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zadetkov: 21
1.
  • High-Throughput Analysis Re... High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2
    Becker, Winston R.; Ober-Reynolds, Benjamin; Jouravleva, Karina ... Molecular cell, 08/2019, Letnik: 75, Številka: 4
    Journal Article
    Recenzirano
    Odprti dostop

    Argonaute proteins loaded with microRNAs (miRNAs) or small interfering RNAs (siRNAs) form the RNA-induced silencing complex (RISC), which represses target RNA expression. Predicting the biological ...
Celotno besedilo
Dostopno za: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP

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2.
  • Organization of the human i... Organization of the human intestine at single-cell resolution
    Hickey, John W; Becker, Winston R; Nevins, Stephanie A ... Nature, 07/2023, Letnik: 619, Številka: 7970
    Journal Article
    Recenzirano
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    The intestine is a complex organ that promotes digestion, extracts nutrients, participates in immune surveillance, maintains critical symbiotic relationships with microbiota and affects overall ...
Celotno besedilo
Dostopno za: GEOZS, IJS, IMTLJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK, ZAGLJ
3.
  • Single-cell analyses define... Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer
    Becker, Winston R; Nevins, Stephanie A; Chen, Derek C ... Nature genetics, 07/2022, Letnik: 54, Številka: 7
    Journal Article
    Recenzirano
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    To chart cell composition and cell state changes that occur during the transformation of healthy colon to precancerous adenomas to colorectal cancer (CRC), we generated single-cell chromatin ...
Celotno besedilo
Dostopno za: EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
4.
  • A Quantitative and Predicti... A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins
    Jarmoskaite, Inga; Denny, Sarah K.; Vaidyanathan, Pavanapuresan P. ... Molecular cell, 06/2019, Letnik: 74, Številka: 5
    Journal Article
    Recenzirano
    Odprti dostop

    High-throughput methodologies have enabled routine generation of RNA target sets and sequence motifs for RNA-binding proteins (RBPs). Nevertheless, quantitative approaches are needed to capture the ...
Celotno besedilo
Dostopno za: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP

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5.
  • A comprehensive thermodynam... A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4
    Sadée, Christoph; Hagler, Lauren D; Becker, Winston R ... Nature communications, 08/2022, Letnik: 13, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Genomic methods have been valuable for identifying RNA-binding proteins (RBPs) and the genes, pathways, and processes they regulate. Nevertheless, standard motif descriptions cannot be used to ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK
6.
  • High-throughput biochemical... High-throughput biochemical profiling reveals functional adaptation of a bacterial Argonaute
    Ober-Reynolds, Benjamin; Becker, Winston R.; Jouravleva, Karina ... Molecular cell, 04/2022, Letnik: 82, Številka: 7
    Journal Article
    Recenzirano
    Odprti dostop

    Argonautes are nucleic acid-guided proteins that perform numerous cellular functions across all domains of life. Little is known about how distinct evolutionary pressures have shaped each Argonaute’s ...
Celotno besedilo
Dostopno za: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
7.
  • Biaxial mechanical properti... Biaxial mechanical properties of swine uterosacral and cardinal ligaments
    Becker, Winston R.; De Vita, Raffaella Biomechanics and modeling in mechanobiology, 06/2015, Letnik: 14, Številka: 3
    Journal Article
    Recenzirano

    Mechanical alterations to pelvic floor ligaments may contribute to the development and progression of pelvic floor disorders. In this study, the first biaxial elastic and viscoelastic properties were ...
Celotno besedilo
Dostopno za: EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
8.
  • Demonstration of protein co... Demonstration of protein cooperativity mediated by RNA structure using the human protein PUM2
    Becker, Winston R; Jarmoskaite, Inga; Vaidyanathan, Pavanapuresan P ... RNA, 06/2019, Letnik: 25, Številka: 6
    Journal Article
    Recenzirano
    Odprti dostop

    Posttranslational gene regulation requires a complex network of RNA-protein interactions. Cooperativity, which tunes response sensitivities, originates from protein-protein interactions in many ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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9.
  • Quantification of Cas9 bind... Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement
    Boyle, Evan A; Becker, Winston R; Bai, Hua B ... Science advances, 02/2021, Letnik: 7, Številka: 8
    Journal Article
    Recenzirano
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    The RNA-guided nuclease Cas9 has unlocked powerful methods for perturbing both the genome through targeted DNA cleavage and the regulome through targeted DNA binding, but limited biochemical data ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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10.
  • From Cell Death to Embryo A... From Cell Death to Embryo Arrest: Mathematical Models of Human Preimplantation Embryo Development
    Hardy, K.; Spanos, S.; Becker, D. ... Proceedings of the National Academy of Sciences - PNAS, 02/2001, Letnik: 98, Številka: 4
    Journal Article
    Recenzirano
    Odprti dostop

    Human preimplantation embryos exhibit high levels of apoptotic cells and high rates of developmental arrest during the first week in vitro. The relation between the two is unclear and difficult to ...
Celotno besedilo
Dostopno za: BFBNIB, NMLJ, NUK, PNG, SAZU, UL, UM, UPUK

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zadetkov: 21

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