Abstract
We search for passive galaxies at z > 3 in the GOODS-South field, using different techniques based on photometric data, and paying attention to develop methods that are sensitive to objects ...that have become passive shortly before the epoch of observation. We use CANDELS HST catalogues, ultra-deep Ks data and new IRAC photometry, performing spectral energy distribution fitting using models with abruptly quenched star formation histories. We then single out galaxies which are best fitted by a passively evolving model, and having only low probability (<5 per cent) star-forming solutions. We verify the effects of including nebular lines emission, and we consider possible solutions at different redshifts. The number of selected sources dramatically depends on the models used in the spectral energy distribution (SED) fitting. Without including emission lines and with photometric redshifts fixed at the CANDELS estimate, we single out 30 candidates; the inclusion of nebular lines emission reduces the sample to 10 objects; allowing for solutions at different redshifts, only two galaxies survive as robust candidates. Most of the candidates are not far-infrared emitters, corroborating their association with passive galaxies. Our results translate into an upper limit in the number density of ∼0.173 arcmin2 above the detection limit. However, we conclude that the selection of passive galaxies at z > 3 is still subject to significant uncertainties, being sensitive to assumptions in the SED modelling adopted and to the relatively low S/N of the objects. By means of dedicated simulations, we show that JWST will greatly enhance the accuracy, allowing for a much more robust classification.
Context. Establishing the number of faint active galactic nuclei (AGNs) at z = 4−6 is crucial to understanding their cosmological importance as main contributors to the reionization of the Universe. ...Aims. In order to derive the AGN contribution to the cosmological ionizing emissivity we have selected faint AGN candidates at z> 4 in the CANDELS GOODS-South field, which is one of the deepest fields with extensive multiwavelength coverage from Chandra, HST, Spitzer, and various ground-based telescopes. Methods. We have adopted a relatively novel criterion. As a first step, high redshift galaxies are selected in the NIR H band down to very faint levels (H ≤ 27) using reliable photometric redshifts. At z> 4 this corresponds to a selection criterion based on the galaxy rest-frame UV flux. AGN candidates are then picked up from this parent sample if they show X-ray fluxes above a threshold of FX ∼ 1.5 × 10-17 erg cm-2 s-1 (0.5−2 keV), corresponding to a probability of spurious detections of 2 × 10-4 in the deep X-ray 4 Ms Chandra image. Results. We have found 22 AGN candidates at z> 4 and we have derived the first estimate of the UV luminosity function in the redshift interval 4 <z< 6.5 and absolute magnitude interval − 22.5 ≲ M1450 ≲ −18.5 typical of local Seyfert galaxies. The faint end of the derived luminosity function is about two to four magnitudes fainter at z ∼ 4−6 than that derived from previous UV surveys. We estimated ionizing emissivities and hydrogen photoionization rates in the same redshift interval under reasonable assumptions and after discussion of possible caveats, the most important being the large uncertainties involved in the estimate of photometric redshift for sources with featureless, almost power-law SEDs and/or low average escape fraction of ionizing photons from the AGN host galaxies. Both effects could, in principle, significantly reduce the estimated average volume densities and/or ionizing emissivities, especially at the highest redshifts. Conclusions. At z = 4−6.5 we argue that, under reasonable evaluations of possible biases, the probed AGN population can produce photoionization rates consistent with that required to keep the intergalactic medium observed in the Lyman-α forest of high redshift QSO spectra highly ionized, providing an important contribution to the cosmic reionization.
Abstract
We study the spectrophotometric properties of a highly magnified (
) pair of stellar systems identified at
z
= 3.2222 behind the Hubble Frontier Field galaxy cluster MACS J0416. Five ...multiple images (out of six) have been spectroscopically confirmed by means of VLT/MUSE and VLT/X-Shooter observations. Each image includes two faint (
), young (
Myr), low-mass (
), low-metallicity (12 + Log(O/H) ≃ 7.7, or 1/10 solar), and compact (30 pc effective radius) stellar systems separated by
pc after correcting for lensing amplification. We measured several rest-frame ultraviolet and optical narrow (
km s
−1
) high-ionization lines. These features may be the signature of very hot (
K) stars within dense stellar clusters, whose dynamical mass is likely dominated by the stellar component. Remarkably, the ultraviolet metal lines are not accompanied by Ly
α
emission (e.g., C
iv
/Ly
α
), despite the fact that the Ly
α
line flux is expected to be 150 times brighter (inferred from the H
β
flux). A spatially offset, strongly magnified (
) Ly
α
emission with a spatial extent
kpc
2
is instead identified 2 kpc away from the system. The origin of such a faint emission could be the result of fluorescent Ly
α
induced by a transverse leakage of ionizing radiation emerging from the stellar systems and/or may be associated with an underlying and barely detected object (with
de-lensed). This is the first confirmed metal-line emitter at such low-luminosity and redshift without Ly
α
emission—suggesting that, at least in some cases, a non-uniform covering factor of the neutral gas might hamper the Ly
α
detection.
Oleanolic acid (OA), a natural component of many plant food and medicinal herbs, is endowed with a wide range of pharmacological properties whose therapeutic potential has only partly been exploited ...until now. Throughout complex and multifactorial mechanisms, OA exerts beneficial effects against diabetes and metabolic syndrome. It improves insulin response, preserves functionality and survival of β-cells, and protects against diabetes complications. OA may directly modulate enzymes connected to insulin biosynthesis, secretion, and signaling. However, its major contributions appear to be derived from the interaction with important transduction pathways, and many of its effects are consistently related to activation of the transcription factor Nrf2. Doing that, OA induces the expression of antioxidant enzymes and phase II response genes, blocks NF-κB, and represses the polyol pathway, AGEs production, and hyperlipidemia. The management of type 2 diabetes requires an integrated approach, which includes the early intervention to prevent or delay the disease progression, and the use of therapies to control glycemia and lipidemia in its late stages. In this sense, the use of functional foods or drugs containing OA is, undoubtedly, an interesting path.
The emergence of passive galaxies in the early Universe results from the delicate interplay among the different physical processes responsible for their rapid assembly and the abrupt shut-down of ...their star formation activity. Investigating the individual properties and demographics of early passive galaxies improves our understanding of these mechanisms. In this work we present a follow-up analysis of the
z
> 3 passive galaxy candidates selected by Merlin et al. (2019, MNRAS, 490, 3309) in the CANDELS fields. We begin by first confirming the accuracy of their passive classification by exploiting their sub-millimetre emission to demonstrate the lack of ongoing star formation. Using archival ALMA observations we are able to confirm at least 61% of the observed candidates as passive. While the remainder lack sufficiently deep data for confirmation, we are able to validate the entire sample in a statistical sense. We then estimate the stellar mass function (SMF) of all 101 passive candidates in three redshift bins from
z
= 5 to
z
= 3. We adopt a stepwise approach that has the advantage of taking into account photometric errors, mass and selection completeness issues, as well as the Eddington bias, without any a posteriori correction. We observe a pronounced evolution in the SMF around
z
∼ 4, indicating that we are witnessing the emergence of the passive population at this epoch. Massive (
M
> 10
11
M
⊙
) passive galaxies, only accounting for a small (< 10%) fraction of galaxies at
z
> 4, become dominant at later epochs. Thanks to a combination of photometric quality, sample selection, and methodology, we overall find a higher density of passive galaxies than in previous works. The comparison with theoretical predictions, despite a qualitative agreement (at least for some of the models considered), denotes a still incomplete understanding of the physical processes responsible for the formation of these galaxies. Finally, we extrapolate our results to predict the number of early passive galaxies expected in surveys carried out with future facilities.
Abstract
We present the first rest-frame optical size–luminosity relation of galaxies at
z
> 7, using the NIRCam imaging data obtained by the GLASS James Webb Space Telescope Early Release Science ...(GLASS-JWST-ERS) program, providing the deepest extragalactic data of the ERS campaign. Our sample consists of 19 photometrically selected bright galaxies with
m
F444W
≤ 27.8 at 7 <
z
< 9 and
m
F444W
< 28.2 at
z
∼ 9−15. We measure the size of the galaxies in five bands, from rest-frame optical (∼4800 Å) to the UV (∼1600 Å) based on the Sérsic model, and analyse the size–luminosity relation as a function of wavelength. Remarkably, the data quality of the NIRCam imaging is sufficient to probe the half-light radius
r
e
down to ∼100 pc at
z
> 7. Given the limited sample size and magnitude range, we first fix the slope to that observed for larger samples in rest-frame UV using Hubble Space Telescope samples. The median size
r
0
at the reference luminosity
M
= −21 decreases slightly from rest-frame optical (600 ± 80 pc) to UV (450 ± 130 pc). We then refit the size–luminosity relation allowing the slope to vary. The slope is consistent with
β
∼ 0.2 for all bands except F150W, where we find a marginally steeper slope of
β
= 0.53 ± 0.15. The steep UV slope is mainly driven by the smallest and faintest galaxies. If confirmed by larger samples, it implies that the UV size–luminosity relation breaks toward the faint end, as suggested by lensing studies.
Context. Finding the sources responsible for the hydrogen reionization is one of the most pressing issues in observational cosmology. Bright quasi-stellar objects (QSOs) are known to ionize their ...surrounding neighborhood, but they are too few to ensure the required HI ionizing background. A significant contribution by faint active galactic nuclei (AGNs), however, could solve the problem, as recently advocated on the basis of a relatively large space density of faint active nuclei at z > 4. Aims. This work is part of a long-term project aimed at measuring the Lyman Continuum escape fraction for a large sample of AGNs at z ~ 4 down to an absolute magnitude of M1450 ~ −23. We have carried out an exploratory spectroscopic program to measure the HI ionizing emission of 16 faint AGNs spanning a broad U − I color interval, with I ~ 21–23, and 3.6 < z < 4.2. These AGNs are three magnitudes fainter than the typical SDSS QSOs (M1450 ≲−26) which are known to ionize their surrounding IGM at z ≳ 4. Methods. We acquired deep spectra of these faint AGNs with spectrographs available at the VLT, LBT, and Magellan telescopes, that is, FORS2, MODS1-2, and LDSS3, respectively. The emission in the Lyman Continuum region, close to 900 Å rest frame, has been detected with a signal to noise ratio of ~10–120 for all 16 AGNs. The flux ratio between the 900 Å rest-frame region and 930 Å provides a robust estimate of the escape fraction of HI ionizing photons. Results. We have found that the Lyman Continuum escape fraction is between 44 and 100% for all the observed faint AGNs, with a mean value of 74% at 3.6 < z < 4.2 and − 25.1 ≲ M1450 ≲−23.3, in agreement with the value found in the literature for much brighter QSOs (M1450 ≲−26) at the same redshifts. The Lyman Continuum escape fraction of our faint AGNs does not show any dependence on the absolute luminosities or on the observed U − I colors of the objects. Assuming that the Lyman Continuum escape fraction remains close to ~75% down to M1450 ~ − 18, we find that the AGN population can provide between 16 and 73% (depending on the adopted luminosity function) of the whole ionizing UV background at z ~ 4, measured through the Lyman forest. This contribution increases to 25–100% if other determinations of the ionizing UV background are adopted from the recent literature. Conclusions. Extrapolating these results to z ~ 5–7, there are possible indications that bright QSOs and faint AGNs can provide a significant contribution to the reionization of the Universe, if their space density is high at M1450 ~ −23.
Introduction: The onset of puberty in females is highly sensitive to the nutritional status and the amount of energy reserves of the organism. This metabolic information is sensed and transmitted to ...hypothalamic GnRH neurons, considered to be ultimately responsible for triggering puberty through the coordinated action of different peripheral hormones, central neurotransmitters, and molecular mediators.
Areas covered: This article will review and discuss (i) the relevant actions of the adipose hormone leptin, as a stimulatory/permissive signal, and the gut hormone ghrelin, as an inhibitory factor, in the metabolic control of female puberty; (ii) the crucial role of the hypothalamic kisspeptin neurons, recently emerged as essential gatekeepers of puberty, in transmitting this metabolic information to GnRH neurons; and (iii) the potential involvement of key cellular energy sensors, such as mTOR, as molecular mediators in this setting.
Expert opinion: The thorough characterization of the physiological roles of the above elements in the metabolic control of female puberty, along with the discovery of novel factors, pathways, and mechanisms involved, will promote our understanding of the complex networks connecting metabolism and puberty and, ultimately, will aid in the design of target-specific treatments for female pubertal disorders linked to conditions of metabolic stress.
HSP70‐HSP90 organizing protein (HOP) is a family of cytosolic cochaperones whose molecular role in thermotolerance is quite unknown in eukaryotes and unexplored in plants.
In this article, we ...describe that the three members of the AtHOP family display a different induction pattern under heat, being HOP3 highly regulated during the challenge and the attenuation period. Despite HOP3 is the most heat‐regulated member, the analysis of the hop1 hop2 hop3 triple mutant demonstrates that the three HOP proteins act redundantly to promote long‐term acquired thermotolerance in Arabidopsis. HOPs interact strongly with HSP90 and part of the bulk of HOPs shuttles from the cytoplasm to the nuclei and to cytoplasmic foci during the challenge. RNAseq analyses demonstrate that, although the expression of the Hsf targets is not generally affected, the transcriptional response to heat is drastically altered during the acclimation period in the hop1 hop2 hop3 triple mutant. This mutant also displays an unusual high accumulation of insoluble and ubiquitinated proteins under heat, which highlights the additional role of HOP in protein quality control. These data reveal that HOP family is involved in different aspects of the response to heat, affecting the plant capacity to acclimate to high temperatures for long periods.
Heat is one of the environmental stresses that most drastically impact on plant growth, development and yield. This article describes for the first time that HOPs (HSP70‐1152 HSP90 organizing proteins) play a main role in long term acquired thermotolerance, affecting different aspects of this complex response