Recent publications have argued that there are potentially serious consequences for researchers in recognising distinct genera in the terminal fusarioid clade of the family Nectriaceae. Thus, an ...alternate hypothesis, namely a very broad concept of the genus Fusarium was proposed. In doing so, however, a significant body of data that supports distinct genera in Nectriaceae based on morphology, biology, and phylogeny is disregarded. A DNA phylogeny based on 19 orthologous protein-coding genes was presented to support a very broad concept of Fusarium at the F1 node in Nectriaceae. Here, we demonstrate that re-analyses of this dataset show that all 19 genes support the F3 node that represents Fusarium sensu stricto as defined by F. sambucinum (sexual morph synonym Gibberella pulicaris). The backbone of the phylogeny is resolved by the concatenated alignment, but only six of the 19 genes fully support the F1 node, representing the broad circumscription of Fusarium. Furthermore, a re-analysis of the concatenated dataset revealed alternate topologies in different phylogenetic algorithms, highlighting the deep divergence and unresolved placement of various Nectriaceae lineages proposed as members of Fusarium. Species of Fusarium s. str. are characterised by Gibberella sexual morphs, asexual morphs with thin- or thick-walled macroconidia that have variously shaped apical and basal cells, and trichothecene mycotoxin production, which separates them from other fusarioid genera. Here we show that the Wollenweber concept of Fusarium presently accounts for 20 segregate genera with clear-cut synapomorphic traits, and that fusarioid macroconidia represent a character that has been gained or lost multiple times throughout Nectriaceae. Thus, the very broad circumscription of Fusarium is blurry and without apparent synapomorphies, and does not include all genera with fusarium-like macroconidia, which are spread throughout Nectriaceae (e.g., Cosmosporella, Macroconia, Microcera). In this study four new genera are introduced, along with 18 new species and 16 new combinations. These names convey information about relationships, morphology, and ecological preference that would otherwise be lost in a broader definition of Fusarium. To assist users to correctly identify fusarioid genera and species, we introduce a new online identification database, Fusarioid-ID, accessible at www.fusarium.org. The database comprises partial sequences from multiple genes commonly used to identify fusarioid taxa (act1, CaM, his3, rpb1, rpb2, tef1, tub2, ITS, and LSU). In this paper, we also present a nomenclator of names that have been introduced in Fusarium up to January 2021 as well as their current status, types, and diagnostic DNA barcode data. In this study, researchers from 46 countries, representing taxonomists, plant pathologists, medical mycologists, quarantine officials, regulatory agencies, and students, strongly support the application and use of a more precisely delimited Fusarium (= Gibberella) concept to accommodate taxa from the robust monophyletic node F3 on the basis of a well-defined and unique combination of morphological and biochemical features. This F3 node includes, among others, species of the F. fujikuroi, F. incarnatum-equiseti, F. oxysporum, and F. sambucinum species complexes, but not species of Bisifusarium F. dimerum species complex (SC), Cyanonectria (F. buxicola SC), Geejayessia (F. staphyleae SC), Neocosmospora (F. solani SC) or Rectifusarium (F. ventricosum SC). The present study represents the first step to generating a new online monograph of Fusarium and allied fusarioid genera (www.fusarium.org).
Novel species of fungi described in this study include those from various countries as follows: Australia, Chaetopsina eucalypti on Eucalyptus leaf litter, Colletotrichum cobbittiense from Cordyline ...stricta × C. australis hybrid,
Cyanodermella banksiae on Banksia ericifolia subsp. macrantha, Discosia macrozamiae on Macrozamia miquelii, Elsinoë banksiigena on Banksia marginata, Elsinoë elaeocarpi on Elaeocarpus sp., Elsinoë leucopogonis on Leucopogon
sp., Helminthosporium livistonae on Livistona australis, Idriellomyces eucalypti (incl. Idriellomyces gen. nov.) on Eucalyptus obliqua, Lareunionomyces eucalypti on Eucalyptus sp., Myrotheciomyces corymbiae (incl. Myrotheciomyces
gen. nov., Myrotheciomycetaceae fam. nov.), Neolauriomyces eucalypti (incl. Neolauriomyces gen. nov., Neolauriomycetaceae fam. nov.) on Eucalyptus sp., Nullicamyces eucalypti (incl. Nullicamyces gen. nov.) on Eucalyptus leaf litter,
Oidiodendron eucalypti on Eucalyptus maidenii, Paracladophialophora cyperacearum (incl. Paracladophialophoraceae fam. nov.) and Periconia cyperacearum on leaves of Cyperaceae, Porodiplodia livistonae (incl. Porodiplodia gen. nov., Porodiplodiaceae
fam. nov.) on Livistona australis, Sporidesmium melaleucae (incl. Sporidesmiales ord. nov.) on Melaleuca sp., Teratosphaeria sieberi on Eucalyptus sieberi, Thecaphora australiensis in capsules of a variant of Oxalis exilis. Brazil,
Aspergillus serratalhadensis from soil, Diaporthe pseudoinconspicua from Poincianella pyramidalis, Fomitiporella pertenuis on dead wood, Geastrum magnosporum on soil, Marquesius aquaticus (incl. Marquesius gen. nov.) from submerged decaying twig
and leaves of unidentified plant, Mastigosporella pigmentata from leaves of Qualea parviflorae, Mucor souzae from soil, Mycocalia aquaphila on decaying wood from tidal detritus, Preussia citrullina as endophyte from leaves of Citrullus lanatus,
Queiroziella brasiliensis (incl. Queiroziella gen. nov.) as epiphytic yeast on leaves of Portea leptantha, Quixadomyces cearensis (incl. Quixadomyces gen. nov.) on decaying bark, Xylophallus clavatus on rotten wood. Canada, Didymella cari
on Carum carvi and Coriandrum sativum. Chile, Araucasphaeria foliorum (incl. Araucasphaeria gen. nov.) on Araucaria araucana, Aspergillus tumidus from soil, Lomentospora valparaisensis from soil. Colombia, Corynespora pseudocassiicola
on Byrsonima sp., Eucalyptostroma eucalyptorum on Eucalyptus pellita, Neometulocladosporiella eucalypti (incl. Neometulocladosporiella gen. nov.) on Eucalyptus grandis × urophylla, Tracylla eucalypti (incl. Tracyllaceae
fam. nov., Tracyllalales ord. nov.) on Eucalyptus urophylla. Cyprus, Gyromitra anthracobia (incl. Gyromitra subg. Pseudoverpa) on burned soil. Czech Republic, Lecanicillium restrictum from the surface of the wooden barrel, Lecanicillium
testudineum from scales of Trachemys scripta elegans. Ecuador, Entoloma yanacolor and Saproamanita quitensis on soil. France, Lentithecium carbonneanum from submerged decorticated Populus branch. Hungary, Pleuromyces hungaricus
(incl. Pleuromyces gen. nov.) from a large Fagus sylvatica log. Iran, Zymoseptoria crescenta on Aegilops triuncialis. Malaysia, Ochroconis musicola on Musa sp. Mexico, Cladosporium michoacanense from soil. New Zealand,
Acrodontium metrosideri on Metrosideros excelsa, Polynema podocarpi on Podocarpus totara, Pseudoarthrographis phlogis (incl. Pseudoarthrographis gen. nov.) on Phlox subulata. Nigeria, Coprinopsis afrocinerea on soil. Pakistan, Russula
mansehraensis on soil under Pinus roxburghii. Russia, Baorangia alexandri on soil in deciduous forests with Quercus mongolica. South Africa, Didymocyrtis brachylaenae on Brachylaena discolor. Spain, Alfaria dactylis from
fruit of Phoenix dactylifera, Dothiora infuscans from a blackened wall, Exophiala nidicola from the nest of an unidentified bird, Matsushimaea monilioides from soil, Terfezia morenoi on soil. United Arab Emirates, Tirmania honrubiae on soil. USA,
Arxotrichum wyomingense (incl. Arxotrichum gen. nov.) from soil, Hongkongmyces snookiorum from submerged detritus from a fresh water fen, Leratiomyces tesquorum from soil, Talaromyces tabacinus on leaves of Nicotiana tabacum. Vietnam,
Afroboletus vietnamensis on soil in an evergreen tropical forest, Colletotrichum condaoense from Ipomoea pes-caprae. Morphological and culture characteristics along with DNA barcodes are provided.
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•Quantum biochemistry calculation of the binding energy of SERMS with OHT and RAL.•SERMs-OHT binds more strongly when compared to SERMs-RAL.•Selective estrogen receptor modulators are ...very effective against breast cancer.•MFCC scheme was used for individual contribution of each amino acid residue.
In this work we employed quantum biochemistry methods based on the density functional theory (DFT) model and the MFCC (Molecular Fractionation with Conjugate Caps) scheme to unveil the detailed binding energy features of the tissue-selective synthetic agents SERMs (selective estrogen receptor modulators) 4-hydroxytamoxifen (OHT) and raloxifene (RAL), widely used in the breast cancer treatment, co-crystallized with the estrogen receptor α (ERα). Our theoretical/computational results demonstrated that the total binding energies of OHT and RAL to the ERα ligand-pocket correlate with the experimental binding affinity. Besides, we found that SERMs-OHT binds stronger when compared to SERMs-RAL, confirming experimental data, whose main contributions to the total SERMs-ERα binding energy are due to the amino acid residues in decreasing sequence D351>E542>D538>E353>E423, an important information to understand their binding mechanisms.
This work presents a study of distributed passive harmonic filter design to minimize harmonic distortions caused by nonlinear loads in residential customers. The main objectives in this study are: 1) ...to improve the power factor, 2) to reduce current and voltage distortions to standard limits, and 3) to reduce electrical losses. In this sense, several measurements that were carried out in some domestic customers of the metropolitan distribution grid of Belem City, in the North of Brazil, have characterized as the main harmonic distribution current sources the third, fifth, and seventh harmonic components. According to the results obtained and considering the impacts caused in the distribution grid, a distributed filtering strategy is proposed using passive-tuned filters of low costs to be installed in the customers.
The Double Chooz antineutrino detectors Abe, Y.; Alba, J.; Barriere, J. C. ...
The European physical journal. C, Particles and fields,
09/2022, Letnik:
82, Številka:
9
Journal Article
Recenzirano
Odprti dostop
This article describes the setup and performance of the near and far detectors in the Double Chooz experiment. The electron antineutrinos of the Chooz nuclear power plant were measured in two ...identically designed detectors with different average baselines of about 400 m and 1050 m from the two reactor cores. Over many years of data taking the neutrino signals were extracted from interactions in the detectors with the goal of measuring a fundamental parameter in the context of neutrino oscillation, the mixing angle
θ
13
. The central part of the Double Chooz detectors was a main detector comprising four cylindrical volumes filled with organic liquids. From the inside towards the outside there were volumes containing gadolinium-loaded scintillator, gadolinium-free scintillator, a buffer oil and, optically separated, another liquid scintillator acting as veto system. Above this main detector an additional outer veto system using plastic scintillator strips was installed. The technologies developed in Double Chooz were inspiration for several other antineutrino detectors in the field. The detector design allowed implementation of efficient background rejection techniques including use of pulse shape information provided by the data acquisition system. The Double Chooz detectors featured remarkable stability, in particular for the detected photons, as well as high radiopurity of the detector components.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
This paper explores the performance of alternative voltage control strategy applied to direct drive synchronous wind generators, more specifically with permanent magnetic (PMSG). The reactive power ...control of the grid-side converter is investigated for voltage control purposes. In Brazil, the Grid National Operator (ONS) requires that wind turbines stay connected to the grid during voltage dips, but does not stipulate yet the need of reactive power injection during faults in the electric grid. It just specifies the Low Voltage Ride-Through (LVRT) capability curve for voltage dips that the wind generators should follow to avoid the trip of the under-voltage relay. Criteria of the synchronous wind generators protection are evaluated starting from short-circuit simulations in a test grid with adoption of the Brazilian grid code, without reactive power injection, being compared with those of other countries that adopt reactive power injection curves.
Between problems in the power grid expansions, distributed generation, energy market customers migrations, commercial losses and other problems, power distribution companies seek to improve both ...energy quality and costs reductions, enhancing profitability. A basic and crucial point for any energy company is how much energy to buy. That is, determining the amount of energy to be purchased as close as possible to that needed to serve its customers, avoiding financial losses by consuming more or less than they have. However, this is not a trivial problem, as energy consumption depends on several exogenous and endogenous factors, such as all the problems previously mentioned, in addition to economic, social, climatic, political and cultural aspects, among others. Thus, energy forecasts are realized with aid of both statistical analyzes and computational techniques. This article exposes a very short and short term energy forecast model using Neural Networks and feedback, applied in the new global context: the new coronavirus pandemic and its implications for energy consumption. The method was implemented with a real consumption dataset provided by the Brazilian energy company Equatorial from Para State and from Maranhao State. Very short term energy forecasts results reached a MAPE of around 1.2% in a 15-day window for both States, Para and Maranhao. For short term energy forecasts, results for both States were 3 possible scenarios in a window from June to December 2020, due to the unpredictability of the pandemic, especially in Brazil, which so far has shown no signs of reducing the contagion curve.
Genetic Algorithm (GA) is a non-parametric optimization technique that is frequently used in problems of combinatory nature with discrete or continuous variables. In treating with multi-objective ...evaluation functions it is important to have an adequate methodology to solve the multiple objectives problem so that each partial objective composing the evaluation function is adequately treated in the overall optimal solution. In this paper the multi-objective optimization problem is treated in details and a typical example concerning the allocation of capacitor banks in a real distribution grid is presented. The allocation of capacitor banks corresponds to one of the most important problems related to the planning of electrical distribution networks. This problem consists of determining, with the smallest possible cost, the placement and the dimension of each capacitor bank to be installed in the electrical distribution grid with the additional objectives of minimizing the voltage deviations and power losses. As many other problems of planning electrical distribution networks, the allocation of capacitor banks is characterized by the high complexity in the search of the optimum solution. In this context, the GA comes as a viable tool to obtaining practical solutions to this problem. Simulation results obtained with a real electrical distribution grid are presented and demonstrate the effectiveness of the methodology used.
To determine whether portoenterostomy (PE) revision in patients afflicted with biliary atresia (BA) is a viable treatment option and, if so, identify which patients may benefit.
BA, the most common ...cause of neonatal liver disease, results in biliary tract obstruction and hepatic fibrosis. Kasai PE is the initial surgical intervention performed and, if successful, restores drainage and preserves the native liver. Portoenterostomy failure warrants liver transplantation, but because of complications related to transplantation, treatment strategies to salvage the native liver may be beneficial. Using uniformly applied criteria, we have revised PEs to delay or avoid transplantation.
A retrospective review of medical records of patients diagnosed with BA since 1983 was performed. Patient demographics, symptoms, indications for revision, laboratory values, and outcomes were recorded. A cohort of patients who underwent revision after initial PE was identified. Survival rates were assessed using the Kaplan-Meier method. For patients who required transplantation, operative data from the revised PE cohort were compared with those from the unrevised PE cohort. A Cox proportional hazards model was used to determine covariates predictive of a favorable outcome.
Of 181 children who underwent PE, 24 underwent revision. Adequate biliary drainage, as evidenced by normalized conjugated bilirubin levels, was achieved in 75% of revised patients. Overall survival in patients who underwent revision, regardless of transplantation, was 87%. Among patients who underwent PE revision, 46% have survived with their native liver.
Experience at our center suggests that with appropriate patient selection, PE revision may delay the need for liver transplanation yielding encouraging patient outcomes.
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