Since starting in 2010, the Large Hadron Collider (LHC) has produced collisions at an ever increasing rate. The ATLAS experiment successfully recorded the collision data with high efficiency and ...excellent data quality. Events were selected using a three-level trigger system, where each level made a more refined selection. The Level 1 (L1) trigger consisted of a custom-designed hardware trigger which seeded two higher software based trigger levels. Over 300 triggers composed a trigger menu which selected physics signatures such as electrons, muons, particle jets, etc. Each trigger consumed computing resources of the ATLAS Trigger system and offline storage. The LHC instantaneous luminosity conditions, desired physics goals of the collaboration, and the limits of the trigger infrastructure determined the composition of the ATLAS Trigger menu. We describe a trigger monitoring framework called the Cost Monitoring Framework for computing the costs of individual trigger algorithms such as data request rates and CPU consumption. This framework was used to prepare the ATLAS Trigger for data taking during increases of more than six orders of magnitude in the LHC luminosity and has been influential in guiding ATLAS Trigger computing upgrades.
Discovered in 2012, the Higgs boson has opened a new window on nature. The latest searches for its rare and non-Standard Model decays with the ATLAS detector at the LHC are presented. They represent ...a promising probe of the 1st and 2nd generation Yukawa couplings, and of new physics. Searches for rare exclusive decays of the Higgs boson to a meson and a photon are presented. Also presented are four searches for decays of the Higgs boson to pairs of beyond the Standard Model resonances, in various final states.
Interindividual and intraindividual variations in aryl hydrocarbon hydroxylase (AHH) induction by 3-methylcholanthrene were studied in cultured lymphocytes from normal adult volunteers. Using eight ...pairs of monozygotic and eight pairs of dizygotic twins, we examined to what extent these variations are controlled by heritable factors and whether AHH inducibility correlations in an individual with the plasma half-lives of three drugs. Substantial overestimation of the induction ratio (fold inducibility) may occur if the nonlinearity of the assay standard curve is not considered. Fold inducibility remains relatively constant for an individual, but large intraindividual variations occur in absolute "control" and "induced" AHH activities. Fetal calf serum may contain inducers of AHH activity that vary with the particular lot of serum, thereby rendering the apparent induction ratio an imprecise indicator of genetic susceptibility to induction by 3-methylcholanthrene. The index of heritability for AHH fold inducibility in twins studied with different lots of fetal calf serum (0.80) or with a single lot of fetal calf serum (0.77) suggests nonetheless that genetic rather than environmental factors are mainly responsible for interindividual variations in AHH inducibility by 3-methylcholanthrene in human lymphocytes. In these twins a significant but poor correlation (r=-0.551; 0.03 less than p less than 0.05) occurs between AHH inducibility in culture and the plasma antipyring half-life, but not between AHH inducibility and phenylbutazone or bishdroxycoumarin half-lives.
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