El agua subterránea es la principal fuente de consumo en muchos centros urbanos y áreas rurales de Bolivia, tal es el caso del Municipio de San Pedro ubicado en el departamento de Santa Cruz. El ...presente estudio se realizó con la Received 04 12 2021 Accepted 04 26 2020 Published 04 30 2021 Vol. 38, No.1, pp. 46-55, Ene./Abr.2021 Revista Boliviana de Química 38(1), 46-55, Jan./Apr. 2021 Bolivian Journal of Chemistry DOI: 10.34098/2078-3949.38.1.5 REVISTA BOLIVIANA DE QUÍMICA ISSN 0250-5460 Rev. Bol. Quim. Paper edition ISSN 2078-3949 Rev. boliv. quim. Electronic edition Lizangela Huallpara L. et al. RBQ Vol.38, No.1, pp. 46-55, 2021 Downloadable from: Revista Boliviana de Química. Volumen 38 Nº1. Año 2021 http://www.bolivianchemistryjournal.org, http://www.scribd.com/bolivianjournalofchemistry 47 Received 04 12 2021 38(1); Jan./Apr. 2021 Accepted 04 26 2021 Published 04 30 2021; DOI:10.34098/2078-3949.38.1.5 finalidad de determinar la calidad fisicoquímica del agua subterránea de consumo en 16 comunidades rurales ubicadas dentro del municipio de San Pedro. Los resultados mostraron valores de pH ligeramente alcalinos comprendidos entre 7,8 y 8,6 y la conductividad eléctrica mostró valores en un rango que va de 313,3 a 1189 µS/cm. Las aguas son predominantemente del tipo Na-HCO3 y contienen elevadas concentraciones de fluoruro (F- ) en un rango que va de 2,1 a 6,4 mg/L excediendo el valor máximo recomendado por la Organización Mundial para la Salud (OMS). Cálculos de índice de saturación (IS) muestran que la fase mineral que podría dar origen al elevado contenido de F- en agua es la F-Apatita.
No defects related to deficiency of the Wiskott-Aldrich Syndrome protein (WASp) have been described in osteoclasts. Here we show that there are significant morphologic and functional abnormalities. ...WASp-null cells spread over a much larger surface area and are highly polykaryotic. In their migratory phase, normal cells assemble clusters of podosomes behind their leading edges, whereas during the bone resorptive phase multiple podosomes are densely aggregated in well-defined actin rings forming the sealing zone. In comparison, WASp-null osteoclasts in either phase are markedly depleted of podosomes. On bone surfaces, this results in a failure to form actin rings at sealing zones. Complementation of WASp-null osteoclasts with an enhanced green fluorescent protein (eGFP)-WASp fusion protein restores normal cytoarchitecture. These structural disturbances translate into abnormal patterns of bone resorption both in vitro on bone slices and in vivo. Although physiologic steady-state levels of bone resorption are maintained, a major impairment is observed when WASp-null animals are exposed to a resorptive challenge. Our results provide clear evidence that WASp is a critical component of podosomes in osteoclasts and indicate a nonredundant role for WASp in the dynamic organization of these actin structures during bone resorption. (Blood. 2004;103:3552-3561)
Antifouling activity of green-synthesized 7-hydroxy-4-methylcoumarin Prez, Miriam; Mnica GarcaauthorCentro de Investigacin y Desarrollo en Tecnologa de Pinturas (CIDEPINT), Calle 52 e/ 121 y 122, 1900 La Plata, Argentina; Diego RuizauthorCentro de Investigacin en Sanidad Vegetal (CISaV), Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, Calle 60 y 119, 1900 La Plata, Argentina ...
2015
Journal Article
Postharvest senescence of florets from primary and secondary broccoli inflorescences Hasperu, Joaqun H; Laura LemoineauthorCentro de Investigacin y Desarrollo en Criotecnologa de Alimentos (CIDCA)-CONICET, calle 47 y 116, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP), 47 y 115, 1900, La Plata, ArgentinaLaboratorio de Investigacin en Productos Agroindustriales (LIPA), Facultad de Ciencias Agrarias y Forestales- UNLP, calle 60 y 119, CP 1900, La Plata, Argentina; Ariel R. VicenteauthorCentro de Investigacin y Desarrollo en Criotecnologa de Alimentos (CIDCA)-CONICET, calle 47 y 116, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP), 47 y 115, 1900, La Plata, ArgentinaLaboratorio de Investigacin en Productos Agroindustriales (LIPA), Facultad de Ciencias Agrarias y Forestales- UNLP, calle 60 y 119, CP 1900, La Plata, Argentina ...
2015
Journal Article
Podosomes are actin-based adhesions involved in migration of cells that have to cross tissue boundaries such as myeloid cells. The Wiskott Aldrich Syndrome Protein regulates de novo actin ...polymerization during podosome formation and it is cleaved by the protease calpain during podosome disassembly. The mechanisms that may induce the Wiskott Aldrich Syndrome Protein cleavage by calpain remain undetermined. We now report that in myeloid cells, tyrosine phosphorylation of the Wiskott Aldrich Syndrome Protein-tyrosine291 (Human)/tyrosine293 (mouse) not only enhances Wiskott Aldrich Syndrome Protein-mediated actin polymerization but also promotes its calpain-dependent degradation during podosome disassembly. We also show that activation of the Wiskott Aldrich Syndrome Protein leading to podosome formation occurs independently of tyrosine phosphorylation in spleen-derived dendritic cells. We conclude that tyrosine phosphorylation of the Wiskott Aldrich Syndrome Protein integrates dynamics of actin and cell adhesion proteins during podosome disassembly required for mobilization of myeloid cells during the immune response.
The role of lactate on the immunomodulatory properties of the nonbacterial fraction of kefir Iraporda, Carolina; David E. RomaninauthorLaboratorio de Investigaciones del Sistema Inmune (LISIN, UNLP), Calle 47 y 115, 1900 La Plata, Argentina; Martn RumboauthorLaboratorio de Investigaciones del Sistema Inmune (LISIN, UNLP), Calle 47 y 115, 1900 La Plata, Argentina ...
2015
Journal Article
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