Collective events can generate intense emotions, shape group identities, and forge strong bonds. Do these effects extend to remote participation, and what are the psychological mechanisms ...underpinning their social power? We monitored psycho-physiological activity among groups of basketball fans who either attended games in-person (in a stadium) or watched games live on television in small groups. In-person attendance was associated with greater synchronicity in autonomic nervous system activation at the group level, which resulted in more transformative experiences and contributed to stronger identity fusion. Our findings suggest that the social effects of sports depend substantially on the inter-personal dynamics unfolding among fans, rather than being prompted simply by watching the game itself. Given the increasing prevalence of virtual experiences, this has potentially wide-reaching implications for many domains of collective human interaction.
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•Bilayer hybrid structures of titanium alloy Ti64 and its composites were fabricated using blended elemental powder metallurgy.•Bilayer structures were mechanically tested for their ...response to compression under quasi-static and dynamic loading.•Experimental data from high strain rate compression using split Hopkinson pressure bar and high speed video recording are in compliance with used finite element analysis modeling.•A generalized scheme of deformation and destruction of the studied bilayer structures was proposed that account on the rate of external compressive load applied.
Bilayer structures of titanium alloy Ti-6Al-4V (Ti64) and metal matrix composites (MMC) on the base of this alloy reinforced with 5, and 10 % (vol.) of TiC or TiB particles were made using press-and-sinter Blended Elemental Powder Metallurgy (BEPM). The mechanical behavior of these structures was studied under quasi-static and high strain rate compression. Dynamic tests with compression velocity in the range 4–15 m/s (820–2880 s−1) were done using the split Hopkinson pressure bar (SHPB), whereas the quasi-static tests were performed with compression velocity of 0.0005 m/s (10−3 s−1). Stress–strain curves were obtained and the effect of phase composition, microstructure, and strain rate was analyzed and discussed. Current results were compared with previous studies conducted on homogeneous MMCs and Ti64 alloy tested in similar conditions. The deformation mechanism evaluated from the microstructure analysis of the samples was verified using in-situ high-speed camera recordings. Numerical simulation based on Finite Element Analysis was conducted to further investigate the behavior of the samples during the SHPB trials. Generalized scheme of the deformation and damage process of two-layer alloy/composites hybrids as a function of compression rate was proposed.
The observation of gravitational waves is hindered by the presence of transient noise (glitches). We study data from the third observing run of the Advanced LIGO detectors, and identify new glitch ...classes. Using training sets assembled by monitoring of the state of the detector, and by citizen-science volunteers, we update the Gravity Spy machine-learning algorithm for glitch classification. We find that a new glitch class linked to ground motion at the detector sites is especially prevalent, and identify two subclasses of this linked to different types of ground motion. Reclassification of data based on the updated model finds that 27 % of all transient noise at LIGO Livingston belongs to the new glitch class, making it the most frequent source of transient noise at that site. Our results demonstrate both how glitch classification can reveal potential improvements to gravitational-wave detectors, and how, given an appropriate framework, citizen-science volunteers may make discoveries in large data sets.
EAU Guidelines on Chronic Pelvic Pain Fall, M.; Baranowski, A.P.; Fowler, C.J. ...
European urology,
12/2004, Letnik:
46, Številka:
6
Journal Article
Recenzirano
On behalf of the European Association of Urology (EAU) guidelines for diagnosis, therapy and follow-up of chronic pelvic pain patients were established.
Guidelines were compiled by a working group ...and based on current literature following a systematic review using MEDLINE. References were weighted by the panel of experts.
The full text of the guidelines is available through the EAU Central Office and the EAU website (
www.uroweb.org). This article is a short version of this text and summarises the main conclusions from the guidelines on management of chronic pelvic pain.
A guidelines text is presented including chapters on prostate pain and bladder pain syndromes, urethral pain, scrotal pain, pelvic pain in gynaecological practice, role of the pelvic floor and pudendal nerve, general treatment of chronic pelvic pain and neuromodulation. These guidelines have been drawn up to provide support in the management of the large and difficult group of patients suffering from chronic pelvic pain.
Aims/hypothesis Fatty acids of marine origin, i.e. docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) act as hypolipidaemics, but they do not improve glycaemic control in obese and diabetic ...patients. Thiazolidinediones like rosiglitazone are specific activators of peroxisome proliferator-activated receptor γ, which improve whole-body insulin sensitivity. We hypothesised that a combined treatment with a DHA and EPA concentrate (DHA/EPA) and rosiglitazone would correct, by complementary additive mechanisms, impairments of lipid and glucose homeostasis in obesity. Methods Male C57BL/6 mice were fed a corn oil-based high-fat diet. The effects of DHA/EPA (replacing 15% dietary lipids), rosiglitazone (10 mg/kg diet) or a combination of both on body weight, adiposity, metabolic markers and adiponectin in plasma, as well as on liver and muscle gene expression and metabolism were analysed. Euglycaemic-hyperinsulinaemic clamps were used to characterise the changes in insulin sensitivity. The effects of the treatments were also analysed in dietary obese mice with impaired glucose tolerance (IGT). Results DHA/EPA and rosiglitazone exerted additive effects in prevention of obesity, adipocyte hypertrophy, low-grade adipose tissue inflammation, dyslipidaemia and insulin resistance, while inducing adiponectin, suppressing hepatic lipogenesis and decreasing muscle ceramide concentration. The improvement in glucose tolerance reflected a synergistic stimulatory effect of the combined treatment on muscle glycogen synthesis and its sensitivity to insulin. The combination treatment also reversed dietary obesity, dyslipidaemia and IGT. Conclusions/interpretation DHA/EPA and rosiglitazone can be used as complementary therapies to counteract dyslipidaemia and insulin resistance. The combination treatment may reduce dose requirements and hence the incidence of adverse side effects of thiazolidinedione therapy.
Abstract The strong stratification of the Bay of Bengal (BoB) causes rapid variations in sea surface temperature (SST) that influence the development of monsoon rainfall systems. This stratification ...is driven by the salinity difference between the fresh surface waters of the northern bay and the supply of warm, salty water by the Southwest Monsoon Current (SMC). Despite the influence of the SMC on monsoon dynamics, observations of this current during the monsoon are sparse. Using data from high-resolution in situ measurements along an east–west section at 8°N in the southern BoB, we calculate that the northward transport during July 2016 was between 16.7 and 24.5 Sv (1 Sv ≡ 10 6 m 3 s −1 ), although up to ⅔ of this transport is associated with persistent recirculating eddies, including the Sri Lanka Dome. Comparison with climatology suggests the SMC in early July was close to the average annual maximum strength. The NEMO 1/12° ocean model with data assimilation is found to faithfully represent the variability of the SMC and associated water masses. We show how the variability in SMC strength and position is driven by the complex interplay between local forcing (wind stress curl over the Sri Lanka Dome) and remote forcing (Kelvin and Rossby wave propagation). Thus, various modes of climatic variability will influence SMC strength and location on time scales from weeks to years. Idealized one-dimensional ocean model experiments show that subsurface water masses advected by the SMC significantly alter the evolution of SST and salinity, potentially impacting Indian monsoon rainfall.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Abstract
STUDY QUESTION
What are the European trends and developments in ART and IUI in 2015 as compared to previous years?
SUMMARY ANSWER
The 19th ESHRE report on ART shows a continuing expansion of ...treatment numbers in Europe, and this increase, the variability in treatment modalities and the rising contribution to the birth rates in most participating countries all point towards the increasing impact of ART on European society.
WHAT IS KNOWN ALREADY
Since 1997, the ART data generated by national registries have been collected, analysed and reported in 18 manuscripts published in Human Reproduction.
STUDY DESIGN, SIZE, DURATION
Collection of European data by the European IVF-Monitoring Consortium (EIM) for ESHRE. The data for treatments performed between 1 January and 31 December 2015 in 38 European countries were provided by national registries or on a voluntary basis by clinics or professional societies.
PARTICIPANTS/MATERIALS, SETTINGS, METHODS
From 1343 institutions in 38 countries offering ART services a total of 849 811 treatment cycles, involving 155 960 with IVF, 385676 with ICSI, 218098 with frozen embryo replacement (FER), 21 041 with preimplantation genetic testing (PGT), 64 477 with egg donation (ED), 265 with IVM and 4294 with FOR were recorded. European data on IUI using husband/partner’s semen (IUI-H) and donor semen (IUI-D) were reported from 1352 institutions offering IUI in 25 countries and 21 countries, respectively. A total of 139 050 treatments with IUI-H and 49 001 treatments with IUI-D were included.
MAIN RESULTS AND THE ROLE OF CHANCE
In 18 countries (14 in 2014) with a population of approximately 286 million inhabitants, in which all institutions contributed to their respective national registers, a total of 409 771 treatment cycles were performed, corresponding to 1432 cycles per million inhabitants (range: 727–3068 per million). After IVF the clinical pregnancy rates (PRs) per aspiration and per transfer were slightly lower in 2015 as compared to 2014, at 28.5 and 34.6% versus 29.9 and 35.8%, respectively. After ICSI, the corresponding PR achieved per aspiration and per transfer in 2015 were also slightly lower than those achieved in 2014 (26.2 and 33.2% versus 28.4 and 35.0%, respectively). On the other hand, after FER with own embryos the PR per thawing continued to rise from 27.6% in 2014 to 29.2% in 2015. After ED a slightly lower PR per embryo transfer was achieved: 49.6% per fresh transfer (50.3% in 2014) and 43.4% for FOR (48.7% in 2014). The delivery rates (DRs) after IUI remained stable at 7.8% after IUI-H (8.5% in 2014) and at 12.0% after IUI-D (11.6% in 2014). In IVF and ICSI together, 1, 2, 3 and ≥4 embryos were transferred in 37.7, 53.9, 7.9 and in 0.5% of all treatments, respectively (corresponding to 34.9, 54.5, 9.9 and in 0.7% in 2014). This evolution towards the transfer of fewer embryos in both IVF and ICSI resulted in a proportion of singleton, twin and triplet DR of 83.1, 16.5 and 0.4%, respectively (compared to 82.5, 17.0 and 0.5%, respectively, in 2014). Treatments with FER in 2015 resulted in twin and triplet DR of 12.3 and 0.3%, respectively (versus 12.4 and 0.3% in 2014). Twin and triplet delivery rates after IUI-H were 8.9 and 0.5%, respectively (in 2014: 9.5 and 0.3%), and 7.3 and 0.6% after IUI-D (in 2014: 7.7 and 0.3%).
LIMITATIONS, REASONS FOR CAUTION
The methods of data collection and reporting vary among European countries. The EIM receives aggregated data from various countries with variable levels of completeness. Registries from a number of countries have failed to provide adequate data about the number of initiated cycles and deliveries. As long as incomplete data are provided, the results should be interpreted with caution.
WIDER IMPLICATIONS OF THE FINDINGS
The 19th EIM report on ART shows a continuing expansion of treatment numbers in Europe. The number of treatments reported, the variability in treatment modalities and the rising contribution to the birth rates in most participating countries point towards the increasing impact of ART on reproduction in Europe. Being the largest data collection on ART worldwide, detailed information about ongoing developments in the field is provided.
STUDY FUNDING/COMPETING INTEREST(S)
The study has no external funding and all costs are covered by ESHRE. There are no competing interests.
BoBBLE Vinayachandran, P. N.; Matthews, Adrian J.; Kumar, K. Vijay ...
Bulletin of the American Meteorological Society,
08/2018, Letnik:
99, Številka:
8
Journal Article
Recenzirano
Odprti dostop
The Bay of Bengal (BoB) plays a fundamental role in controlling the weather systems that make up the South Asian summer monsoon system. In particular, the southern BoB has cooler sea surface ...temperatures (SST) that influence ocean–atmosphere interaction and impact the monsoon. Compared to the southeastern BoB, the southwestern BoB is cooler, more saline, receives much less rain, and is influenced by the summer monsoon current (SMC). To examine the impact of these features on the monsoon, the BoB Boundary Layer Experiment (BoBBLE) was jointly undertaken by India and the United Kingdom during June–July 2016. Physical and biogeochemical observations were made using a conductivity–temperature–depth (CTD) profiler, five ocean gliders, an Oceanscience Underway CTD (uCTD), a vertical microstructure profiler (VMP), two acoustic Doppler current profilers (ADCPs), Argo floats, drifting buoys, meteorological sensors, and upper-air radiosonde balloons. The observations were made along a zonal section at 8°N between 85.3° and 89°E with a 10-day time series at 8°N, 89°E. This paper presents the new observed features of the southern BoB from the BoBBLE field program, supported by satellite data. Key results from the BoBBLE field campaign show the Sri Lanka dome and the SMC in different stages of their seasonal evolution and two freshening events during which salinity decreased in the upper layer, leading to the formation of thick barrier layers. BoBBLE observations were taken during a suppressed phase of the intraseasonal oscillation; they captured in detail the warming of the ocean mixed layer and the preconditioning of the atmosphere to convection.
Celotno besedilo
Dostopno za:
BFBNIB, DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Abstract
STUDY QUESTION
What are the European trends and developments in ART and IUI in 2014 as compared to previous years?
SUMMARY ANSWER
The 18th ESHRE report on ART shows a continuing expansion of ...both treatment numbers in Europe and more variability in treatment modalities resulting in a rising contribution to the birth rates in most participating countries.
WHAT IS KNOWN ALREADY
Since 1997, ART data generated by national registries have been collected, analysed by the European IVF-monitoring (EIM) Consortium and reported in 17 manuscripts published in Human Reproduction.
STUDY DESIGN, SIZE, DURATION
Continuous collection of European data by the EIM for ESHRE. The data for treatments performed in 2014 between 1 January and 31 December in 39 European countries were provided by national registries or on a voluntary basis by clinics or professional societies.
PARTICIPANTS/MATERIALS, SETTING, METHODS
From 39 countries and 1279 institutions offering ART services, a total of 776 556 treatment cycles, involving 146 148 with IVF, 362 285 with ICSI, 192 027 with frozen embryo replacement (FER), 15 894 with PGT, 56 516 with egg donation (ED), 292 with IVM and 3404 with frozen oocyte replacement (FOR) were reported. European data on IUI using husband/partner's semen (IUI-H) and donor semen (IUI-D) were reported from 1364 institutions offering IUI in 26 countries and 21 countries, respectively. A total of 120 789 treatments with IUI-H and 49 163 treatments with IUI-D were included.
MAIN RESULTS AND THE ROLE OF CHANCE
In 14 countries (17 in 2013), where all institutions contributed to their respective national registers, a total of 291 235 treatment cycles were performed in a population of ~208 million inhabitants, corresponding to 1925 cycles per million inhabitants (range: 423-2978 per million inhabitants). After treatment with IVF the clinical pregnancy rates (PR) per aspiration and per transfer were marginally higher in 2014 than in 2013, at 29.9 and 35.8% versus 29.6 and 34.5%, respectively. After treatment with ICSI the PR per aspiration and per transfer were also higher than those achieved in 2013 (28.4 and 35.0% versus 27.8 and 32.9%, respectively). After FER with own embryos the PR continued to rise, from 27.0% in 2013 to 27.6% in 2014. After ED a similar trend was observed with PR reaching 50.3% per fresh transfer (49.8% in 2013) and 48.7% for FOR (46.4% in 2013). The delivery rates (DR) after IUI remained stable at 8.5% after IUI-H (8.6% in 2013) and at 11.6% after IUI-D (11.1% in 2013). In IVF and ICSI together, 1, 2, 3 and ≥4 embryos were transferred in 34.9, 54.5, 9.9 and in 0.7% of all treatments, respectively (corresponding to 31.4%, 56.3, 11.5% and 1% in 2013). This evolution in embryo transfer strategy in both IVF and ICSI resulted in a singleton, twin and triplet DR of 82.5, 17.0 and 0.5%, respectively (compared to 82.0, 17.5 and 0.5%, respectively, in 2013). Treatments with FER in 2014 resulted in a twin and triplet DR of 12.4 and 0.3%, respectively (versus 12.5 and 0.3% in 2013). Twin and triplet DR after IUI were 9.5 and 0.3%, respectively, after IUI-H (in 2013:9.5 and 0.6%) and 7.7 and 0.3% after IUI-D (in 2013: 7.5 and 0.3%).
LIMITATION, REASONS FOR CAUTION
The method of data collection and reporting varies among European countries. The EIM receives aggregated data from various countries with variable levels of completeness. Registries from a number of countries have failed to provide adequate data about the number of initiated cycles and deliveries. As long as incomplete data are provided, the results should be interpreted with caution.
WIDER IMPLICATIONS OF THE FINDINGS
The 18th ESHRE report on ART shows a continuing expansion of treatment numbers in Europe. The number of treatments reported, the variability in treatment modalities and the rising contribution to the birth rates in most participating countries point towards the increasing impact of ART on reproduction in Europe. Being the largest data collection on ART, the report gives detailed information about ongoing developments in the field.
STUDY FUNDING/COMPETING INTEREST(S)
The study has no external funding and all costs are covered by ESHRE. There are no competing interests.
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