Neutrinos emitted deep within a supernova explosion experience a self-induced index of refraction. In the stationary, one-dimensional (1D) supernova "bulb model," this self-induced refraction can ...lead to a collective flavor transformation which is coherent among different neutrino momentum modes. Such collective oscillations can produce partial swaps of the energy spectra of different neutrino species as the neutrinos stream away from the proto-neutron star. However, it has been demonstrated that the spatial symmetries (such as the spherical symmetry in the bulb model) can be broken spontaneously by collective neutrino oscillations in multidimensional models. Using a stationary, 2D neutrino ring model we demonstrate that there exist two limiting scenarios where collective oscillations may occur. In one limit, the collective flavor transformation begins at a radius with relatively high neutrino densities and develops small-scale flavor structures. The loss of the spatial correlation in the neutrino flavor field results in similar (average) energy spectra for the antineutrinos of almost all energies and the neutrinos of relatively high energies. In the other limit, the flavor transformation starts at a radius where the neutrino densities are smaller (e.g., due to the suppression of the high matter density near the proto-neutron star). Although the spatial symmetry is broken initially, it is restored as the neutrino densities decrease, and the neutrinos of different flavors partially swap their energy spectra as in the 1D bulb model. This finding may have interesting ramifications in other aspects of supernova physics.
To conduct a systematic review and meta-analysis quantifying the effects of isometric resistance training on the change in systolic blood pressure(SBP), diastolic blood pressure (DBP), and mean ...arterial pressure in subclinical populations and to examine whether the magnitude of change in SBP and DBP was different with respect to blood pressure classification.
We conducted a systematic review and meta-analysis of randomized controlled trials lasting 4 or more weeks that investigated the effects of isometric exercise on blood pressure in healthy adults (aged ≥18 years) and were published in a peer-reviewed journal. PubMed, CINAHL, and the Cochrane Central Register of Controlled Trials were searched for trials reported between January 1, 1966, and July 31, 2013. We included 9 randomized trials, 6 of which studied normotensive participants and 3 that studied hypertensive patients, that included a total of 223 participants (127 who underwent exercise training and 96 controls).
The following reductions were observed after isometric exercise training: SBP-mean difference (MD), -6.77 mm Hg (95% CI, -7.93 to -5.62 mm Hg; P<.001); DBP-MD, -3.96 mm Hg (95% CI, -4.80 to -3.12 mm Hg; P<.001); and mean arterial pressure-MD, -3.94 mm Hg (95% CI, -4.73 to -3.16 mm Hg; P<.001). A slight reduction in resting heart rate was also observed (MD, -0.79 beats/min; 95% CI, -1.23 to -0.36 beats/min; P=.003).
Isometric resistance training lowers SBP, DBP, and mean arterial pressure. The magnitude of effect is larger than that previously reported in dynamic aerobic or resistance training. Our data suggest that this form of training has the potential to produce significant and clinically meaningful blood pressure reductions and could serve as an adjunctive exercise modality.
Weather may marginally affect COVID-19 dynamics, but misconceptions about the way that climate and weather drive exposure and transmission have adversely shaped risk perceptions for both policymakers ...and citizens. Future scientific work on this politically-fraught topic needs a more careful approach.
The biological effectiveness of proton beams relative to photon beams in radiation therapy has been taken to be 1.1 throughout the history of proton therapy. While potentially appropriate as an ...average value, actual relative biological effectiveness (RBE) values may differ. This Task Group report outlines the basic concepts of RBE as well as the biophysical interpretation and mathematical concepts. The current knowledge on RBE variations is reviewed and discussed in the context of the current clinical use of RBE and the clinical relevance of RBE variations (with respect to physical as well as biological parameters).
The following task group aims were designed to guide the current clinical practice:
Assess whether the current clinical practice of using a constant RBE for protons should be revised or maintained.
Identifying sites and treatment strategies where variable RBE might be utilized for a clinical benefit.
Assess the potential clinical consequences of delivering biologically weighted proton doses based on variable RBE and/or LET models implemented in treatment planning systems.
Recommend experiments needed to improve our current understanding of the relationships among in vitro, in vivo, and clinical RBE, and the research required to develop models. Develop recommendations to minimize the effects of uncertainties associated with proton RBE for well‐defined tumor types and critical structures.
We present quantum Monte Carlo calculations of light nuclei, neutron-α scattering, and neutron matter using local two- and three-nucleon (3N) interactions derived from chiral effective field theory ...up to next-to-next-to-leading order (N(2)LO). The two undetermined 3N low-energy couplings are fit to the (4)He binding energy and, for the first time, to the spin-orbit splitting in the neutron-α P-wave phase shifts. Furthermore, we investigate different choices of local 3N-operator structures and find that chiral interactions at N(2)LO are able to simultaneously reproduce the properties of A=3,4,5 systems and of neutron matter, in contrast to commonly used phenomenological 3N interactions.
Quantum Monte Carlo techniques aim at providing a description of complex quantum systems such as nuclei and nucleonic matter from first principles, i.e., realistic nuclear interactions and currents. ...The methods are similar to those used for many-electron systems in quantum chemistry and condensed matter physics, but are extended to include spin-isospin, tensor, spin-orbit, and three-body interactions. This review shows how to build the atomic nucleus from the ground up. Examples include the structure of light nuclei, electroweak response of nuclei relevant in electron and neutrino scattering, and the properties of dense nucleonic matter. Quantum Monte Carlo methods have proved valuable to study the structure and reactions of light nuclei and nucleonic matter starting from realistic nuclear interactions and currents. These ab initio calculations reproduce many low-lying states, moments, and transitions in light nuclei, and simultaneously predict many properties of light nuclei and neutron matter over a rather wide range of energy and momenta. The nuclear interactions and currents are reviewed along with a description of the continuum quantum Monte Carlo methods used in nuclear physics. These methods are similar to those used in condensed matter and electronic structure but naturally include spin-isospin, tensor, spin-orbit, and three-body interactions. A variety of results are presented, including the low-lying spectra of light nuclei, nuclear form factors, and transition matrix elements. Low-energy scattering techniques, studies of the electroweak response of nuclei relevant in electron and neutrino scattering, and the properties of dense nucleonic matter as found in neutron stars are also described. A coherent picture of nuclear structure and dynamics emerges based upon rather simple but realistic interactions and currents.
Although an extensive literature has shown that family structure is linked with child well-being, less well understood is how the dynamics within families affect children, in particular the extent to ...which positive mother—father relationship quality is linked with children's outcomes. In this study the authors used data from the Fragile Families and Child Wellbeing Study (N = 773) to examine how couple supportiveness in stable coresident families is related to children's externalizing and internalizing behavioral problems over ages 3 through 9. Using latent growth curve and fixed effects models, they found that parents' greater supportiveness has a slight association with lower levels of children's behavioral problems. Using cross-lagged structural equation models to examine the direction of the association, they also found some evidence that parents' relationship quality and children's behavioral problems are reciprocally related. Overall, this study suggests that more positive couple interactions are beneficial for children residing with both of their biological parents.
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