Context. Aims. We derive rotation curves from optical emission lines of 182 disc galaxies (96 in the cluster and 86 in the field) in the region of Abell 901/902 located at z ~ 0.165. We continue the ...kinematic analysis presented in a previous paper. Here, we focus on the analysis of B-band and stellar-mass Tully-Fisher relations. We examine possible environmental dependencies and differences between normal spirals and dusty red galaxies, i.e. disc galaxies that have red colours because of relatively low star formation rates. Methods. Assuming a tilted ring model we simulate the spectroscopy of a given galaxy and reconstruct the maximum rotation velocity from the best-fitting simulated rotation curve. We fit regression lines adopting a maximum-likelihood method based on Bayes’ theorem to build B-band and stellar-mass Tully-Fisher relations. Results. We find no significant differences between the best-fit Tully-Fisher slope of cluster and field galaxies. At fixed slope, the field population with high-quality rotation curves (57 objects) is brighter by ΔMB = −0.m42 ± 0.m15 than the cluster population (55 objects). We show that this slight difference is at least in part an environmental effect. The scatter of the cluster Tully-Fisher relation increases for galaxies closer to the core region, also indicating an environmental effect. Interestingly, dusty red galaxies become fainter towards the core at a given rotation velocity (i.e. total mass). This indicates that the star formation in these galaxies is in the process of being quenched. The luminosities of normal spiral galaxies are slightly higher at fixed rotation velocity for smaller cluster-centric radii. These galaxies are probably gas-rich (compared to the dusty red population) and the onset of ram-pressure stripping increases their star-formation rates. Galaxies with smooth morphology show higher root mean square values in the fitting of their rotation curves. This is particularly the case for dusty red galaxies. A cluster-specific interaction process like ram-pressure stripping is the best explanation, since it only affects the gaseous disc but not the stellar morphology. Conclusions. The results from the Tully-Fisher analysis are consistent with and complement our previous findings. Dusty red galaxies might be an intermediate stage in the transformation of infalling field spiral galaxies into cluster lenticulars (also known as S0s), and this might explain the well-known increase of the S0 fraction in galaxy clusters with cosmic time.
The implementation of the 2013 European Society of Cardiology (ESC) Core Curriculum guidelines for acute cardiovascular care (acc) training among European countries is unknown. We aimed to evaluate ...the current status of acc training among cardiology trainees and young cardiologists (<40 years) from ESC countries.
The survey (March-July 2019) asked about details of cardiology training, self-confidence in acc technical and non-technical skills, access to training opportunities, and needs for further training in the field. Overall 614 young doctors, 31 (26-43) years old, 55% males were surveyed. Place and duration of acc training differed between countries and between centres in the same country. Although the majority of the respondents (91%) had completed their acc training, the average self-confidence to perform invasive procedures and to manage acc clinical scenarios was low-44% (27.3-70.4). The opportunities for simulation-based learning were scarce-18% (5.8-51.3), as it was previous leadership training (32%) and knowledge about key teamwork principles was poor (48%). The need for further acc training was high-81% (61.9-94.3). Male gender, higher level of training centres, professional qualifications of respondents, longer duration of acc/intensive care training, debriefings, and previous leadership training as well as knowledge about teamwork were related to higher self-confidence in all investigated aspects.
The current cardiology training program is burdened by deficits in acc technical/non-technical skills, substantial variability in programs across ESC countries, and a clear gender-related disparity in outcomes. The forthcoming ESC Core Curriculum for General Cardiology is expected to address these deficiencies.
Organizations are increasingly aware that a better vocational inclusion of persons with disabilities (PWD) is in their self-interest for reasons such as a shortage of skilled labor, an increasing ...prevalence of disability in their aging workforces, and changed societal attitudes and laws regarding the promotion of diversity and equity in the workplace. Human resource (HR) practices have been identified as a primary enabler of inclusion, yet research on disability-related HR Management is scattered across disciplines. To provide an evidence-based analysis and integration, this article systematically reviews the literature on HR management in the context of employing persons with disabilities, using the high-performance work practices 'selection and staffing', 'training and development', '(performance) appraisal, promotion, and career management' and 'compensation and benefits' as an organizing framework. We systematically reviewed and summarized the key findings of 74 empirical studies conducted from 1990 through 2020. Most studies focused on selection and staffing practices, providing strong evidence that standardization and structure reduce bias in the appraisal of PWD and related employment decisions. Research regarding appropriate HR practices that allow to utilize, develop and reward PWDs' potential, in contrast, is still in its infancy.
Previous studies showed an association between apelin and atrial fibrillation (AF). The aim of this study was to analyse the effect of pulmonary vein isolation (PVI) in patients with paroxysmal AF on ...plasmatic apelin concentrations.
Nine consecutive patients (aged from 43 to 69 years, 3 females and 6 males) with documented paroxysmal atrial fibrillation and implanted loop recorders (ILR) for continuous ECG monitoring were included in this study. All the patients underwent a radiofrequency catheter ablation with PVI.
The plasmatic concentration of apelin increased after PVI. The average plasmatic concentration of apelin before PVI was 0.299 ng/ml (±0.16), 3 months after PVI 0.462 ng/ml (±0.10) and 9 months after PVI 0.565 ng/ml (±0.146). There was an increase in the concentration of apelin 3 months and 9 months after the PVI by 0.163 ng/ml (p=0.07) and by 0.266 ng/ml (p=0.01), respectively. The concentration of apelin inversely correlated with the AF burden (r=-0.44, p=0.03).
Our study showed a significant increase in apelin levels after the reduction of AF burden via PVI and an inverse correlation with AF burden. Apelin might be a promising marker of AF (Tab. 2, Fig. 2, Ref. 28).
Objectives:
Telemedicine was increasingly adopted in otolaryngology as a result of the COVID-19 pandemic, but how it compares to in-person visits over the longitudinal course of the pandemic has not ...been characterized. This study compares telemedicine visits to in-person visits on measures of clinical efficiency and patient satisfaction.
Methods:
We examined all in-person and telemedicine encounters that occurred during the 13-month period from April 1, 2020 to April 30, 2021 at a pediatric otolaryngology clinic associated with a large tertiary care children’s hospital. We compared patient demographics, primary encounter diagnoses, completions, cancellations, no-shows, cycle time, and patient satisfaction.
Results:
A total of 19 541 (90.5%) in-person visits and 2051 (9.5%) telemedicine visits were scheduled over the study period. There was no difference in patient age or gender between the visit types. There was a difference in race (75% White or Caucasian for in-person and 73% for telemedicine, P = .007) and average travel distance (53.3 miles for in-person vs 71.0 for telemedicine, P = .000). The most common primary diagnosis was Eustachian tube dysfunction for in-person visits (11.8%) and sleep disordered breathing for telemedicine visits (13.7%). Completion rate was greater for telemedicine visits (52.4% in-person vs 62.5% telemedicine). Cancellations were greater for in-person visits (42.6% in-person vs 24.2% telemedicine), but no-shows were greater for telemedicine (5.0% in-person vs 13.3% telemedicine, all P = .000). Average cycle time was shorter for telemedicine visits (56.5 minutes in-person vs 47.6 minutes telemedicine, P = .000). Patient satisfaction with provider interactions and overall care experience was high for both visit types.
Conclusions:
Telemedicine was utilized more during months of heightened COVID-19 cases, with higher completion rates, fewer cancellations, shorter cycle times, saved travel distance, and comparable patient satisfaction to in-person visits. Telemedicine has the potential to remain an efficient mode of care delivery in the post-pandemic era.
Senior medical students are facing an unparalleled experiential gap left by COVID-19 restrictions. Due to a shared commitment to safety, equity, and well-being, away rotations are actively being ...discouraged or even prohibited. As a result, students transitioning to residency encounter reduced clinical training experiences and decreased access to advising, mentorship, and research opportunities. In addition, limited exposure to residency life across subspecialties and institutions poses unique challenges during the current residency application cycle. The otolaryngology-head and neck surgery community has met these unprecedented challenges by producing diverse electronic resources for specialty-specific clinical education, as well as discussing ways to increase access to advising. In this commentary, we review these initiatives and propose an institutional virtual event as a platform for meeting goals previously achieved by visiting subinternships.
The states (Schrödinger picture) and observables (Heisenberg picture) in the standard quantum theory evolve symmetrically in time, given by the unitary group with time extending over − < t < + . This ...time evolution is a mathematical consequence of the Hilbert space boundary condition for the dynamical differential equations. However, this unitary group evolution violates causality. Moreover, it does not solve an old puzzle of Wigner: How does one describe excited states of atoms which decay exponentially, and how is their lifetime τ related to the Lorentzian width Γ? These question can be answered if one replaces the Hilbert space boundary condition by new, Hardy space boundary conditions. These Hardy space boundary conditions allow for a distinction between states (prepared by a preparation apparatus) and observables (detected by a registration apparatus). The new Hardy space quantum theory is time asymmetric, i.e, the time evolution is given by the semigroup with t0 ≤ t < + , which predicts a finite "beginning of time" t0, where t0 is the ensemble of time at which each individual system has been prepared. The Hardy space axiom also leads to the new prediction: the width Γ and the lifetime τ are exactly related by τ ℏ/Γ.
Nucleosomes are a significant barrier to the repair of UV damage because they impede damage recognition by nucleotide excision repair (NER). The RSC and SWI/SNF chromatin remodelers function in cells ...to promote DNA access by moving or evicting nucleosomes, and both have been linked to NER in yeast. Here, we report genome-wide repair maps of UV-induced cyclobutane pyrimidine dimers (CPDs) in yeast cells lacking RSC or SWI/SNF activity. Our data indicate that SWI/SNF is not generally required for NER but instead promotes repair of CPD lesions at specific yeast genes. In contrast, mutation or depletion of RSC subunits causes a general defect in NER across the yeast genome. Our data indicate that RSC is required for repair not only in nucleosomal DNA but also in neighboring linker DNA and nucleosome-free regions (NFRs). Although depletion of the RSC catalytic subunit also affects base excision repair (BER) of
-methylpurine (NMP) lesions, RSC activity is less important for BER in linker DNA and NFRs. Furthermore, our data indicate that RSC plays a direct role in transcription-coupled NER (TC-NER) of transcribed DNA. These findings help to define the specific genomic and chromatin contexts in which each chromatin remodeler functions in DNA repair, and indicate that RSC plays a unique function in facilitating repair by both NER subpathways.
Objective:
The COVID-19 pandemic has introduced a period of social isolation that has challenged the ability of providers to uphold in-person patient care. Although commonplace in pediatric ...otolaryngology, multidisciplinary clinics pose a unique challenge during this time due to increased infection risk from multiple patient-provider interactions. Guidance on the application of telemedicine for multidisciplinary clinics in pediatric otolaryngology is limited.
Methods:
We provide comprehensive guidance on best practices for conducting telemedicine visits for a number of multidisciplinary otolaryngology clinics using our experiences at a single tertiary care children’s hospital. A review of literature to support the adoption of telemedicine in multidisciplinary pediatric otolaryngology is also incorporated.
Results:
Telemedicine was successfully adopted for 7 multidisciplinary pediatric clinics with a variety of specialists: aerodigestive disorders, congenital hearing loss, microtia/aural atresia, orofacial clefting, sleep disorders, tracheostomy care, and velopharyngeal dysfunction.
Conclusions:
Telemedicine is feasible for a variety of multidisciplinary clinics and its optimization is critical for providing care to complex pediatric otolaryngology patients during the COVID-19 pandemic and beyond.
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