We present a community data set of daily forcing and hydrologic response data for 671 small- to medium-sized basins across the contiguous United States (median basin size of 336 km2) that spans a ...very wide range of hydroclimatic conditions. Area-averaged forcing data for the period 1980-2010 was generated for three basin spatial configurations - basin mean, hydrologic response units (HRUs) and elevation bands - by mapping daily, gridded meteorological data sets to the subbasin (Daymet) and basin polygons (Daymet, Maurer and NLDAS). Daily streamflow data was compiled from the United States Geological Survey National Water Information System. The focus of this paper is to (1) present the data set for community use and (2) provide a model performance benchmark using the coupled Snow-17 snow model and the Sacramento Soil Moisture Accounting Model, calibrated using the shuffled complex evolution global optimization routine. After optimization minimizing daily root mean squared error, 90% of the basins have Nash-Sutcliffe efficiency scores greater than or equal to 0.55 for the calibration period and 34% greater than or equal to 0.8. This benchmark provides a reference level of hydrologic model performance for a commonly used model and calibration system, and highlights some regional variations in model performance. For example, basins with a more pronounced seasonal cycle generally have a negative low flow bias, while basins with a smaller seasonal cycle have a positive low flow bias. Finally, we find that data points with extreme error (defined as individual days with a high fraction of total error) are more common in arid basins with limited snow and, for a given aridity, fewer extreme error days are present as the basin snow water equivalent increases.
The federal government pays benefits to coal miners affected by coal workers' pneumoconiosis (CWP, commonly referred to as black lung disease) and other lung diseases linked to coal mining in cases ...where responsible mine operators are not able to pay. This book looks at the Mine Safety and Health Administration's coal dust rules and provides background information and policy options concerning the Black Lung Disability Trust Fund.
Five-part invention Blodgett, E. D
Five-part invention,
c2003, 20030205, 2003, 2014, 2003-01-01
eBook
Blodgett suggests that each of the several 'national' groups that compose Canada develops unique narratives that demonstrate their different responses to the notion of nationhood and their sense of ...place within Canada?s borders.
Gossypol, a pigment of cotton, is a hepatic toxin for chickens. Thus, despite its high protein content, inclusion of cottonseed meal in poultry diets is problematic. Silymarin, an extract from milk ...thistle, has hepatoprotective qualities and could potentially serve as a feed additive to offset the toxicity of gossypol. The objective of this study was to determine if silymarin could counteract gossypol toxicosis. Cockerels (n = 144) from lines divergently selected for humoral immunity were used. Three individuals from each line were randomly assigned to a cage and fed a corn-soybean meal (control) diet for 14 d. Six cages per line were then randomly assigned 1 of 4 dietary treatments (1,000 mg/kg of gossypol, 1,000 mg/kg of silymarin, 1,000 mg/kg of both gossypol and silymarin, or a control diet). Body weight and feed intake data were collected for 21 d, with chickens bled weekly to collect plasma and determine hematocrits. Chickens were then killed, and livers were collected for subsequent histology and enzymatic activity analyses. Endpoints measured weekly were analyzed with repeated measures and regression methodologies. Plasma and liver enzyme activities, and histological measures, were analyzed using ANOVA. No significant interactions between diets and lines were observed. Chickens assigned to the gossypol and gossypol-silymarin diets stopped gaining weight at d 14 (P < 0.001) and lost weight by d 21 (P < 0.001). Gamma glutamyltransferase was also elevated in these chickens at d 14; activities increased further by d 21 (P < 0.001). Histological examination of liver slices indicated substantial lipidosis (P < 0.001). Furthermore, quinone reductase activity was higher in gossypol- and gossypol-silymarin-treated chickens than in control and silymarin-treated chickens (P < 0.001). Silymarin did not alleviate any clinical effects of gossypol toxicosis.
Liver enzymes are essential to xenobiotic metabolism. Expression of these enzymes is dependent upon factors such as age and sex. The objective of this study was to determine basal liver enzyme levels ...in male and female White Leghorn chickens to provide reference values for future studies. Chickens from 2 lines divergently selected for 35 generations for high antibody and low antibody immune response to SRBC were used. Six male and 6 female chickens from each line were killed at each of 4, 8, 12, and 20 wk of age. Livers were collected and used for enzyme analyses. Liver tissue was analyzed for quinone reductase, glutathione-S-transferase, and cytochrome P450 3A4 activity. All data were analyzed using ANOVA. There were no consistent differences in enzyme activity between high- and low-antibody lines at any age. Cytochrome P450 3A4 activity was substantially greater in 4- and 8-wk than in 12- and 20-wk-old chickens (P < 0.001). This study provides insights into enzyme activities of liver enzymes; however, except for cytochrome P450 3A4, no clear trends across ages were observed.
Poems for a small park Blodgett, E. D
Poems for a small park,
c2008, 2008, 2014, 2008-12-01
eBook
Odprti dostop
Blodgett wrote his poems for a small park in English and some in French, but was able to have some of them translated into Cree, Michif, Chinese, and Ukrainian. This reflects Edmonton’s unique ...multicultural ambience and the roles of diverse cultures in the making of the city. The powerful images and thoughtful metaphors in these short lyrics show readers the connections between Canadian nature (even within city limits) and the sublime, especially in the overwhelming silence we can sense outdoors – if we pay attention. The poet speaks to change by helping us see natural phenomena around us in a different light each time we read his poems
Dental health care and research workers require a means of imaging the structures within teeth in vivo. For example, there is a need to image the margins of a restoration for the detection of poor ...bonding or voids between the restorative material and the dentin. In addition, a high-resolution imaging modality is needed to detect tooth decay in its early stages. If decay can be detected early enough, the process can be monitored and interventional procedures, such as fluoride washes and controlled diet, can be initiated to help remineralize the tooth. Currently employed x-ray imaging is limited in its ability to visualize interfaces and incapable of detecting decay at a stage early enough to avoid invasive cavity preparation followed by a restoration. To this end, nondestructive and noncontact in vitro measurements on "as-is" extracted sections of human incisors and molars using laser-based ultrasonics are presented. Broadband ultrasonic waves are excited in the extracted sections by using a pulsed carbon-dioxide (CO2) laser operating in a region of high optical absorption in the dental hard tissues. Optical interferometric detection of the ultrasonic wave surface displacements is accomplished with a path-stabilized Michelson-type interferometer. Laser ultrasonics is found effective in characterizing the anisotropic and inhomogeneous nature of dentin. In addition, time-of-flight analysis of the measured bulk transmission waveforms allows for detection of dentino-enamel and carious dentin-dentin junctions. These results are compared to those obtained for specially prepared tooth phantoms that mimic the mechanical properties of dental hard tissues.
A grazing experiment was conducted to assess the effects of wild-type endophyte-infected (E+) tall fescue consumption and elevated ambient temperatures on intravaginal temperatures, plasma lipid ...peroxidation, and glutathione redox of peripheral blood mononuclear cells. Angus heifers (n = 34) were allotted by BW to 4 blocks consisting of E+ and endophyte-free (E-) fescue pastures. Monthly, in June, July, and August, temperature loggers were fixed into blank controlled internal drug releasers and inserted into a subsample of heifers (n = 16) for 2 d. After 48 h, heifers were weighed, and blood (30 mL) was collected via jugular venipuncture. Peripheral blood mononuclear cells were isolated for analysis of glutathione peroxidase activity, glutathione reductase activity, and reduced:oxidized glutathione. Plasma malondialdehyde was evaluated as a marker of lipid peroxidation, and whole blood Se concentration was determined. Serum prolactin was assayed after the grazing period. Heifer ADG was greatest in August and least in July (P < 0.001). In August, heifers grazing E+ fescue exhibited greater (P < 0.05) afternoon intravaginal temperatures and temperature fluctuations than heifers grazing E- fescue. In July and August, all heifers had greater afternoon temperatures (P < 0.02) and less reduced:oxidized glutathione (P < 0.0001) than in June. Glutathione reductase activity of all heifers was greater in June (P = 0.03) than in July. Similarly, all heifers exhibited decreased glutathione peroxidase activity (P < 0.0008) in July, whereas whole blood Se was reduced (P < 0.0001) in July and August. No treatment or date effects were detected for malondialdehyde, but serum prolactin was reduced at the end of the grazing period (P = 0.008) in heifers stocked on E+ fescue. Using these markers, differences in oxidative stress were not detected between heifers consuming E+ fescue and those consuming E- fescue. Date effects indicating altered glutathione redox and enzyme activity may have been related to heat stress and nutritional limitations.
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