Griffithsin is an algae-derived lectin with strong anti-viral activity against HIV and a positive safety profile. Multiple clinical studies are investigating griffithsin's utility as topical HIV ...microbicide. HIV microbicides are an extremely cost-sensitive market and plant-based griffithsin protein expression has the potential to meet those demands. The griffithsin product used in the clinic has been expressed and purified in
, using a TMV-based viral vector system, Geneware®. Outdoor pharming of biopharmaceuticals would further alleviate startup costs for biotechnology firms and may allow broader product accessibility. Therefore, this study assessed expression in a hybrid tobacco line,
, that is susceptible to TMV-based viral vectors and can be grown outdoors. In addition to using this hybrid line we expand on methods for
storage of griffithsin in leafy plants by ensiling kilogram quantities of griffithsin. The ensiling process allows year-round biomanufacturing, minimal environmental-controlled storage, and reduces the industry need for multiple growth areas to maintain multi-product manufacturing of plant-based pharmaceuticals. This study shows that griffithsin can be expressed in
and is stable, recoverable, and active from ensiled tissue. These studies can pave the way for future plant-based pharmaceuticals to be expressed and stored in this manner.
This study evaluates the relationship between elements of a college preparation program and the college readiness of low-income and/or Latina/o students at the completion of 6 years of participation ...in the program. Hours of participation in tutoring, mentoring, advising, college campus visits, summer programs, and educational field trips are examined in relationship to students' college-track course completion and Preliminary SAT (PSAT) participation. In addition, the relationship between students' expectations for college and their ranking of program activities is examined. Results indicate that key program elements related to college readiness include advising, college campus visits, and college information through booklets and speakers.
Celotno besedilo
Dostopno za:
BFBNIB, DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Scholars have cited an antiracist identity as an ideal development status for Whites seeking to change systemic racism (Helms, 1995). However, little is known regarding the lived complexities of ...antiracist work itself. This article examines the experiences of one group of Whites (N = 10) committed to antiracist action. Outcomes indicate challenges that include backlash and struggles to identify more effective antiracist tactics. Coping mechanisms are considered in relation to counseling and counselor training practices.
This article presents findings from a study that explored the lived experiences of Whites committed to antiracism action—those who, according to Janet Helms's (1990, 1995, 2014) White racial identity ...model, exhibit characteristics of the autonomy status. Thematic outcomes indicated participants’ (N = 10) efforts to manage their own racism in ways that are both proactive and responsive in nature. Findings are compared with theoretical and empirical literature regarding the racial identity development of Whites committed to antiracist action.
Este artículo presenta los hallazgos obtenidos a partir de un estudio que exploró las experiencias vitales de personas blancas comprometidas con la acción antirracista. Según el modelo de identidad racial blanca de Janet Helms (1990, 1995, 2014), estas personas son aquellas que muestran características del estado de autonomía. Los resultados temáticos indicaron que los esfuerzos de los participantes (N = 10) por controlar su propio racismo son por naturaleza tanto proactivos como reactivos. Se comparan los hallazgos con la literatura teórica y empírica en torno al desarrollo de la identidad racial de personas blancas comprometidas con la acción antirracista.
This study evaluates the effectiveness of a counselor education program in teaching multicultural counseling knowledge and skills. Standardized examination scores and rater evaluations compare ...multicultural with general counseling knowledge and skill competency for students who completed a counseling master's program. The relationship between multicultural knowledge and multicultural and general skills is examined.
Este estudio evalúa la efectividad de un programa educativo para consejeros a la hora de enseñar conocimientos y habilidades multiculturales en consejería. Se emplean tanto resultados estandarizados de exámenes como evaluaciones docentes para comparar los conocimientos de consejeria y la competencia en habilidades de tipo general con los multiculturales en estudiantes que han completado un Máster en Consejería. Se examina la relación entre conocimientos multiculturales y habilidades generales y multiculturales.
This article presents outcomes of a qualitative exploration of White racial identity. Ten participants whose characteristics were reflective of Helms's () autonomy status defined their racial ...identities and related lifestyle choices. Findings are conceptualized within the framework of Helms's (, ) theory of White racial identity development. Suggestions are intended to enhance White racial identity theory and provide empirical support for characteristics of Whites who are engaged in antiracist activities.
A diverse team of counselor educators used a phenomenological qualitative research method to analyze a social justice group intervention—a town hall meeting among a group of students, educators, and ...mental health professionals that focused on race, justice, and peace. Participants described forms of oppression in their personal and professional lives and strategies to combat them.
There is increasing empirical evidence demonstrating the negative impact of racism and other social injustices on individuals' mental and emotional health. Those findings challenge counselor ...educators and practitioners to address social injustices in professional training programs and communities across the country. This article illustrates a national advocacy project, whereby a group approach is applied to address social injustices. Application of the model is presented, along with a description of the specific group constructs and skills that were used in the intervention.
EFFECTIVE PARENT CONSULTATION IN PLAY THERAPY Cates, Jennifer; Paone, Tina R; Packman, Jill ...
International journal of play therapy,
2006, Letnik:
15, Številka:
1
Journal Article
Recenzirano
Effective communication with caregivers can contribute to successful play
therapy outcomes. This article examines the structure of parent consultation in
play therapy. The components of effective ...parent consultation are outlined, from
the initial phone interview through termination, to provide guidance to play
therapists for communicating with caregivers throughout the therapy
process.
Desmoid type fibromatosis(DTF) is a rare, locally invasive, non-metastasizing soft tissue tumor. We report an interesting case of DTF involving the pancreatic head of a 54-year-old woman. She ...presented with intermittent dysphagia and significant weight loss within a 3-mo period. Laboratory findings showed mild elevation of transaminases, significant elevation of alkaline phosphatase and direct hyperbilirubinemia, indicating obstructive jaundice. Computerized tomography of the abdomen revealed a mass in the head of the pancreas, dilated common bile duct, and dilated pancreatic duct. Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound showed a large hypoechoic massin the head of the pancreas causing extrahepatic biliary obstruction and pancreatic ductal dilation. The patient underwent a successful partial pancreatico-duodenectomy and cholecystectomy. She received no additional therapy after surgery, and liver function tests were normalized within nine days after surgery. Currently, surgical resection is the recommended first line treatment. The patient will be followed for any recurrence.
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