Objective:
To observe the efficacy of a plant-derived wound dressing (1 Primary Wound Dressing®), a mixture of hypericum and neem oil, in different types of paediatric burns.
Method:
A retrospective ...review was conducted over the complete healing course of 9 paediatric patients with a mean age of 8.17±3.35 (1–11 years), presenting mixed, partial or full-thickness burns. The treatment applied by the wound care specialist consisted of daily cleansing of the wound with a saline solution and application of 1 Primary Wound Dressing on the whole wound surface. There was no application of a secondary dressing. The time to heal, wound size, ease of handling, pain and complications were recorded. Procedural and background pain were observed in six of the patients older than 5 years (mean age 9.6±2.39, range 8–11 years). Due to the small number of patients examined during the period studied, it was not possible to perform statistical analyses.
Results:
The mean wound size was 50.76±48.32cm2 (4.63–132.0cm2). A rapid induction of granulation tissue and re-epithelialisation was observed. Time to complete healing was 16.6±4.69 days (10–22 days). No complications related to wound infection was observed. The 6 patients older than five years reported a strong relief of pain, from an initial value of 7–8 out of 10 to 0 out of 10 within the first week of treatment. This remained at the 0 out of 10 level during the second and third weeks of treatment.
Conclusion:
This retrospective, non-controlled examination suggests that 1 Primary Wound Dressing could be an effective therapy for the treatment of burn wounds, with benefits including pain reduction and simplicity of use. Further evaluations with a larger population are required to document the effectiveness of this plant-derived wound dressing in a controlled fashion.
Declaration of interest:
There were no external sources of funding for this study. F. Carnevali is a researcher and co-inventor of 1 Primary Wound Dressing®.
The loggerhead Caretta caretta is the most common sea turtle in the Mediterranean. Currently, sea turtles are considered endangered, mainly due to the impact of human activities. Among traumatic ...lesions, those involving the skull, if complicated by brain exposure, are often life-threatening. In these cases, death could be the outcome of direct trauma of the cerebral tissue or of secondary meningoencephalitis. This uncontrolled study aims to evaluate the use of a plant-derived dressing (1 Primary Wound Dressing®) in 3 sea turtles with severe lesions of the skull exposing the brain. Following surgical curettage, the treatment protocol involved exclusive use of the plant-derived dressing applied on the wound surface as the primary dressing, daily for the first month and then every other day until the end of treatment. The wound and peri-wound skin were covered with a simple secondary dressing without any active compound (non-woven gauze with petroleum jelly). Data presented herein show an excellent healing process in all 3 cases and no side effects due to contact of the medication with the cerebral tissue.
Epitypes are designated for the Mexican species Hechtia schottii and Hechtia stenopetala. Complete descriptions of the two taxa are presented as well as specimen citations and iconography depicting ...relevant characteristics of the species and plants in habitat. The first species, known only from the States of Campeche and Yucatán, was based upon pistillate material (old fruits and immature pistillate buds) and leaf fragments; the epitype adds the staminate flowers and complete leaves. The second species, restricted to the Veracruz State, was based upon a plant with old, open fruits; the epitype adds the staminate flowers and leaves.
St. John's wort is a medicinal plant with a long history of use in traditional medicine all over Europe. Traditional preparations and in particular the infused oil from SJW flowers remains one of the ...most popular and curative topical remedy against ulcerations and burns. The presence of the characteristic polyprenylated acylphloroglucinol derivatives, namely hyperforin and analogs are instead related to the oil's therapeutic activity. Indeed, it is well known that hyperforin has a potent antibacterial activity.
In this study we tried to rationalize the production system of the oily preparation in order to obtain the highest concentration and stability of phloroglucinols. Five different samples of SJW oils were evaluated by HPLC-DAD-MS analysis to verify the variability and stability of the constituents according to the following factors: different harvesting time, fresh or dried plant material, use of sunlight or heating systems during extraction. The stability of these oils during 1 year was also tested.
A new species of Crossoglossa (Orchidaceae: Epidendroideae: Malaxideae), Crossoglossa acuminatissima, from Santander del Sur Department in Colombia, is described and illustrated, and its affinities ...are discussed. Malaxis tipuloides var. exigua is raised to the rank of species as Crossoglossa exigua, and its report from Venezuela constitutes the first record of the genus Crossoglossa in that country. /// Se describe Crossoglossa acuminatissima de Santander del Sur en Colombia y se provee una ilustración y una discusión de sus afinidades. Malaxis tipuloides var. exigua se eleva al rango de especie como Crossoglossa exigua, y su reporte para Venezuela constituye el primer registro del género en ese país.
A new species of Malaxis Solander ex Swartz (Orchidaceae, Epidendroideae, Malaxideae), M. medinae Carnevali & Noguera Savelli, from Trujillo State in Andean Venezuela is proposed herein. The new ...taxon is related to the widespread M. soulei L. O. Williams, a species found from the southwestern United States southward into Panama. The plants, however, are smaller (to only 12.7 cm) and have proportionally longer peduncles (to 4.5 cm) that bear fewer flowers (12 to 25 per spike) with a much more triangular labellum with parallel apical teeth (vs. convergent in M. soulei).
Tillandsia tehuacana I. Ramírez & Carnevali, a new species in the T. utriculata (L.) L. complex (Bromeliaceae) from Puebla, Mexico, is described and illustrated. The new entity is similar to T. ...makoyana Baker, but the rosettes are cylindrical (vs. funnelform), the leaves are coriaceous (vs. sclerotic), the leaves have a proportionately larger sheath compared with the lamina (vs. leaves with the sheath and lamina subequal), and the rachis of the inflorescence is sharply flexuous (vs. straight). The new species is also characterized by its habit, since it usually grows in dry thorn-scrub-cactus associations, while T. makoyana grows in different vegetation types, including oak and low deciduous forests. The new entity is also similar to T. pinicola I. Ramírez & Carnevali, but the new taxon differs by its larger rosette and inflorescence, its tubular rosette with leaves that are gray and purple and white lepidote on both sides (vs. a funnelform rosette with green leaves and only sparsely white lepidote abaxially), the floral bracts much shorter than the sepals (vs. subequal), the flowers ovate in shape (vs. tubular), and the three stigmatic lobes twisted together (vs. not twisted together).
Two new species in the Tillandsia utriculata (L.) L. complex (Bromeliaceae) from Mexico are proposed. Both are herein described and illustrated with their affinities discussed. The first new entity, ...T. aesii I. Ramírez & Carnevali from the states of Jalisco, Guerrero, and Oaxaca, is similar to T. makoyana Baker, but the new taxon has an open rosette with leaves that are green adaxially and white lepidote abaxially (vs. a funnelform rosette with gray leaves on both surfaces in T. makoyana), actinomorphic flowers with a light apple-green corolla (vs. zygomorphic with a purple to light purple corolla). The second taxon proposed here, T. pinicola I. Ramírez & Carnevali, from the state of Oaxaca, is also similar to T. makoyana, but is a smaller plant with a more compact growth habit and leaves with proportionally shorter leaf blades that abruptly attenuate from a broad sheath (vs. gradually attenuate into the proportionally longer blade) into a sub-acicular apex. It is also characterized by typically growing on pines, hence the epithet.
The existence of cooperation and trust between competing economic agents is taken for granted by much of the literature on industrial districts. This article explores the structure of the Birmingham ...jewellery-making district and the problems created by the opportunistic behaviour of many of its members. Archival sources show that the district was plagued by endemic dishonesty and that proximity did not generate trust and cooperation. The absence of barriers to entry into the trade created a district where social sanctions could not be used to reduce moral hazard. All these factors threatened to destroy the district during the crisis of the 1880s. The article shows how firms joined together to create the Birmingham Jewellers Association, to establish and enforce 'rules of the game', with the aim of reducing transaction costs.
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