Available data indicate a worse prognosis in cancer patients with COVID-19. Surgical treatment of lung cancer in the conditions of the COVID-19 pandemic poses new challenges to ensure the ...perioperative safety of patients.
To prevent infection of patients in the perioperative period and, in case of infection, to prevent the severe course of COVID-19.
In the conditions of the COVID-19 pandemic within two months (March-April 2020) 138 patients underwent surgical treatment for malignant tumors, including 22 videothoracoscopic operations: 3 (13.6%) segmentectomies, 16 (72.7%) lobectomies, and 5 (22.7%) bilobectomies for non-small cell lung cancer.
Following the principles that ensure the prevention of infection and the prevention of severe COVID-19, we managed to avoid the first stage of the pandemic (March-April 2020) cases of infection with a new coronavirus infection in patients who underwent surgical treatment for lung cancer.
Metastatic chest lesion is rare in patients with soft palate tumors. We present a 52-year-old patient with metastatic lesion of the left ribs III-V and lung in 13 years after resection of cylindroma ...of the soft palate. The patient underwent successful chest reconstruction and atypical resection of the left lung. Isolation of the pleural cavity by xenopericardial patches and preoperative 3D CT modeled titanium implants meet all the requirements for maintaining the chest function. This approach also positively affects postoperative period and recovery. The above-described method of replacing chest defects is highly effective.
Background:
The worse prognosis in cancer patients with COVID-19 infection in the context of the pandemic, compared to that in the general population, poses new challenges to ensure the perioperative ...safety.
Aim:
To reduce the risk of infection for cancer patients in the perioperative period and to prevent severe COVID-19.
Materials and methods
: During two months of the COVID-19 (from March to April 2020), we performed 158 surgical interventions: 49 for breast cancer, 31 for lung cancer (videothoracoscopic segmental and lobar resections), 12 for stomach cancer (8 distal and 1 proximal laparoscopic subtotal gastric resections, 3 gastrectomies), 16 laparoscopic resections for colorectal cancer, 29 resections with a reconstructive plastic for malignant skin tumors, 21 palliative and diagnostic operations (diagnostic thoracoscopy and laparoscopy, laparoscopic colostomy).
Results:
Preventive administration during preparation for surgery (interferon-al-pha2b and low molecular weight heparins) and for suspected infection (antibiotics, low molecular weight heparins and dexamethasone 12 mg/day intravenously) allowed for lower rates of the new coronavirus infection (1.3%) and its severe cases (0%) during surgical treatment of malignant tumors.
Conclusion:
Surgical treatment of cancer patients in the context of a new coronavirus infection pandemic should be carried out with strict adherence to anti-epidemic measures.
ABSTRACT
Baikal-GVD has recently published its first measurement of the diffuse astrophysical neutrino flux, performed using high-energy cascade-like events. We further explore the Baikal-GVD cascade ...data set collected in 2018–2022, with the aim to identify possible associations between the Baikal-GVD neutrinos and known astrophysical sources. We leverage the relatively high angular resolution of the Baikal-GVD neutrino telescope (2–3 deg.), made possible by the use of liquid water as the detection medium, enabling the study of astrophysical point sources even with cascade events. We estimate the telescope’s sensitivity in the cascade channel for high-energy astrophysical sources and refine our analysis prescriptions using Monte-Carlo simulations. We primarily focus on cascades with energies exceeding 100 TeV, which we employ to search for correlation with radio-bright blazars. Although the currently limited neutrino sample size provides no statistically significant effects, our analysis suggests a number of possible associations with both extragalactic and Galactic sources. Specifically, we present an analysis of an observed triplet of neutrino candidate events in the Galactic plane, focusing on its potential connection with certain Galactic sources, and discuss the coincidence of cascades with several bright and flaring blazars.
ABSTRACT
The existence of high-energy astrophysical neutrinos has been unambiguously demonstrated, but their sources remain elusive. IceCube reported an association of a 290-TeV neutrino with a ...gamma-ray flare of TXS 0506 + 056, an active galactic nucleus with a compact radio jet pointing to us. Later, radio-bright blazars were shown to be associated with IceCube neutrino events with high statistical significance. These associations remained unconfirmed with the data of independent experiments. Here, we report on the detection of a rare neutrino event with the estimated energy of 224 ± 75 TeV from the direction of TXS 0506 + 056 by the new Baikal Gigaton Volume Detector (Baikal-GVD) in April 2021. This event is the highest energy cascade detected so far by the Baikal-GVD neutrino telescope from a direction below horizon. The result supports previous suggestions that radio blazars in general, and TXS 0506 + 056 in particular, are the sources of high-energy neutrinos, and opens up the cascade channel for the neutrino astronomy.
The Baikal Gigaton Volume Detector (Baikal-GVD) is a km
3
-scale neutrino detector currently under construction in Lake Baikal, Russia. The detector consists of several thousand optical sensors ...arranged on vertical strings, with 36 sensors per string. The strings are grouped into clusters of 8 strings each. Each cluster can operate as a stand-alone neutrino detector. The detector layout is optimized for the measurement of astrophysical neutrinos with energies of
∼
100 TeV and above. Events resulting from charged current interactions of muon (anti-)neutrinos will have a track-like topology in Baikal-GVD. A fast
χ
2
-based reconstruction algorithm has been developed to reconstruct such track-like events. The algorithm has been applied to data collected in 2019 from the first five operational clusters of Baikal-GVD, resulting in observations of both downgoing atmospheric muons and upgoing atmospheric neutrinos. This serves as an important milestone towards experimental validation of the Baikal-GVD design. The analysis is limited to single-cluster data, favoring nearly-vertical tracks.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Currently, the Baikal-GVD Deep Underwater Neutrino Telescope is being successfully deployed in Lake Baikal. It comprises 96 strings with 3456 optical modules. We present the status and plans for ...further deployment of the Baikal-GVD telescope and discuss the issues related to the development of the next-generation neutrino telescope in Lake Baikal.
The neutrino telescope Baikal-GVD is designed for search for high energy neutrinos whose sources are not yet reliably identified. It currently includes total of 3456 optical modules arranged on 96 ...strings, providing an effective volume of 0.6 km
for cascades with energy above 1 PeV. We discuss the first results from the partially built experiment, which is currently the largest neutrino telescope in the Northern Hemisphere and still growing up.
Deep-Water Neutrino Telescope in Lake Baikal Allakhverdyan, V. A.; Avrorin, A. D.; Avrorin, A. V. ...
Physics of atomic nuclei,
12/2021, Letnik:
84, Številka:
9
Journal Article
Recenzirano
The Baikal-GVD deep-water neutrino telescope of the cubic kilometer scale, focused on research in the field of astrophysics and particle physics, is being built in Lake Baikal. As of 2021, the ...effective volume of the detector reaches 0.4 km
3
for cascades generated by high-energy astrophysical neutrinos. The paper describes the design and basic characteristics of the telescope data acquisition system, discusses some aspects of deep-water engineering related to the deployment of the detector, and presents selected results obtained with the partially complete detector.
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