzirano

    Abstract SARS-CoV-2 is one of the leading causes of mortality worldwide with rising death toll over 5.4 million. The severe presentation of the disease is associated with systemic inflammation, ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK
3.
  • Abstract 2501: Combination ... Abstract 2501: Combination therapy with mebendazole, trametinib and metformin eliminates recalcitrant NRASQ61K melanoma cells
    AbdusSamad, Maryam; Gaur, Anirudh; Simbulan-Rosenthal, Cynthia M. ... Cancer research (Chicago, Ill.), 07/2016, Letnik: 76, Številka: 14_Supplement
    Journal Article
    Recenzirano

    Abstract Melanoma is an aggressive and lethal form of cancer with increasing incidence worldwide. In recent years, the FDA approved several promising treatments for malignant melanoma. However, ...
Celotno besedilo
Dostopno za: CMK, UL
4.
  • A genome-wide association s... A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes
    Hanson, Robert L; Muller, Yunhua L; Kobes, Sayuko ... Diabetes (New York, N.Y.), 01/2014, Letnik: 63, Številka: 1
    Journal Article
    Recenzirano
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    Most genetic variants associated with type 2 diabetes mellitus (T2DM) have been identified through genome-wide association studies (GWASs) in Europeans. The current study reports a GWAS for ...
Celotno besedilo
Dostopno za: CMK, UL

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5.
  • Greater Impact of Melanocor... Greater Impact of Melanocortin-4 Receptor Deficiency on Rates of Growth and Risk of Type 2 Diabetes During Childhood Compared With Adulthood in Pima Indians
    THEARLE, Marie S; MULLER, Yunhua L; HANSON, Robert L ... Diabetes, 01/2012, Letnik: 61, Številka: 1
    Journal Article
    Recenzirano
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    Features of melanocortin-4 receptor (MC4R) deficiency have been observed to be more pronounced in childhood. Longitudinal data from a population-based study were used to separate the phenotypic ...
Celotno besedilo
Dostopno za: CMK, UL

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6.
  • Abstract 4224: CD133 knockd... Abstract 4224: CD133 knockdown sensitizes melanoma to kinase inhibitors
    AbdusSamad, Maryam; Gaur, Anirudh; Zhou, Hengbo ... Cancer research (Chicago, Ill.), 08/2015, Letnik: 75, Številka: 15_Supplement
    Journal Article
    Recenzirano

    Abstract Melanoma is an aggressive and lethal form of cancer, responsible for 9,710 deaths in the US every year, as indicated by the Surveillance Epidemiology and End Results (SEER) program. Although ...
Celotno besedilo
Dostopno za: CMK, UL
7.
  • Abstract 3891: CD133 is ass... Abstract 3891: CD133 is associated with resistance of melanoma to multikinase inhibition
    Zhou, Hengbo; Abdussamad, Maryam; Alomari, Amani ... Cancer research (Chicago, Ill.), 10/2014, Letnik: 74, Številka: 19_Supplement
    Journal Article
    Recenzirano

    Abstract Purpose: High-risk melanoma is a lethal cancer with a high recurrence rates and variable disease-free intervals, due to tumorigenic cell populations that are resistant to treatment. Prominin ...
Celotno besedilo
Dostopno za: CMK, UL
8.
  • CD133 Is Associated with In... CD133 Is Associated with Increased Melanoma Cell Survival after Multikinase Inhibition
    Simbulan-Rosenthal, Cynthia M.; Gaur, Anirudh; Zhou, Hengbo ... Journal of oncology, 2019, Letnik: 2019
    Journal Article
    Recenzirano
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    FDA-approved kinase inhibitors are now used for melanoma, including combinations of the MEK inhibitor trametinib, and BRAF inhibitor dabrafenib for BRAFV600 mutations. NRAS-mutated cell lines are ...
Celotno besedilo
Dostopno za: FZAB, GIS, IJS, IZUM, KILJ, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK

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9.
  • A cis-eQTL in PFKFB2 is ass... A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians
    Muller, Yunhua L; Piaggi, Paolo; Hanson, Robert L ... Human molecular genetics, 05/2015, Letnik: 24, Številka: 10
    Journal Article
    Recenzirano
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    A prior genome-wide association study (GWAS) in Pima Indians identified a variant within PFKFB2 (rs17258746) associated with body mass index (BMI). PFKFB2 encodes 6-phosphofructo-2-kinase/fructose ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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10.
  • Variants associated with ty... Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP
    Nair, Anup K.; Muller, Yunhua Li; McLean, Nellie A. ... Diabetologia, 11/2014, Letnik: 57, Številka: 11
    Journal Article
    Recenzirano
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    Aim/hypothesis A recent genome-wide trans-ancestry meta-analysis identified seven new loci associated with type 2 diabetes. We assessed the replication of the seven lead single nucleotide ...
Celotno besedilo
Dostopno za: EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ

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zadetkov: 12

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