Systemic sclerosis (SSc) is a rare chronic autoimmune disease characterized by vascular abnormalities and connective tissue disorders. In 2021, the multidisciplinary team of the university hospital ...recognized a demand for oral health information among SSc patients. This study aims to describe the development of an SSc oral health booklet and its validation by people with SSc.
For the development of the booklet, the project creators employed the action research methodology involving ten stages. SSc patients evaluated the material by filling out a digital form.
One hundred and thirty-one people with SSc evaluated the booklet. It received an average score of 9.73 (SD: 0.80) in relevance, 9.82 (SD: 0.47) in explicitness, and 9.49 (SD: 0.93) in aesthetics. The final version was emailed to the participants and posted on social media.
This is the first booklet that deeply addresses these issues in Portuguese and constitutes a soft technology to instruct and assist patients with SSc.
The production of high-quality educational materials on oral health for patients with SSc is necessary. The online distribution increased its reach and had great importance in the context of the COVID-19 pandemic.
•Systemic sclerosis orofacial abnormalities impose challenges to health professionals.•Health education enables patients to self-manage systemic sclerosis.•Educational booklets must use simple language and illustrations to improve patients' understanding.•Patients' suggestions are essential to improve educational booklets.•The online distribution of educational materials improves their reach.
Since a male-related higher cardiovascular morbidity and mortality in patients with Chagas' heart disease has been reported, we aimed to investigate gender differences in myocardial damage assessed ...by cardiovascular magnetic resonance (CMR).
Retrospectively, 62 seropositive Chagas' heart disease patients referred to CMR (1.5 T) and with low probability of having significant coronary artery disease were included in this analysis. Amongst both sexes, there was a strong negative correlation between LV ejection fraction and myocardial fibrosis (male r = 0.64, female r = 0.73, both P < 0.001), with males showing significantly greater myocardial fibrosis (P = 0.002) and lower LV ejection fraction (P < 0.001) than females. After adjustment for potential confounders, gender remained associated with myocardial dysfunction, and 53% of the effect was mediated by myocardial fibrosis (P for mediation = 0.004). Also, the transmural pattern was more prevalent among male patients (23.7 vs. 9.9%, P < 0.001) as well as the myocardial heterogeneity or gray zone (2.2 vs. 1.3 g, P = 0.003).
We observed gender-related differences in myocardial damage assessed by CMR in patients with Chagas' heart disease. As myocardial fibrosis and myocardial dysfunction are associated to cardiovascular outcomes, our findings might help to understand the poorer prognosis observed in males in Chagas' disease.
Angular distributions for elastic and inelastic scattering of the
13
C+
208
Pb system have been measured at energies close to the Coulomb barrier, E
lab
= 59.8, 63.8 and 65.8 MeV. Optical Model (OM) ...and coupled channel (CC) analysis were performed using Woods-Saxon and double folding São Paulo potentials. Angular distributions for the J
π
=
3
/
2
-
excited state of
13
C
∗
(3.684 MeV) and J
π
=
3
-
of
208
Pb
∗
(2.615 MeV) were also obtained and analyzed with coupled channels calculations. A good description of the elastic angular distributions was achieved with the inclusion of the 1
n
-stripping contribution in the coupled reaction channel (CRC) calculations.
BUILDING THE NEXT GENERATION OF CLIMATE MODELERS Frassoni, Ariane; Castilho, Dayana; Rixen, Michel ...
Bulletin of the American Meteorological Society,
11/2018, Letnik:
99, Številka:
11
Journal Article
Recenzirano
Odprti dostop
Celotno besedilo
Dostopno za:
BFBNIB, DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Artisan des mots, magicien du verbe, l'écrivain brésilien João Guimarães Rosa (1908-1967) a construit une œuvre monumentale par la singularité de son univers imaginaire. Les contributions réunies ...dans cet ouvrage, à l'occasion du centenaire de sa naissance, revisitent cette œuvre ancrée dans l'imaginaire du sertão de Minas Gerais – « un lieu de la taille du monde ». Il constitue un guide indispensable pour le lecteur qui veut s'aventurer à traverser ce territoire imprévisible et fascinant. Les approches critiques plurielles y explorent les thématiques liées aux rapports entre mémoire, territoire et identité, ainsi que le dialogue que son œuvre instaure avec les traditions littéraire et philosophique ou avec d'autres formes d'expression artistique. Ces études mettent en relief le caractère dense, poétique et pluriel de l'écriture de João Guimarães Rosa qui nourrit ses contes, nouvelles et son roman Diadorim, que Mario Vargas Llosa considère comme « l'une des œuvres formellement les plus abouties du siècle ».
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