► An efficient synthesis of substituted oxindoles with general applicability. ► Clay KSF effectively catalyzes the reactions using ultrasound irradiation. ► Methodology is superior in terms of scope, ...starting material availability, brevity, and reproducibility.
A simple facile, one-pot synthesis of oxindoles in reasonable purity is reported via intramolecular Friedal–Craft cyclization. Clay KSF is an inexpensive, efficient and mild catalyst for the synthesis of substituted oxindoles by the reaction of chloroacetyl chloride and various anilines under the influence of ultrasonic irradiation under solvent-free conditions. The remarkable advantages of this method are the simple experimental procedures, short reaction times, high yields of products, suitability for a wide variety of substituents, and the green aspects through the avoidance of toxic catalyst and solvents.
Staphylococcus aureus (S. aureus) is an important cause of bovine mastitis. The antiphagocytic capsule of bacteria promotes colonization and persistence on mucosal surfaces while the presence of ...collagen adhesin (cna gene) is associated with bacterial adhesion in mammary tissues; hence both are regarded as important determinants of virulence. In the present study, 197 samples consisting of mastitic milk, milkers' hand swabs and udder surface swabs were collected which yielded 107 S. aureus isolates. These S. aureus isolates (107) from different sources of sampling were characterized for their capsular types targeting cap5K and cap8K genes in a duplex PCR along with amplification of cna gene. Majority of the isolates (67.6%) possessed cap5K gene with a lower percentage (22.9%) of isolates carrying cap8K gene and 9.5% carrying both the genes. Moreover, cap5K gene was predominant in isolates from milkers’ hands (85.7%) while cap8K gene was more common in bovine udder isolates (41.2%). cna gene was observed in 27.6% isolates with highest occurrence in milk isolates (44.8%) compared to udder (37.9%) and milkers' hand (17.2%). cna positive isolates carried cap8K gene (66.7%) and were significantly associated with both cap5k and cap8k genes. In conclusion, the majority of the S. aureus isolates of mastitis obtained from arid and semi arid zones of India possessed the genes for capsule production, and cap5K was the predominant gene. The cna gene for collagen adhesion was observed in fewer isolates with significant association with cap8K gene.
The current study highlights the importance of a detailed representation of urban processes in numerical weather prediction models and emphasizes the need for accurate urban morphology data for ...improving the near‐surface weather prediction over Delhi, a tropical Indian city. The Met Office Reading Urban Surface Exchange Scheme (MORUSES), a two‐tile urban energy‐budget parameterization scheme, is introduced in a high‐resolution (330‐m) model of Delhi. A new empirical relationship is established for the MORUSES scheme from the local urban morphology of Delhi. The performance is evaluated using both the newly developed empirical relationships (MORUSES‐IND) and the existing empirical relationships for the MORUSES scheme (MORUSES‐LON) against the default one‐tile configuration (BEST‐1t) for clear and foggy events and validations are performed against ground observations. MORUSES‐IND exhibits a significant improvement in the diurnal evolution of the wind speed in terms of amplitude and phase, compared with the other two configurations. Screen temperature (Tscreen$$ {T}_{\mathrm{screen}} $$) simulations using MORUSES‐IND reduce the warm bias, especially during the evening and night hours. The root‐mean‐square error of Tscreen$$ {T}_{\mathrm{screen}} $$ is reduced up to 29% using MORUSES‐IND for both synoptic conditions. The diurnal cycle of surface‐energy fluxes is reproduced well using MORUSES‐IND. The net longwave fluxes are underestimated in the model and biases are more significant during foggy events, partly due to the misrepresentation of fog. An urban cool island (UCI) effect is observed in the early morning hours during clear‐sky conditions, but it is not evident on foggy days. Compared with BEST‐1t, MORUSES‐IND represents the impact of urbanization more realistically, which is reflected in the reduction of the urban heat island and UCI in both synoptic conditions. Future works would improve the coupling between the urban surface energy budget and anthropogenic aerosols by introducing MORUSES‐IND in a chemistry aerosol framework model.
Urban morphology parameters: (a) planar‐area index, (b) building height, and (c) frontal‐area index as a function of urban fraction derived from ISRO high‐resolution LULC data.
Nanocrystals of Cd
1−
x
Fe
x
S (
x
=
0–0.05) have been synthesized by aqueous solution precipitation method at room temperature. The effect of doping of Fe
2+ ions (0–0.05) on CdS compound ...semiconductor has been studied, using X-ray diffraction (XRD), optical absorption (UV–vis), photoluminescence (PL), and positron annihilation spectroscopy (PAS). The structure of these nanocrystals is found to be single phase hexagonal. Optical absorption is found to be decreased on increasing the Fe
2+ ions concentration. PL spectra are studied on most prominent excitation peaks within the wavelength range (586–731
nm). The emission intensities are found to be decreased on increasing Fe
2+ ions concentration. DC electrical conductivity is found to be increased on increasing Fe
2+ ions at room temperature. The Cd vacancy concentration decreases with increasing Fe concentration.
We present measurements of bulk properties of the matter produced in Au+Au collisions at $\sqrt{s}$$_ {NN}$= 7.7, 11.5, 19.6, 27, and 39 GeV using identified hadrons (π±, K±, p, and $\bar{p}$) from ...the STAR experiment in the Beam Energy Scan (BES) Program at the Relativistic Heavy Ion Collider (RHIC). Midrapidity (| y | < 0.1) results for multiplicity densities dN / dy, average transverse momenta $\langle$pT$\rangle$, and particle ratios are presented. The chemical and kinetic freeze-out dynamics at these energies are discussed and presented as a function of collision centrality and energy. These results constitute the systematic measurements of bulk properties of matter formed in heavy-ion collisions over a broad range of energy (or baryon chemical potential) at RHIC.
The extreme energy densities generated by ultra-relativistic collisions between heavy atomic nuclei produce a state of matter that behaves surprisingly like a fluid, with exceptionally high ...temperature and low viscosity. Non-central collisions have angular momenta of the order of 1,000ћ, and the resulting fluid may have a strong vortical structure that must be understood to describe the fluid properly. The vortical structure is also of particular interest because the restoration of fundamental symmetries of quantum chromodynamics is expected to produce novel physical effects in the presence of strong vorticity. However, no experimental indications of fluid vorticity in heavy ion collisions have yet been found. Since vorticity represents a local rotational structure of the fluid, spin-orbit coupling can lead to preferential orientation of particle spins along the direction of rotation. Here we present measurements of an alignment between the global angular momentum of a non-central collision and the spin of emitted particles (in this case the collision occurs between gold nuclei and produces Λ baryons), revealing that the fluid produced in heavy ion collisions is the most vortical system so far observed. (At high energies, this fluid is a quark-gluon plasma.) We find that Λ and hyperons show a positive polarization of the order of a few per cent, consistent with some hydrodynamic predictions. (A hyperon is a particle composed of three quarks, at least one of which is a strange quark; the remainder are up and down quarks, found in protons and neutrons.) A previous measurement that reported a null result, that is, zero polarization, at higher collision energies is seen to be consistent with the trend of our observations, though with larger statistical uncertainties. These data provide experimental access to the vortical structure of the nearly ideal liquid created in a heavy ion collision and should prove valuable in the development of hydrodynamic models that quantitatively connect observations to the theory of the strong force.
The Λ (Λ¯) hyperon polarization along the beam direction has been measured in Au+Au collisions at sNN=200 GeV, for the first time in heavy-ion collisions. The polarization dependence on the ...hyperons' emission angle relative to the elliptic flow plane exhibits a second harmonic sine modulation, indicating a quadrupole pattern of the vorticity component along the beam direction, expected due to elliptic flow. The polarization is found to increase in more peripheral collisions, and shows no strong transverse momentum (pT) dependence at pT greater than 1 GeV/c. The magnitude of the signal is about 5 times smaller than those predicted by hydrodynamic and multiphase transport models; the observed phase of the emission angle dependence is also opposite to these model predictions. In contrast, the kinematic vorticity calculations in the blast-wave model tuned to reproduce particle spectra, elliptic flow, and the azimuthal dependence of the Gaussian source radii measured with the Hanbury Brown–Twiss intensity interferometry technique reproduce well the modulation phase measured in the data and capture the centrality and transverse momentum dependence of the polarization signal.
Throughout Asian countries including India
,
water buffalo
(Bubalus bubalis)
plays a crucial role in socio-economic status of the farmers by providing nutritional security. The concept of genomic ...selection through genetic markers has been widely used in various livestock species and this is extended to buffalo species as well. Molecular markers have been extensively used in animal breeding for improvements of desirable animal traits. Single Nucleotide Polymorphism (SNP), one of the important molecular markers is widely used in animal breeding program. In this study, SNPs related to four important traits of buffalo i.e., milk volume, age at first calving, post-partum cyclicity and feed conversion efficiency have been identified based on genome sequence data generated using ddRAD (double digest Restriction-site Associated DNA) sequencing technology. These identified SNPs have been compiled as database accessible through Web and can be used in molecular breeding program of buffalo species. This database facilitates easy search of SNPs, Polymorphic Loci and Haplotypes along with their important features like minor and major allele frequencies, observed and expected heterozygosity, observed and expected homozygosity and nucleotide diversity. This database will help to accelerate the molecular breeding program for developing trait specific breeds of buffalo to meet the need of food and nutritional security of the world including India.
Global polarization of Λ hyperons has been measured to be of the order of a few tenths of a percent in Au+Au collisions at √SNN = 200 GeV, with no significant difference between Λ and Λ¯. These new ...results reveal the collision energy dependence of the global polarization together with the results previously observed √SNN = 7.7 – 62.4 GeV and indicate noticeable vorticity of the medium created in non-central heavy-ion collisions at the highest RHIC collision energy.
At sufficiently high temperature and energy density, nuclear matter undergoes a transition to a phase in which quarks and gluons are not confined: the quark-gluon plasma (QGP). Such an exotic state ...of strongly interacting quantum chromodynamics matter is produced in the laboratory in heavy nuclei high-energy collisions, where an enhanced production of strange hadrons is observed. Strangeness enhancement, originally proposed as a signature of QGP formation in nuclear collisions, is more pronounced for multi-strange baryons. Several effects typical of heavy-ion phenomenology have been observed in high-multiplicity proton-proton (pp) collisions, but the enhanced production of multi-strange particles has not been reported so far. Here we present the first observation of strangeness enhancement in high-multiplicity proton-proton collisions. We find that the integrated yields of strange and multi-strange particles, relative to pions, increases significantly with the event charged-particle multiplicity. The measurements are in remarkable agreement with the p-Pb collision results, indicating that the phenomenon is related to the final system created in the collision. In high-multiplicity events strangeness production reaches values similar to those observed in Pb-Pb collisions, where a QGP is formed.
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