In 2019, the Research and Education Collaborative Occultation Network (RECON) obtained multiple-chord occultation measurements of two Centaur objects: 2014 YY49 on 2019 January 28 and 2013 NL24 on ...2019 September 4. RECON is a citizen-science telescope network designed to observe high-uncertainty occultations by outer solar system objects. Adopting circular models for the object profiles, we derive a radius km and a geometric albedo for 2014 YY49 and a radius km and a geometric albedo for 2013 NL24. To the precision of these measurements, no atmosphere or rings are detected for either object. The two objects measured here are among the smallest distant objects measured with the stellar occultation technique. In addition to these geometric constraints, the occultation measurements provide astrometric constraints for these two Centaurs at a higher precision than has been feasible by direct imaging. To supplement the occultation results, we also present an analysis of color photometry from the Pan-STARRS surveys to constrain the rotational light curve amplitudes and spectral colors of these two Centaurs. We recommend that future work focus on photometry to more deliberately constrain the objects' colors and light curve amplitudes and on follow-on occultation efforts informed by this astrometry.
Full disclosure: I operate in both worlds, publishing my sacred/church anthems with Beckenhorst Press (where I also serve as vice president of publications and editor) but self-publishing my concert ...choral works through The Music of Dan Forrest. According to Kathy Fernandes, Pepper's Chief Sales and Marketing Officer: We witness the benefits publishers provide composers as good stewards of their works. ...getting "noticed" as a self-publisher may be just as difficult as getting accepted by a traditional publisher. Traditional publishers carefully choose the pieces they believe are most likely to succeed, which generally holds composers to a higher standard and helps reduce "flooding the market."
We report on the stellar occultation by (523764) 2014 WC510 observed on 2018 December 1 UT. This occultation campaign was part of the Research and Education Collaborative Occultation Network (RECON), ...a network of small telescopes spread over 2000 km in western USA and Canada. Light curves from six stations revealed three groups of two or more consecutive flux drops correlated in time between adjacent stations. A Bayesian model comparison reveals that a model with a double object occulting a double star is favored over alternative models considered. For the statistically favored model, we determined that the primary component of the object has a diameter dp = 181 16 km and the secondary ds = 138 32 km, assuming identical geometric albedo between the two components. The two components have a projected separation of 349 26 km. Adopting an absolute magnitude for the system of HV = 7.2 from the Minor Planet Center, we derive a geometric albedo of pV = 5.1% 1.7%. This is the smallest resonant object with an occultation size measurement and with a detected secondary from a ground-based stellar occultation, filling a region of the size versus separation parameter space of binary objects that is largely unexplored. The results show the capabilities of the unique design of the RECON experiment sensitive to small objects and close binaries. 2014 WC510 is presently at a low galactic latitude where the high surface density of stars will provide good occultation opportunities in the upcoming years.
Abstract
In 2019, the Research and Education Collaborative Occultation Network (RECON) obtained multiple-chord occultation measurements of two Centaur objects: 2014 YY
49
on 2019 January 28 and 2013 ...NL
24
on 2019 September 4. RECON is a citizen-science telescope network designed to observe high-uncertainty occultations by outer solar system objects. Adopting circular models for the object profiles, we derive a radius
km and a geometric albedo
for 2014 YY
49
and a radius
km and a geometric albedo
for 2013 NL
24
. To the precision of these measurements, no atmosphere or rings are detected for either object. The two objects measured here are among the smallest distant objects measured with the stellar occultation technique. In addition to these geometric constraints, the occultation measurements provide astrometric constraints for these two Centaurs at a higher precision than has been feasible by direct imaging. To supplement the occultation results, we also present an analysis of color photometry from the Pan-STARRS surveys to constrain the rotational light curve amplitudes and spectral colors of these two Centaurs. We recommend that future work focus on photometry to more deliberately constrain the objects’ colors and light curve amplitudes and on follow-on occultation efforts informed by this astrometry.
In 2019, the Research and Education Collaborative Occultation Network (RECON) obtained multiple-chord occultation measurements of two centaur objects: 2014 YY\(_{49}\) on 2019 January 28 and 2013 ...NL\(_{24}\) on 2019 September 4. RECON is a citizen-science telescope network designed to observe high-uncertainty occultations by outer solar system objects. Adopting circular models for the object profiles, we derive a radius \(r=16^{+2}_{-1}\)km and a geometric albedo \(p_V=0.13^{+0.015}_{-0.024}\) for 2014 YY\(_{49}\), and a radius \(r=66 ^{+5}_{-5}\)km and geometric albedo \(p_V = 0.045^{+0.006}_{-0.008}\) for 2013 NL\(_{24}\). To the precision of these measurements, no atmosphere or rings are detected for either object. The two objects measured here are among the smallest distant objects measured with the stellar occultation technique. In addition to these geometric constraints, the occultation measurements provide astrometric constraints for these two centaurs at a higher precision than has been feasible by direct imaging. To supplement the occultation results, we also present an analysis of color photometry from the Pan-STARRS surveys to constrain the rotational light curve amplitudes and spectral colors of these two centaurs. We recommend that future work focus on photometry to more deliberately constrain the objects' colors and light curve amplitudes, and on follow-on occultation efforts informed by this astrometry.
With the wide availability of digital content and proliferation of Web2.0 applications, supporting secure and efficient identification of digital content becomes a more and more important issue. In ...early 2010, the Open Mobile Alliance (OMA) ratified a new standard known as Secure Content IDentification Mechanism (SCIDM) to facilitate the management of digital content. As the main contributors to the SCIDM standard, the authors provide an overview of this standard as well as a use case in this paper.
Through their many and varied metabolic functions, mitochondria power life. Paradoxically, mitochondria also have a central role in apoptotic cell death. Upon induction of mitochondrial apoptosis, ...mitochondrial outer membrane permeabilization (MOMP) usually commits a cell to die. Apoptotic signalling downstream of MOMP involves cytochrome c release from mitochondria and subsequent caspase activation. As such, targeting MOMP in order to manipulate cell death holds tremendous therapeutic potential across different diseases, including neurodegenerative diseases, autoimmune disorders and cancer. In this Review, we discuss new insights into how mitochondria regulate apoptotic cell death. Surprisingly, recent data demonstrate that besides eliciting caspase activation, MOMP engages various pro-inflammatory signalling functions. As we highlight, together with new findings demonstrating cell survival following MOMP, this pro-inflammatory role suggests that mitochondria-derived signalling downstream of pro-apoptotic cues may also have non-lethal functions. Finally, we discuss the importance and roles of mitochondria in other forms of regulated cell death, including necroptosis, ferroptosis and pyroptosis. Collectively, these new findings offer exciting, unexplored opportunities to target mitochondrial regulation of cell death for clinical benefit.
Prior research has shown that U.S. cultures of honor have higher rates of depression and suicide. While links between honor endorsement and suicide have been established in the literature, a direct ...test of the primary mechanism underlying this association (reputation damage leading to depression) has not yet been tested. The current study sought to address whether shifts in perceived reputation might be associated with higher levels of depression for honor endorsing individuals. An online sample of 305 participants were tracked across two time points, assessing perceived individual reputation and perceived family reputation, as well as depressive symptoms. Analyses revealed that higher levels of honor concern at Time 1 were linked with higher levels of depressive symptoms at Time 2, but only for those with low perceived reputation - these relationships held while controlling for the stability in reputation and depression across time points, as well as controlling for participants' gender. Findings provide the first empirical evidence that reputation damage may contribute to detriments in mental health in honor endorsers.
Cardiorenal Syndrome: New Perspectives BOCK, Jeremy S; GOTTLIEB, Stephen S
Circulation (New York, N.Y.),
06/2010, Letnik:
121, Številka:
23
Journal Article
Damaged or superfluous cells are typically eliminated by apoptosis. Although apoptosis is a cell-autonomous process, apoptotic cells communicate with their environment in different ways. Here we ...describe a mechanism whereby cells under apoptotic stress can promote survival of neighbouring cells. We find that upon apoptotic stress, cells release the growth factor FGF2, leading to MEK-ERK-dependent transcriptional upregulation of pro-survival BCL-2 proteins in a non-cell autonomous manner. This transient upregulation of pro-survival BCL-2 proteins protects neighbouring cells from apoptosis. Accordingly, we find in certain cancer types a correlation between FGF-signalling, BCL-2 expression and worse prognosis. In vivo, upregulation of MCL-1 occurs in an FGF-dependent manner during skin repair, which regulates healing dynamics. Importantly, either co-treatment with FGF-receptor inhibitors or removal of apoptotic stress restores apoptotic sensitivity to cytotoxic therapy and delays wound healing. These data reveal a pathway by which cells under apoptotic stress can increase resistance to cell death in surrounding cells. Beyond mediating cytotoxic drug resistance, this process also provides a potential link between tissue damage and repair.
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