Aims. The purpose of this work is the characterization of the radial distribution of dust, stars, gas, and star-formation rate (SFR) in a sub-sample of 18 face-on spiral galaxies extracted from the ...DustPedia sample. Methods. This study is performed by exploiting the multi-wavelength DustPedia database, from ultraviolet (UV) to sub-millimeter bands, in addition to molecular (12CO) and atomic (Hi) gas maps and metallicity abundance information available in the literature. We fitted the surface-brightness profiles of the tracers of dust and stars, the mass surface-density profiles of dust, stars, molecular gas, and total gas, and the SFR surface-density profiles with an exponential curve and derived their scale-lengths. We also developed a method to solve for the CO-to-H2 conversion factor (αCO) per galaxy by using dust- and gas-mass profiles. Results. Although each galaxy has its own peculiar behavior, we identified a common trend of the exponential scale-lengths versus wavelength. On average, the scale-lengths normalized to the B-band 25 mag/arcsec2 radius decrease from UV to 70 μm, from 0.4 to 0.2, and then increase back up to ~0.3 at 500 microns. The main result is that, on average, the dust-mass surface-density scale-length is about 1.8 times the stellar one derived from IRAC data and the 3.6 μm surface brightness, and close to that in the UV. We found a mild dependence of the scale-lengths on the Hubble stage T: the scale-lengths of the Herschel bands and the 3.6 μm scale-length tend to increase from earlier to later types, the scale-length at 70 μm tends to be smaller than that at longer sub-mm wavelength with ratios between longer sub-mm wavelengths and 70 μm that decrease with increasing T. The scale-length ratio of SFR and stars shows a weak increasing trend towards later types. Our αCO determinations are in the range (0.3−9) M⊙ pc-2 (K km s-1)-1, almost invariant by using a fixed dust-to-gas ratio mass (DGR) or a DGR depending on metallicity gradient.
Aims. The DustPedia project is capitalising on the legacy of the Herschel Space Observatory, using cutting-edge modelling techniques to study dust in the 875 DustPedia galaxies – representing the ...vast majority of extended galaxies within 3000 km s-1 that were observed by Herschel. This work requires a database of multiwavelength imagery and photometry that greatly exceeds the scope (in terms of wavelength coverage and number of galaxies) of any previous local-Universe survey. Methods. We constructed a database containing our own custom Herschel reductions, along with standardised archival observations from GALEX, SDSS, DSS, 2MASS, WISE, Spitzer, and Planck. Using these data, we performed consistent aperture-matched photometry, which we combined with external supplementary photometry from IRAS and Planck. Results. We present our multiwavelength imagery and photometry across 42 UV-microwave bands for the 875 DustPedia galaxies. Our aperture-matched photometry, combined with the external supplementary photometry, represents a total of 21 857 photometric measurements. A typical DustPedia galaxy has multiwavelength photometry spanning 25 bands. We also present the Comprehensive & Adaptable Aperture Photometry Routine (CAAPR), the pipeline we developed to carry out our aperture-matched photometry. CAAPR is designed to produce consistent photometry for the enormous range of galaxy and observation types in our data. In particular, CAAPR is able to determine robust cross-compatible uncertainties, thanks to a novel method for reliably extrapolating the aperture noise for observations that cover a very limited amount of background. Our rich database of imagery and photometry is being made available to the community.
Aims.
The purpose of this work is the characterization of the main scaling relations between all of the interstellar medium (ISM) components, namely dust, atomic, molecular, and total gas, and ...gas-phase metallicity, as well as other galaxy properties, such as stellar mass (
M
star
) and galaxy morphology, for late-type galaxies in the Local Universe.
Methods.
This study was performed by extracting late-type galaxies from the entire DustPedia sample and by exploiting the large and homogeneous dataset available thanks to the DustPedia project. The sample consists of 436 galaxies with morphological stage spanning from
T
= 1−10,
M
star
from 6 × 10
7
to 3 × 10
11
M
⊙
, star formation rate from 6 × 10
−4
to 60
M
⊙
yr
−1
, and oxygen abundance from 12 + log(O/H) = 8−9.5. Molecular and atomic gas data were collected from the literature and properly homogenized. All the masses involved in our analysis refer to the values within the optical disks of galaxies. The scaling relations involving the molecular gas are studied by assuming both a constant and a metallicity-dependent CO-to-H
2
conversion factor (
X
CO
). The analysis was performed by means of the survival analysis technique, in order to properly take into account the presence of both detection and nondetection in the data.
Results.
We confirm that the dust mass correlates very well with the total gas mass, and find –for the first time– that the dust mass correlates better with the atomic gas mass than with the molecular one. We characterize important mass ratios such as the gas fraction, the molecular-to-atomic gas mass ratio, the dust-to-total gas mass ratio (DGR), and the dust-to-stellar mass ratio, and study how they relate to each other, to galaxy morphology, and to gas-phase metallicity. Only the assumption of a metallicity-dependent
X
CO
reproduces the expected decrease of the DGR with increasing morphological stage and decreasing gas-phase metallicity, with a slope of about 1. The DGR, the gas-phase metallicity, and the dust-to-stellar mass ratio are, for our galaxy sample, directly linked to galaxy morphology. The molecular-to-atomic gas mass ratio and the DGR show a positive correlation for low molecular gas fractions, but for galaxies rich in molecular gas this trend breaks down. To our knowledge, this trend has never been found before, and provides new constraints for theoretical models of galaxy evolution and a reference for high-redshift studies. We discuss several scenarios related to this finding.
Conclusions.
The DustPedia database of late-type galaxies is an extraordinary tool for the study of the ISM scaling relations, thanks to its homogeneous collection of data for the different ISM components. The database is made publicly available to the whole community.
Observations of evolution in the dust-to-metal ratio allow us to constrain the dominant dust processing mechanisms. In this work, we present a study of the dust-to-metal and dust-to-gas ratios in a ...sub-sample of ~500 DustPedia galaxies. Using literature and MUSE emission line fluxes, we derived gas-phase metallicities (oxygen abundances) for over 10 000 individual regions and determine characteristic metallicities for each galaxy. We study how the relative dust, gas, and metal contents of galaxies evolve by using metallicity and gas fraction as proxies for evolutionary state. The global oxygen abundance and nitrogen-to-oxygen ratio are found to increase monotonically as galaxies evolve. Additionally, unevolved galaxies (gas fraction >60%, metallicity 12 + log(O∕H) < 8.2) have dust-to-metal ratios that are about a factor of 2.1 lower (a factor of six lower for galaxies with gas fraction >80%) than the typical dust-to-metal ratio (Md∕MZ ~ 0.214) for more evolved sources. However, for high gas fractions, the scatter is larger due to larger observational uncertainties as well as a potential dependence of the dust grain growth timescale and supernova dust yield on local conditions and star formation histories. We find chemical evolution models with a strong contribution from dust grain growth describe these observations reasonably well. The dust-to-metal ratio is also found to be lower for low stellar masses and high specific star formation rates (with the exception of some sources undergoing a starburst). Finally, the metallicity gradient correlates weakly with the HI-to-stellar mass ratio, the effective radius and the dust-to-stellar mass ratio, but not with stellar mass.
The clinical use of cisplatin (cis-diamminedichloroplatinum II) is highly limited by its nephrotoxicity. The precise mechanisms involved in cisplatin-induced mitochondrial dysfunction in kidney have ...not been completely clarified. Therefore, we investigated in vivo the effects of cisplatin on mitochondrial bioenergetics, redox state, and oxidative stress as well as the occurrence of cell death by apoptosis in cisplatin-treated rat kidney. Adult male Wistar rats weighing 200-220 g were divided into two groups. The control group (n = 8) was treated only with an intraperitoneal (i.p.) injection of saline solution (1 ml per 100 g body weight), and the cisplatin group (n = 8) was given a single injection of cisplatin (10 mg/kg body weight, i.p.). Animals were sacrificed 72 h after the treatment. The cisplatin group presented acute renal failure characterized by increased plasmatic creatinine and urea levels. Mitochondrial dysfunction was evidenced by the decline in membrane electrochemical potential and the substantial decrease in mitochondrial calcium uptake. The mitochondrial antioxidant defense system was depleted, as shown by decreased GSH and NADPH levels, GSH/GSSG ratio, and increased GSSG level. Moreover, cisplatin induced oxidative damage to mitochondrial lipids, including cardiolipin, and oxidation of mitochondrial proteins, as demonstrated by the significant decrease of sulfhydryl protein concentrations and increased levels of carbonylated proteins. Additionally, aconitase activity, which is essential for mitochondrial function, was also found to be lower in the cisplatin group. Renal cell death via apoptosis was evidenced by the increased caspase-3 activity. Results show the central role of mitochondria and the intensification of apoptosis in cisplatin-induced acute renal failure, highlighting a number of steps that might be targeted to minimize cisplatin-induced nephrotoxicity.
Nephrotoxicity is the major dose-limiting factor of cisplatin chemotherapy. Reactive oxygen species generated in mitochondria are thought to be the main cause of cellular damage in such injury. The ...present study examined, in vivo, the protective potential of the hydroxyl radical scavenger dimethylthiourea (DMTU) against cisplatin-induced effects on renal mitochondrial bioenergetics, redox state and oxidative stress. Adult male Wistar rats (200 to 220 g) were divided into four groups of eight animals each. The control group was treated only with an intraperitoneal (i.p.) injection of saline solution (1 ml/100 g body weight). The second group was given only DMTU (500 mg/kg body weight, i.p, followed by 125 mg/Kg, i.p., twice a day until they were killed). The third group was given a single injection of cisplatin (10 mg/kg body weight, i.p.). The fourth group was given DMTU (500 mg/kg body weight, i.p.), just before the cisplatin injection (10 mg/kg body weight, i.p.), followed by injections of DMTU (125 mg/kg body weight, i.p.) twice a day until they were killed. Animals were killed 72 h after the treatment. Besides not presenting any direct effect on mitochondria, DMTU substantially inhibited cisplatin-induced mitochondrial injury and cellular death by apoptosis, suppressing the occurrence of acute renal failure. All the following cisplatin-induced effects were prevented by DMTU: (1) increased plasmatic levels of creatinine and blood urea nitrogen (BUN); (2) decreased ATP content, calcium uptake and electrochemical potential; (3) oxidation of lipids, including cardiolipin; and oxidation of proteins, including sulfhydryl, and aconitase enzyme, as well as accumulation of carbonyl proteins; (4) depletion of the antioxidant defense (NADPH and GSH) and (5) increased activity of the apoptosis executioner caspase-3. Our findings show the important role played by mitochondria and hydroxyl radicals in cisplatin-induced nephrotoxicity, as well as the effectiveness of DMTU in preventing the renal mitochondrial damage caused by cisplatin. These results strongly suggest that protection of mitochondria by hydroxyl radical scavengers may be an interesting approach to prevent the kidney tissue damage caused by cisplatin-chemotherapy.
Aims. We aim to study the fraction of stellar radiation absorbed by dust, fabs, in 814 galaxies of different morphological types. The targets constitute the vast majority (93%) of the DustPedia ...sample, including almost all large (optical diameter larger than 1′), nearby (v ≤ 3000 km s−1) galaxies observed with the Herschel Space Observatory. Methods. For each object, we modelled the spectral energy distribution from the ultraviolet to the sub-millimetre using the dedicated, aperture-matched DustPedia photometry and the Code Investigating GALaxy Evolution (CIGALE). The value of fabs was obtained from the total luminosity emitted by dust and from the bolometric luminosity, which are estimated by the fit. Results. On average, 19% of the stellar radiation is absorbed by dust in DustPedia galaxies. The fraction rises to 25% if only late-type galaxies are considered. The dependence of fabs on morphology, showing a peak for Sb-Sc galaxies, is weak; it reflects a stronger, yet broad, positive correlation with the bolometric luminosity, which is identified for late-type, disk-dominated, high-specific-star-formation rate, gas-rich objects. We find no variation of fabs with inclination, at odds with radiative transfer models of edge-on galaxies. These results call for a self-consistent modelling of the evolution of the dust mass and geometry along the build-up of the stellar content. We also provide template spectral energy distributions in bins of morphology and luminosity and study the variation of fabs with stellar mass and specific star-formation rate. We confirm that the local Universe is missing the high fabs, luminous and actively star-forming objects necessary to explain the energy budget in observations of the extragalactic background light.
ABSTRACT
The dust mass absorption coefficient, κd is the conversion function used to infer physical dust masses from observations of dust emission. However, it is notoriously poorly constrained, and ...it is highly uncertain how it varies, either between or within galaxies. Here we present the results of a proof-of-concept study, using the DustPedia data for two nearby face-on spiral galaxies M 74 (NGC 628) and M 83 (NGC 5236), to create the first ever maps of κd in galaxies. We determine κd using an empirical method that exploits the fact that the dust-to-metals ratio of the interstellar medium is constrained by direct measurements of the depletion of gas-phase metals. We apply this method pixel-by-pixel within M 74 and M 83, to create maps of κd. We also demonstrate a novel method of producing metallicity maps for galaxies with irregularly sampled measurements, using the machine learning technique of Gaussian process regression. We find strong evidence for significant variation in κd. We find values of κd at 500 $\mu$m spanning the range 0.11–0.25 ${\rm m^{2}\, kg^{-1}}$ in M 74, and 0.15–0.80 ${\rm m^{2}\, kg^{-1}}$ in M 83. Surprisingly, we find that κd shows a distinct inverse correlation with the local density of the interstellar medium. This inverse correlation is the opposite of what is predicted by standard dust models. However, we find this relationship to be robust against a large range of changes to our method – only the adoption of unphysical or highly unusual assumptions would be able to suppress it.
Most radiative transfer models assume that dust in spiral galaxies is distributed exponentially. In this paper our goal is to verify this assumption by analysing the two-dimensional large-scale ...distribution of dust in galaxies from the DustPedia sample. For this purpose, we have made use of Herschel imaging in five bands, from 100 to 500 μm, in which the cold dust constituent is primarily traced and makes up the bulk of the dust mass in spiral galaxies. For a subsample of 320 disc galaxies, we successfully performed a simultaneous fitting with a single Sérsic model of the Herschel images in all five bands using the multi-band modelling code GALFITM. We report that the Sérsic index n, which characterises the shape of the Sérsic profile, lies systematically below 1 in all Herschel bands and is almost constant with wavelength. The average value at 250 μm is 0.67 ± 0.37 (187 galaxies are fitted with n250 ≤ 0.75, 87 galaxies have 0.75 < n250 ≤ 1.25, and 46 – with n250 > 1.25). Most observed profiles exhibit a depletion in the inner region (at r < 0.3−0.4 of the optical radius r25) and are more or less exponential in the outer part. We also find breaks in the dust emission profiles at longer distances (0.5−0.6) r25 which are associated with the breaks in the optical and near-infrared. We assumed that the observed deficit of dust emission in the inner galaxy region is related to the depression in the radial profile of the HI surface density in the same region because the atomic gas reaches high enough surface densities there to be transformed into molecular gas. If a galaxy has a triggered star formation in the inner region (for example, because of a strong bar instability, which transfers the gas inwards to the centre, or a pseudobulge formation), no depletion or even an excess of dust emission in the centre is observed.
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