This study aimed to investigate the ion pair association values and association parameters of nano MnSO4 in water and methanol-water mixtures (20 % and 40 % methanol by mass percentage) at varying ...temperatures (298.15, 303.15, 308.15, and 313.15 K) using the conductometric technique. Additionally, the parameters for complex formation between nano MnSO4 and glycylglycine as a ligand were determined. The focus was on elucidating the thermodynamic formation parameters for the nano Mn2+-glycylglycine interaction, with particular emphasis on comparing the 1: 1 and 1: 2 (M: L) complexes to understand the complexation behavior more comprehensively. The results indicated that the complexation process was spontaneous, as evidenced by negative ΔGf (formation free energy change) values, which increased with temperature, highlighting the enhanced spontaneity of the process. The findings provide valuable insights into designing new materials and procedures by enhancing our understanding of the complexation behavior of nano MnSO4 with ligands like glycylglycine, thus contributing to advancements in various applications such as chemical synthesis, medicines, and environmental remediation. By elucidating the thermodynamic aspects of these interactions, the study aimed to provide valuable information that could be utilized in practical applications and further research endeavors.
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The association and thermodynamic association parameters for CdBr2 were determined by the conductometric method in pure water and in a mixture of water–ethanol (0.30 mass fraction of ethanol) at ...different temperatures. The values of ion pair association was also calculated and found that CdBr2 in ceftazidime drug has greater values compared to that in the absence of ceftazidime. Also, the complex formation constants and thermodynamic parameters for complex formation between CdBr2 with ceftazidime as a ligand were also determined by the conductometric method. From the interaction of CdBr2 with ceftazidime, two stoichiometric complexes were obtained 1:1 and 1:2. The complex K f and ΔG f are greater in the case of 1:1 than that of 1:2 (CdBr2/ceftazidime) complexes in 0% ethanol and in 30% ethanol solvents indicating easier complex formation. The formation constants decreased with increased temperature. The negative values of ΔG f for complexation indicate the spontaneity of the complex formation process and that the spontaneity increased with temperature. The negative values of ΔH f show the exothermic nature of the complexation and indicate that the complexation processes are more favored at low temperatures. The ΔS f values for the complexation are positive, confirming that the complex formation is entropically favorable. Significance of the study is to give a lot of data which can be easily obtained for following the very toxic heavy metal cadmium ions.
This study investigated the physicochemical properties of the interaction of indomethacin and copper chloride using the electrical conductance measurement in methanol, ethanol, and their binary ...mixture with water at room temperature (298.15 K), to determine the solvation behavior, redox behavior, and kinetics. The association parameters were computed using the Fuoss-Hsia-Fernández-Prini and Fuoss-Shedlovsky models. The standard Gibbs energy for association (ΔGoA), Walden product (Λoηo), and hydrodynamic radii (RH) were calculated to study the interaction of indomethacin and copper chloride. On the other hand, cyclic voltammetry examines the electrochemical redox behavior of copper chloride using a gold electrode and its interactions with indomethacin. Results showed changes in peak potentials and currents density in the presence of indomethacin, indicating alterations in redox behavior and reaction rates. Overall, this research can be valuable in understanding the electrochemical properties and potential applications of indomethacin and copper chloride, as well as in developing new drugs or therapeutic agents, which could have has implications in various fields, including drug development, electrochemistry, and materials science.
•The study investigated the physicochemical properties of the interaction between indomethacin and copper chloride.•The electrical conductance in different solvents was determined to provide information about the solvation behavior, redox behavior, and kinetics of the system using the Fuoss-Shedlovsky and Fuoss-Hsia-Fernández-Prini models.•The cyclic voltammetry study revealed changes in the electrochemical redox behavior of CuCl2 in the presence of indomethacin, indicating potential applications in drug development and materials science.•Overall, this research can have significant implications in various fields.
The association parameters of both bulk and nano-CuSO₄ salts in (EtOH-H₂O) mixed solvents were estimated at room temperature (293.15K) using conductivity method by applying Fuoss-Shedlovsky ...calculation. The association parameters of nano-CuSO4 was greater than bulk CuSO₄ salt. The interaction between the cation (Cu²+) with ligand (ciprofloxacin, CFL) in (EtOH-H₂O) mixed solvents at room temperature (293.15K) was determined by the conduct metric method. The formation Gibbs free energies change (∆Gf) and transfer Gibbs free energies change (∆Gt) were increased in negative signs with increasing in EtOH content in the binary solvent. Two stoichiometric complexes 1:2 and 1:1 (M:L) are formed and the formation constant and Gibbs free energy of the formed complexes follow the order: Kf (1:1) > Kf (1:2) and ∆Gf (1:1) > ∆Gf (1:2) for (M:L) ( in negative values), which indicate more favorable formation of (1:1) complex compared with (1:2) complex. Also there are a decrease in values of Kf and ∆Gf in case of using nano-CuSO4 than that of using bulk-CuSO₄ but in small difference due to the more solvation effect in case of using nanoparticles
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•An electrochemical sensing method was developed for the estimation of strontium ions.•Explored the electrochemical behavior of strontium ions in the presence and absence of rosemary ...by the cyclic voltammetry using 18 Karat gold working electrode.•Dissolved oxygen estimation for different solutions was measured.•Molecular docking analysis suggested potential therapeutic effects of rosemary (carnosol and carnosic acid) against COVID-19.•The antibacterial activities were studied for rosemary.
This work presents an electrochemical sensing for the estimation of strontium ions by cyclic voltammetry and studies its electrochemical behavior in the presence and absence of rosemary using 18 an Karat Gold working electrode in 0.1 M KBr at 295.15 K. The potential therapeutic effects of carnosol and carnosic acid against COVID-19 were explored through molecular docking analysis, suggesting their antiviral effects. The results showed that the obtained cyclic voltammograms showed well-defined redox peaks, and the peak current was found to increase linearly with increasing strontium chloride concentration. Rosemary has been shown to have antioxidant properties, which affect the redox behavior of strontium ions, leading to changes in the peak current and potential observed. SrCl2 solution has higher oxygen solubility and is useful in various industries. Additionally, plant extract showed inhibition of the growth of Gram-positive and Gram-negative bacteria due to its antibacterial activity. Overall, this research offers a promising electrochemical approach for measuring strontium ions and, the antibacterial activity of the Rosemary extract and reveals the potential therapeutic benefits of it against COVID-19.
•Molecular thermodynamic association parameters for the bulk and nano-vanadyl sulfate were determined by the conductometry in aqueous solution at various temperatures for understanding the mechanism ...of oxidation and reduction of various vanadyl species in solutions.•From the interaction of the bulk & nano VOSO4 with Orange G, in the instance of the 1:1 complex as opposed to the 1:2 (VOSO4/Orange G) complex in water as the solvent, the estimated Kf and ΔGf were higher.•Molecular docking of VOSO4 versus 7 jwy of amino acid of covid-19 allows us to better understand the probable modes of engagement that provide more clarity on how well the molecules exert bioactivity towards the target.•VOSO4 show greater antioxidant behavior than the stander ascorbic acid with the same concentration.
Molecular thermodynamic association parameters for the bulk and nano-vanadyl sulfate were determined by the conductometry in aqueous solution at various temperatures. The thermodynamic parameters for complex formation 1:1, 1:2 (M/L) between bulk & nano vanadyl with Orange G were also determined by the conductivity measurements. From the interaction of the bulk & nano vanadyl sulfate (VOSO4) with Orange G, in the instance of the 1:1 complex as opposed to the 1:2 (VOSO4/Orange G) complex in water as the solvent, the estimated Kf and ΔGf were higher. When the temperature rises, the complex formation constants decrease. The molecular complexation's negative ΔGf values show that the production of molecular complexes is spontaneous and that it gets higher as the temperature rises. The molecular complexation is an endothermic and entropy-controlled reaction, which is supported by the negative values of ΔHf. Molecular docking of vanadyl sulfate versus 7 jwy of amino acid of covid-19 allows us to better understand the probable modes of engagement and binding affinities of the targeted molecule (vanadyl sulfate), that provide more clarity on how well the molecules exert bioactivity towards the target. The vanadyl sulfate show greater antioxidant behavior than the stander ascorbic acid with the same concentration. Also, the oxygen radicals ranging from 1.1 to 1.4 V which are reduced giving reduction peaks (broad) facilitating the use of vanadyl sulfate as a strong antioxidant solution.
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•Electrochemical properties of iron ions investigated by cyclic voltammetry using GCE.•Influence of pH, concentration and scan rate on electrochemical behavior.•Focus on the ...interaction of FeSO4 and K4Fe(CN)6 with dithizone at 293.15 K.•Assessment of scan rate, stability constants and kinetic parameters of iron-dithizone interaction.•Practical applications in detection of iron ions in biological samples and molecular docking studies.
This study aims to investigate the electrochemical characteristics and complex formation of iron ions with dithizone in various solutions including human blood at 293.15 K, using a glassy carbon working electrode. Cyclic voltammetry was employed to analyze the oxidation and reduction processes of iron ions, specifically FeSO4 and K4Fe(CN)6, and determine their stability constants. The study revealed that the electrochemical behavior of FeSO4 and K4Fe(CN)6 are complex and influenced by various factors such as pH and concentration. The (pH 4) acidic medium acts as an electrochemical catalyst, enhancing redox peak at approximately −0.2 V and showing the strongest response with maximum sensitivity. An increase in the iron ion concentration causes an increase in Ip,a/Ip,c, highlighting kinetic and adsorption challenges for analytical examination. The study also determined the scan rate and kinetic parameters of the interaction between iron and dithizone, and calculated the stability constants of the complexes formed. Additionally, the practical applications of this research in detecting iron ions in biological samples and potential molecular docking studies against viral leukemia protein will be considered.
This study aimed to investigate the ion pair association values and association parameters of nano MnSO
in water and methanol-water mixtures (20 % and 40 % methanol by mass percentage) at varying ...temperatures (298.15, 303.15, 308.15, and 313.15 K) using the conductometric technique. Additionally, the parameters for complex formation between nano MnSO
and glycylglycine as a ligand were determined. The focus was on elucidating the thermodynamic formation parameters for the nano Mn
-glycylglycine interaction, with particular emphasis on comparing the 1: 1 and 1: 2 (M: L) complexes to understand the complexation behavior more comprehensively. The results indicated that the complexation process was spontaneous, as evidenced by negative ΔG
(formation free energy change) values, which increased with temperature, highlighting the enhanced spontaneity of the process. The findings provide valuable insights into designing new materials and procedures by enhancing our understanding of the complexation behavior of nano MnSO
with ligands like glycylglycine, thus contributing to advancements in various applications such as chemical synthesis, medicines, and environmental remediation. By elucidating the thermodynamic aspects of these interactions, the study aimed to provide valuable information that could be utilized in practical applications and further research endeavors.
