Abundant zircon grains were found within a metasomatic chlorite–corrensite (trioctahedral regularly interstratified chlorite/smectite) shell that surrounds rodingite from the Jordanów–Gogołów (JG) ...serpentinite massif (Sudetic ophiolite, Bohemian Massif). The zircon grains bear two types of primary fluid inclusions containing either liquid CO
2 or aqueous solutions. The inclusions were used to assign the
P–
T conditions of the zircon formation (270–300 °C, ca. 1 kbar), using the crossed-isochore method. Abraded single zircon grains give a U–Pb age of 400+4/−3 Ma, which is interpreted as the age of zircon crystallization. This zircon formed during rodingitization, i.e., a metasomatic process directly connected with the serpentinization and thus provides the opportunity of direct dating of the early serpentinization process.
The zircon age from the Jordanów–Gogołów massif is consistent with the crystallization age of metagabbro protoliths from the Sudetic ophiolite as determined by Oliver et al. J. Geol. Soc. (Lond.) 150 (1993) 355. A Ce anomaly, combined with the mineralogical record of greenschist facies metamorphism of the mafic rocks from Sudetic ophiolite, suggests that the Sm–Nd whole-rock isotopic data of Pin et al. Lithos 21 (1988) 195 (353±21 Ma) possibly characterize the age of later metamorphic event.
Poa
annua
, an alien species reported from the Antarctic continent and many Antarctic and sub-Antarctic islands, was accidentally introduced in the vicinity of the Polish Antarctic Station H. ...Arctowski. Recently the species has been found entering native plant communities. In almost 30 years it dispersed over 250 m from the site it was first observed and can therefore be considered invasive. We report the first steps to eradicate the species following the initial research to quantify the biology, ecology and genetics of the species. After detailed mapping of all 1439 tussocks located in the Arctowski Station area we removed 314 tussocks closest to a moss carpet formation (native plant community of high conservation value). All of the 49 tussocks growing in the Ecology Glacier forefield were removed. It is the biggest alien plant eradication act conducted so far in Antarctica. We plan to continue the eradication process and monitor the eradicated sites. This will provide valuable information on impacts and issues related to removal of alien species in the maritime Antarctic and will help in informing future decisions on management of other plant invasions in the region. Given the increasing human traffic to the Antarctic and the associated risks of invasion our results will be important not only for Arctowski but also for the whole Antarctic region.
The aim of the study was to evaluate pelvic floor muscle bioelectrical activity in healthy, young, and nulliparous women, and to present normative values for all phases and parameters measured with ...the Glazer Protocol.In this study, 96 healthy, young, nulliparous women (age 22-27 years; 168.6 ± 5.1 cm; 57.1 ± 11.8 kg) were tested. The bioelectrical activity of the pelvic floor muscles was collected using an endovaginal electrode with the Glazer Protocol, which included the following series of muscles contractions and relaxations: pre-baseline rest, phasic contractions, tonic contractions, isometric contractions for muscle endurance evaluation, and post-baseline rest.The following normative values of the bioelectrical signal for all phases of the Glazer Protocol were calculated: mean, minimal, and maximal values, 95% confidence interval, standard deviation, 95% standard deviation confidence interval, variance, coefficient of variation, and standard error of measurement. Average Mean Amplitude (μV) was as follows: pre-baseline rest (6.26 ± 3.33 μV), phasic contractions (49.76 ± 26.44 μV), tonic contractions (37.05 ± 25.99 μV), endurance contraction (16.10 ± 6.68 μV), and post-baseline rest (6.93 ± 3.99 μV).This study was the first in which normative values for all phases of the Glazer Protocol were reported. This protocol is very often used in electromyography devices as a tool for pelvic floor muscle assessment. Due to the fact that the interpretation of the pelvic floor muscle evaluation is complex and difficult, the authors believe that the normative values proposed in this study allow for comprehensive interpretation of this test (both qualitatively and quantitatively) and provide a reference point for parameters measured in women with different pelvic floor dysfunctions.
An evaluation of the genetic conditioning of evoking pain Pacian, Anna; Kocki, Janusz; Pacian, Jolanta ...
AAEM. Annals of Agricultural and Environmental Medicine/Annals of Agricultural and Environmental Medicine,
01/2020, Letnik:
27, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Introduction and objective: Pain is an integral element of the pathogenic process and sometimes determines its course. Disorders in pain sensation, as well as its lack, the pain threshold, and ...variability in sensation of the same pain stimuli as more or less intensive by different persons, may be genetically conditioned. The aim of the study is to examine genes in pathogenesis of chronic pain. Material and methods: The study was conducted in a specially selected group of 31 persons: study group – 20 patients with chronic pain, and control group – 11 healthy individuals who did not experience pain. The control group of 11 healthy persons, compared with the study group, was the catalyst for determining the relative quantification (RQ) of gene expression. Biological material in the form of venous blood was collected from the study participants into the tubes containing anticoagulant EDTA KE/2.7 ml (ethylenediaminetetraacetic acid), preventing extracorporeal blood clotting. Results: Analysis of expression of the examined genes showed over-expression of the DRD1 gene in patients experiencing chronic pain, which means that in these patients an increased number of dopamine D1 receptors encoded by this gene should be expected. The dopamine D1 receptor is a G-protein-coupled receptor which regulates (stimulates or inhibits) adenyl cyclase – the enzyme responsible for synthesis of cyclic AMP (cAMP). An increase in the concentration of cAMP in neurons enhances the sensation of pain. Conclusions: The genes (DRD1, COMT, OPRK1, HCN2) have a significant role in the pathogenesis of chronic pain in various diseases; they can also influence the perception of pain. Knowledge of these genes can contribute to the development of effective methods of combating pain.
High-density lipoprotein (HDL) remodeling within the plasma compartment and the association between lecithin-cholesterol acyltransferase (LCAT) and cholesterol ester transfer protein (CETP) activity, ...and lipid, lipoprotein concentrations and composition were investigated. The aim was to examine the high sensitivity of C-reactive protein (hsCRP), lipid, apolipoprotein B (apoB), apoAI, total apoAII, apoAIInonB, apoB-containing apoAII (apoB:AII), total apoCIII, apoCIIInonB, apoB-containing apoCIII (apoB:CIII) concentration and LCAT and CETP activity to gain an insight into the association between them and LCAT and CETP, 57 post-renal transplant (Tx) patients with and without statin therapy and in 15 healthy subjects. Tx patients had moderate hypertriglyceridemia, hypercholesterolemia, and dyslipoproteinemia, disturbed triglyceride-rich lipoproteins (TRLs) and HDL composition, decreased LCAT, and slightly increased hsCRP but no CETP activity. Spearman’s correlation test showed the association between lipids and lipoproteins and LCAT or CETP, and multiple ridge stepwise forward regression showed that immunosuppressive therapy in Tx patients can disturb HDL and TRLs composition. The results suggest that inhibition or activation of LCAT is due, in part, to HDL-associated lipoprotein. Lipoprotein composition of apoAI, apoAIInonB, and apoCIIInonB in HDL particle and apoB:AII TRLs can contribute to decrease LCAT mass in Tx patients. Tx patients without statin and with lower triglycerides but higher HDL cholesterol concentration and disturbed lipoprotein composition of ApoAI and apoAII in HDL particle can decrease LCAT, increase LDL cholesterol, aggravate renal graft, and accelerate atherosclerosis and chronic heart diseases.
An increased loss of bone density during the first years after menopause induces osteoporosis.
The aim of the research presented in this paper was to ascertain the difference in the rate of ...involutional changes in bone tissue in former athletes and in non-athletes of the same age.
The research involved 18 former swimmers and 18 females of similar age who had never practiced sports. The subjects were subdivided into two subgroups: Subgroup I had been post-menopausal for < or = 5 years, and Subgroup II for > 5 years; this was done to assess bone mineral content relative to the length of the postmenopausal time period. Bone mineral content (BMC) and bone mineral density (BMD) were measured in lumbar vertebrae by dual-emission X-ray absorptiometry (DXA). Bone strength was measured in the heel using the bone stiffness index. Each subject was examined twice, with a one-year period in between. A diagnostic questionnaire was used to compile date on the subjects' physical activity and their gonad functioning. Dietary habits (calcium intake) were established by three interviews and the Dieta 4.0 computer program. Results. Anthropometric features did not differentiate the subjects in the subgroups. Former athletes in both subgroups spent off-work time on physical activities significantly more frequently. In both groups, calcium intake was sufficient and did not exceed 3/4 of the daily norm. A higher calcium intake was found in former athletes compared to non-athletes. The subjects in Subgroup I had significantly greater BMC and BMD than those in Subgroup II. In Subgroup I, the second examination showed somewhat lower reductions in BMC and BMD among the former athletes than among the non-athletes. In Subgroup II, BMC and BMD increased somewhat among the former athletes, while non-significant reductions were observed in the BMC and BMD of the non-athletes. All the subjects undertook pharmacologic treatment after the first examination, which caused improvement of bone parameters in the second examination.
The rate of bone mass loss in former athletes proved to be consistent with the involutional process and similar to that of non-athletes. The reduced BMD in the lumbar vertebrae of 22% of the women in the study demonstrates the need for regular densitometric examinations in postmenopausal females.
The high frequency of cases of circulatory system conditions in Europe and other countries around the world requires scientific research to define risk factors of early atherosclerotic changes. The ...aim of the present study was to define which students are at danger of developing atherosclerosis by means of measuring cholesterol and triglyceride levels in blood as well as defining the correlation between atherosclerosis risk factors and arterial blood pressure, physical fitness and efficiency of the subjects.
The research covered 167 students of Public Junior High School 1 in Biala Podlaska aged 13-15 years. Accutrend GCT was employed to define the levels of total cholesterol and triglycerides in the screen test. Those students who were found to have increased values of biochemical parameters of capillary blood were subjected to additional blood tests aiming to define complete lipid profile of venous blood. The blood pressure in subjects was tested three times. The Moderate-to-Vigorous Physical Activity (MVPA) test, suggested by American authors, was employed to define physical activity in subjects. EUROFIT was employed to define physical efficiency.
Among the 167 subjects there were found 42 students (25.1%) whose lipid level in capillary blood proved to be increased. Full lipid profile tests proved that 16 students (9.6%) had increased blood lipid levels; those subjects constituted the risk group. Subjects in the risk group were characterized by lower levels of physical activity and physical efficiency compared to subjects with normal blood lipid level. Moreover, the frequency of hypertension was greater in risk group subjects compared to subjects with normal blood lipid levels.
Students diagnosed with atherosclerosis risk factors require observation and early prophylactics by adopting habits of healthy physical activity.
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