Commons have existed in the Aosta Valley’s territory for centuries, of which the most distinguishing and still lively are called consorterie. This article aims to study this peculiar form of commons, ...as well as the evolution of their legal status, focusing on national and regional legislation. This paper also seeks to analyse a regional draft bill on commons written by a technical group appointed by the regional government. Its principal goal is to provide consorterie with a new legal status in line with the results achieved by scholars, jurisprudence and national legislation. Moreover, the legislative proposal explores the regional legislative competence related thereto by proposing some innovative solutions.
Commons have existed in the Aosta Valley’s territory for centuries, of which the most distinguishing and still lively are called “Consorterie”. This article aims to study this peculiar form of ...commons, as well as the evolution of their legal status, focusing on national and regional legislation. This paper also seeks to analyse a regional draft bill on commons written by a technical group appointed by the regional government. Its principal goal is to provide Consorterie with a new legal status in line with the results achieved by scholars, jurisprudence and national legislation. Moreover, the legislative proposal explores the regional legislative competence related thereto by proposing some innovative solutions.
Oral and maxillofacial development is influenced by the lingual frenulum and also affects breathing, occlusion, sucking, swallowing, speech, among others. Ankyloglossia in the newborn may result in ...breastfeeding difficulties: maternal nipple pain and/or erosion or mastitis, poor weight gain and excessively long breastfeeds. The main objective of this work is to study the prevalence of ankyloglossia in newborns with breastfeeding difficulties.
This is a transversal descriptive study of 302 patients, between 0 and 6 months, who attended the hospital as a result of breastfeeding difficulties. All patients with sucking problems and ankyloglossia were included in this study and followed the multidisciplinary treatment protocol made up of the services of Breastfeeding, Speech Therapy and Orofacial Rehabilitation and Oral and Maxillofacial Surgery.
1,102 newborns were seen at the paediatric service of Hospital de Nens, Barcelona (Spain) during 2 years; 302 had breastfeeding difficulties and of these, 171 were diagnosed with ankyloglossia (60 girls and 111 boys). Coryllos Grade 3 ankyloglossia was the most prevalent (59.6%) type; 85 infants (49.7%) were exclusively breastfed and 26 (50.35%) were mixed fed (formula and breastfeeding). Only 43 patients had a family history of tongue-tie (25.1%).
Ankyloglossia linked to breastfeeding difficulties must be treated by a multidisciplinary team. We have found a high prevalence of the condition since the population studied are newborns with sucking problems. If a frenotomy is necessary, we recommend stimulating suction with myofunctional therapy before and after surgery to avoid scar retraction.
Angiogenesis and inflammation are closely integrated processes. Fibroblast growth factor-2 (FGF2) is a prototypic angiogenesis inducer belonging to the family of the heparin-binding FGF growth ...factors. FGF2 exerts its pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans, and integrins. A tight cross-talk exists between FGF2 and the inflammatory response in the modulation of blood vessel growth. Pentraxins act as soluble pattern recognition receptors with a wide range of functions in various pathophysiological conditions. The long-pentraxin PTX3 shares the C-terminal pentraxin-domain with short-pentraxins and possesses a unique N-terminal domain. These structural features indicate that PTX3 may have distinct biological/ligand recognition properties when compared to short-pentraxins. Co-expression of PTX3 and FGF2 has been observed in different inflammation/angiogenesis-dependent diseases. PTX3 binds FGF2 with high affinity and specificity. The interaction prevents the binding of FGF2 to its cognate tyrosine kinase receptors, leading to inhibition of the angiogenic activity of the growth factor. This suggests that PTX3 may exert a modulatory function by limiting the angiogenic activity of FGF2. An integrated approach that utilized PTX3 fragments, monoclonal antibodies, and surface plasmon resonance analysis has identified the FGF2-binding domain in the unique N-terminal extension of PTX3. On this basis, PTX3-derived synthetic peptides have been designed endowed with a significant antiangiogenic activity in vitro and in vivo. They may provide the basis for the development of novel antiangiogenic FGF2 antagonists.
The most important effect of sorption of compressed gases and supercritical fluids into glassy polymers is the reduction of the glass transition temperature (T g). This plasticization effect causes ...changes in mechanical and thermophysical properties of the polymers. In this work, a thermodynamic study based on experimental and theoretical results is addressed. New data were carried out for poly(2,6-dimethylphenylene oxide) (PPO), poly(acrylic acid) (PAA), and the copolymer vinylpyrrolidone−vinyl acetate P(VP−VA) using an inverse gas chromatographic technique. To model the T g behavior of diluent−polymer systems, a model that couples the lattice-fluid equation of state and the Gibbs−DiMarzio criterion was used. A parametric study of the influence of the physical properties (lattice coordination number, molecular weight, and binary interaction parameter) on the T g behavior is presented. The thermodynamic model fairly describes the experimental data measured in this work and gives a phenomenological representation of the retrograde vitrification for the systems PPO−CO2, PVP−CO2, and P(VP−VA)−CO2.
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► Manufacture of water-filled micro-composites. ► Encapsulation by high pressure spray process. ► Characterization of the particles, particle characteristics and water distribution. ► ...Low field H NMR and DSC suggest the presence of three different water states in the micro-composites.
The goal of the present work was to manufacture water-filled micro-composites using a high pressure encapsulation process, PGSS (Particles from Gas Saturated Solutions), and to characterize the products by different analytical methods. As shell material a vegetable fat (hydrogenated Castor oil) is used.
The obtained composites have tailor made properties like bulk density, particle size, morphology and water content. A special interest was laid on the distribution of water (core material) within the composites. Water distribution is studied using two different methods: H NMR and DSC. The analytical results suggest the presence of three different “types” of water: water between the particles, entrapped and bound water
The aim of the study was to investigate the possibility of incorporating non-ionic surfactants into pellets produced from microcrystalline cellulose by the process of extrusion/spheronization and the ...properties of the pellets. A hydrophilic surfactant, polysorbate 60 (PS 60), and two hydrophobic surfactants, sorbitan monostearate (S 60) and sorbitan monooleate (S 80), were included in the water used to form the pellets in concentrations ranging from 5 to 95%. The presence of the surfactants influenced the type of the extrusion profile and improved the ability to provide round pellets, and the addition of the surfactants changed the range of liquid levels required to prepare the pellets. At a low level, i.e., 5%, all the surfactants increased the range of water contents possible, compared to the use of water alone. At high surfactant levels, the level of liquid, which could be used, became restricted. The median size of the pellets was dependent on the type of surfactant and the concentration included in the formulation. The range of sizes produced was generally quite narrow and there were many systems with more than 90% of the pellets in the modal fraction. The highest concentration of the surfactant in water that can be used to form pellets ranged from 50% for S 60, to 80% for S 80 and 95% for PS 60. The maximum amount of the surfactant, which could be incorporated into the final pellet, however, was found to be approximately 22.5% for both the hydrophobic surfactants and 32.5% for the hydrophilic surfactant.
Infinite-dilution activity coefficients for nine classes of volatile organic compounds (paraffins, olefins, cycloparaffins, aromatics, ketones, nitriles, alcohols, esters, and chlorocompounds) in a ...series of four cyclic olefin copolymers were determined using an inverse gas chromatography technique with a packed column. Abraham’s equation of solvation was used for the evaluation of the different types of interactions between the solvents and polymers. The results are compared with the activity coefficients at infinite dilution obtained for other polymers of similar use.
Flavonoids have attracted a lot of attention due to their antioxidant, antitumor and antibacterial activities. Quercetin (3,5,7,3,4-pentahydroxyflavone) is a polyphenolic flavonoid that shows several ...biological effects including a strong inhibitory effect on the growth of several human and animal cancer cell lines and enhances the antiproliferative effect of cisplatin both in-vitro and in-vivo. In spite of a variety of its biological effects, Quercetin is very poorly soluble in water, which has limited its absorption upon oral administration. As known, the solubility of drug is often due to the increase of the surface/volume ratio which implies the increase of the number of surface atoms (or molecules) with respect to the number of bulk atoms (or molecules). With this aim, we investigated the use of supercritical antisolvent (SAS) technique for Quercetin microparticles generation finding the best operative conditions through the Peng Robinson's Equation of State. The obtained simulation behaviors were confirmed by experimental precipitation: the physicochemical characterizations of the samples were also performed. Key words: Quercetin, supercritical antisolvent technique, micronisation, physicochemical characterization
O-197 Health School For Parents Llagostera Benedico, J; Díaz Conradi, A; Jou Benito, A ...
Archives of disease in childhood,
10/2014, Letnik:
99, Številka:
Suppl 2
Journal Article
Recenzirano
Odprti dostop
BackgroundIn addition to looking after the physical and mental health of our patients, paediatricians have an educational role towards the population we attend.ObjectiveHealth education towards ...adults who are usually in charge of children: parents, grandparents and childminders.Material and methods- Antenatal and postnatal talks ABOUT childcare topics.- Paediatric Hospital Talks: sleep, feeding, teething, Internet and health.- Paediatric Cardiopulmonary Resuscitation (CPR) Workshop.- Breastfeeding Group:- Talks in Schools: Accident Prevention and First Aid, Infant Feeding.- Paediatric files: available at Hospital de Nens de Barcelona’s web: an easy reference about childcare, feeding, common infections.ResultsAttendance during these 6 years has increased: 42 people attended our activities during the first year (2008–09), compared to 900 during the last academic year (2012–13). Participants actively proposed new subjects. We detected a positive appreciation in surveys after workshops and lectures. 99.3% of respondents (year 2012/13) rated as high or very high their degree of satisfaction after the activities. 86.9% of the participants answered the survey. All those who attended the CPR workshop believed that it should be extended to all citizens in contact with children because it had helped them acquire important new skills.ConclusionsActive and increasing participation rate.We believe that the paediatric team has the duty, in these days where access to information is easy but not always truthful, of counselling families about common health problems and helping to improve the quality of life of their patients.
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