This study compared the efficacy of low-level laser therapy (LLLT) versus laser acupuncture therapy (LAT) in patients with temporomandibular disorders (TMDs). In this randomized, double-blind ...clinical trial, 45 TMD patients were randomly divided into three groups. In group 1 (LLLT), a GaAlAs laser was applied on painful masticatory muscles and TMJs (810 nm, 200 mW, 30 s per point, Gaussian beam, spot size 0.28 cm
2
, 21 J/cm
2
) two times a week for 5 weeks. In group 2 (LAT), the laser was emitted bilaterally on acupuncture points (ST6, ST7, LI4) with the same settings as the LLLT group. Group 3 (placebo) underwent treatment with sham laser. The patients were evaluated before treatment (T1), after 5 (T2) and 10 (T3) laser applications, and 1 month later (T4). The mandibular range of motion as well as pain intensity in masticatory system was recorded at each interval. There was no significant difference in mouth opening between the groups (
p
> 0.05), but the amount of lateral excursive and protrusive movements was significantly greater in LLLT and LAT groups than the placebo group at some intervals (
p
< 0.05). The overall pain intensity and pain degree at masticatory muscles (except temporal muscle) and TMJs were significantly lower in both experimental groups than the placebo group at most intervals after therapy (
p
< 0.05). Both LLLT and LAT were effective in reducing pain and increasing excursive and protrusive mandibular motion in TMD patients. LAT could be suggested as a suitable alternative to LLLT, as it provided effective results while taking less chair time.
Purpose This study evaluated the effect of low-level laser therapy (LLLT) on decreasing pain and swelling after removal of impacted third molars. Patients and Methods This randomized, double-blinded, ...split-mouth study included patients presenting 2 symmetrically impacted mandibular third molars. In each participant, one side was randomly assigned to laser treatment and the other side received placebo. LLLT was performed by intraoral application of a 660-nm laser (200 mW, 6 J per point at 4 points) followed by extraoral application of an 810-nm laser (200 mW, 6 J per point at 3 points). Irradiation at the 810-nm wavelength was repeated on days 2 and 4 after surgery. On the control side, the treatment protocol was similar to the experimental side, but with laser simulation. The main outcomes were the degree of pain during the next 7 days and the edema coefficients on days 2, 4, and 7 after surgery. Data were analyzed using generalized linear models to determine the effect of group and time on pain level and edema coefficients. Results The final sample consisted of 40 patients. Pain level was significantly lower in the laser than in the placebo side at all time points during the experiment ( P < .05). Swelling was significantly lower in the laser than in the placebo group on days 2, 4, and 7 after surgery ( P < .05). Conclusion LLLT proved effective in decreasing the intensity of pain and swelling after removal of impacted third molars and can be recommended to alleviate patients' symptoms after surgery.
There is limited research on the clinical performance of double-thread orthodontic miniscrews. This study aimed to compare the stability of double-thread and single-thread orthodontic miniscrews and ...identify the potential associations between patient-related and location-related factors with miniscrew stability.
This retrospective cohort study involved 90 orthodontic miniscrews (45 single-thread, 45 double-thread) with identical dimensions (8 mm length, 1.6 mm diameter). The screws were inserted in various locations within the upper jaw of 83 patients (54 females, 29 males; mean age = 15.1 ± 2.4 years). Failure was defined as excessive mobility or loss of miniscrew after placement. The data recorded were patient age, gender, insertion site, side of insertion (buccal or lingual), duration of force application, and failure occurrence.
The overall success rate within the sample was 92.2%. Double-thread miniscrews exhibited a significantly higher success rate than single-thread miniscrews (P = 0.049), with 97.8% and 86.7% success rates, respectively. Gender, age, insertion location, and side of insertion did not show significant associations with failure (P > 0.05). Log-rank analysis revealed a significant difference between the two groups (P = 0.046), indicating a higher probability of survival for the double-thread design.
The overall success rate of orthodontic miniscrews was high in the present sample. Double-thread miniscrews placed in various locations within the maxillary arch demonstrated superior stability and survival rates compared to their single-thread counterparts. Therefore, double-thread miniscrews may be preferred when bone quality is inadequate, such as in young patients.
Objectives
Diagnosing cavitated proximal lesions is important for therapeutic decisions. This clinical study aimed to determine the validity of laser fluorescence (LF) and near-infrared reflection ...(NIRR) techniques for detecting early proximal cavities.
Materials and methods
The study included 43 proximal surfaces in 15 females who had limited radiolucent lesions in their bitewing radiographs. The approximal areas of interest were assessed by DIAGNOdent Pen (LF) and the Proxi interchangeable head of VistaCam iX intraoral camera (NIRR). Finally, orthodontic separators were placed in the contact points to provide enough space between the teeth. The sensitivity, specificity, and accuracy of diagnosing cavitated proximal surfaces were calculated for LF and NIRR against direct visual and tactile examination as the reference standard.
Results
On the basis of the reference standard, 34 surfaces (79.1%) were not cavitated, whereas 9 surfaces (20.9%) were cavitated and in need of restoration. The sensitivity, specificity, and accuracy of LF were 44.4%, 61.8%, and 58%, and those of NIRR were 88.9%, 14.7%, and 30%, respectively.
Conclusions
The VistaCam iX Proxi was more sensitive and DIAGNOdent Pen was more specific in detection of proximal cavities. However, none of the techniques was accurate enough to be recommended as a sole approach for proximal caries detection.
Clinical relevance
LF showed an overall superior diagnostic performance to NIRR for diagnosing proximal cavitation in permanent posterior teeth. Within the limitations of this study, neither VistaCam iX Proxi nor DIAGNOdent Pen could be considered a suitable device for diagnosing proximal cavities.
This clinical trial aimed to compare the effects of low-level laser therapy (LLLT), Er,Cr;YSGG laser, and fluoride varnish, as compared to the placebo laser on decreasing dentin hypersensitivity ...(DH). This randomized, double-blinded clinical trial included 60 jaw quadrants in 24 patients who underwent periodontal surgery. The quadrants were randomly assigned to 4 groups and received treatments as follows. Group 1: LLLT with a combination of red and infrared wavelengths, group 2: Er,Cr:YSGG laser (0.25 W and 0.5 W), group 3: fluoride varnish, and group 4: placebo laser. The sensitivity response to the cold spray was recorded using visual analogue scale (VAS) at baseline, immediately, and 1 week post-treatment. The data were analyzed by repeated measures analysis at the significance level of
P
<0.05. There was a significant reduction in DH after treatment by low-level lasers, Er,Cr:YSGG laser, or fluoride varnish compared to the baseline data (
P
<0.05), but the placebo group displayed no significant alteration in DH (
P
=0.069). At 1 week, the VAS score in the Er,Cr:YSGG laser group was significantly lower than that of the LLLT (
P
= 0.043) and placebo (
P
<0.001) groups. Furthermore, the subjects who received fluoride varnish exhibited significantly lower DH compared with the placebo group (P = 0.023). Er,Cr:YSGG laser was the most effective strategy in dealing with DH, as it caused the greatest pain reduction over the study period and showed a significant superiority over LLLT and placebo groups. Alternatively, the application of fluoride varnish could be recommended for attenuating DH following periodontal surgery.
Low-level laser therapy (LLLT) has been commonly used for the treatment of painful musculoskeletal conditions, but the results of previous studies on this subject are controversial. The aim of this ...study was to evaluate the efficacy of LLLT in the management of patients with myogenic temporomandibular joint disorders (TMDs). In this randomized, double-blind clinical trial, 20 patients with myogenic TMD were randomly divided into laser and placebo groups. In the laser group, a pulsed 810-nm low-level laser (average power 50 mW, peak power 80 W, 1,500 Hz, 120 s, 6 J, and 3.4 J/cm
2
per point) was used on painful muscles three times a week for 4 weeks. In the placebo group, the treatment was the same as that in the laser group, but without energy output. The patients were evaluated before laser therapy (T1), after six sessions of laser application (T2), at the end of treatment (T3), and 1 month after the last application (T4), and the level of pain and the amount of mouth opening were measured. There was a significant increase in mouth opening and a significant reduction of pain symptoms in the laser group (
p
< 0.05). A similar improvement was not observed in the placebo group (
p
> 0.05). Between-group comparisons revealed no significant difference in pain intensity and mouth opening measurement at any of the evaluation time points (
p
> 0.05). LLLT can produce a significant improvement in pain level and mouth opening in patients affected with myogenic TMD.
Blood extracts containing platelet products are gaining popularity in promoting healing and pulp regeneration. This study was designed to evaluate the effect of platelet-rich plasma (PRP) and ...gallium–aluminum–arsenide (GaAlAs) laser on proliferation and differentiation of human dental pulp stem cells (hDPSCs). In this ex vivo study, hDPSCs isolated from impacted mandibular third molars were cultured in
Dulbecco’s Modified Eagle’s medium
)DMEM(with 10% fetal bovine serum (FBS). After reaching the desired confluence, the cells were distributed into 4 groups, namely, control, PRP, laser, and PRP+laser for MTT assay and alkaline phosphatase (ALP) test. In the PRP and PRP+laser groups, 10% PRP was added to each well on the plate. In the laser and PRP+laser groups, as for the proliferation test, laser irradiation was carried out for 45 s, while 135 s was designated for ALP test. After 1, 3, and 5 days, cell proliferation and ALP activity were assessed using MTT and ALP colorimetric assay, respectively. Two-way ANOVA was utilized to analyze data. In PRP and PRP+laser groups, cell proliferation and viability increased until day 3 but began to decline afterwards until the 5th day. In the laser group, the increase in proliferation and viability was observed till day 5 which was less than the control group. Laser and control groups exhibited significantly higher cell viability and proliferation than both PRP and PRP+laser groups. ALP activity was more pronounced in PRP+laser, PRP, and laser in descending order; however, all were less than that of the control group. Only in the control group did the ALP activity augment during the 5-day period. Laser irradiation could induce pulp cell proliferation and demonstrated a better performance than PRP in this regard.
This study aimed to evaluate the effect of using whitening dentifrices during at-home bleaching on the shear bond strength (SBS) of resin composite to dentin, and investigate whether the increased ...polymerization time would improve SBS.
Ninety-six bovine incisors were divided into 4 groups of 24, according to the whitening treatment applied as follows: group 1, at-home bleaching + brushing with a regular dentifrice; group 2, at-home bleaching + brushing with a whitening dentifrice containing ozone; group 3, at-home bleaching + brushing with a commercial whitening dentifrice; and group 4 (control), no whitening/brushing treatment. Each group was divided into two subgroups (n = 12) to assess the effect of curing time (20 versus 80 s) on SBS. A self-etch adhesive was bonded to dentin, and after 2-day water storage, SBS was determined.
SBS was significantly affected by the whitening treatment (P = 0.03), but increasing the curing time had no significant effect on SBS (P = 0.137). Bond strength in group 1 was comparable to the control group (P > 0.05). The specimens in group 3 displayed significantly lower SBS than either group 4 or group 1 (P > 0.05). No significant difference was observed between the SBS of group 2 compared to any other group (P > 0.05). There was no significant association between the treatment group and failure type (P > 0.05).
The bonding interface was not negatively influenced by the at-home bleaching procedure. However, using a commercial whitening dentifrice during at-home bleaching produced a significant detrimental effect on SBS. Extending the curing time would have no beneficial effect on adhesion to a whitened dental substrate.
Background: This clinical trial investigated the effectiveness of two remineralizing creams on regression of white spot lesions (WSLs) after orthodontic therapy.
Materials and Methods: The study ...included patients with WSLs on their upper anterior teeth who recently completed orthodontic treatment at the Department of Orthodontics of Mashhad Dental School and two private offices. The participants were randomly assigned into three groups by treatment: (1) a 12-week regimen of a cream containing casein phosphopeptide-amorphous calcium phosphate and fluoride (MI Paste Plus); (2) a 12-week regimen of a cream containing hydroxyapatite and fluoride (Remin Pro); and (3) usual home care (control). Thirty-nine patients participated and three withdrew. The main outcomes including area, mineral content, and color of WSLs were measured at enrolment and 4, 8, and 12 weeks later, respectively. Blinding was applied for outcome assessment only. The data were analyzed by analysis of variance and repeated measures analysis at the statistical significance of P < 0.05.
Results: Over a 3-month period, the application of both MI Paste Plus and Remin Pro caused significantly greater reduction in area and significantly higher increase in mineral content of WSLs compared to the control group (P < 0.05). The appearance of WSLs improved significantly in both experimental groups (P < 0.05), but not in the control group. No side effect was observed throughout the experiment.
Conclusion: The application of either MI Paste Plus or Remin Pro was effective in reducing the area, increasing the mineral content and improving the appearance of demineralized enamel, indicating that these products could be recommended for managing postorthodontic WSLs.
This study aimed to investigate the efficacy of low-level laser irradiation when applied just before placement of resin composite on reducing postoperative sensitivity of class V lesions. In this ...randomized clinical trial, 31 patients with 62 class V cavities were included (two teeth in each participant). The teeth were randomly assigned into laser and placebo groups. After cavity preparation, the teeth in the experimental group were subjected to irradiation from a low-power red laser (630 nm, 28 mW, continuous wave, 60 s, 1.68 J), which was applied for 1 min on the axial wall of the cavity. In the control group, the same procedure was performed but with laser simulation. Then, a self-etch adhesive was applied and the cavities were restored with a microhybrid resin composite. Before treatment and on days 1, 14, and 30 after treatment, tooth sensitivity to a cold stimulus was recorded using a visual analogue scale. Data were analyzed by Friedman and Wilcoxon signed-rank tests (
p
< 0.05). Pain scores after restorative procedures were significantly lower in the laser group compared to the placebo application (
p
< 0.05). Although both groups experienced a significant improvement in pain and discomfort throughout the follow-up periods (
p
< 0.001), the changes in visual analogue scale (VAS) scores between baseline and each follow-up examination were significantly greater in the laser than the placebo group (
p
< 0.05). Low-level laser therapy (LLLT) before placement of resin composite could be suggested as a suitable approach to reduce postoperative sensitivity in class V restorations.
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