The purposes of this study were to describe our 16-month experience with onabotulinumtoxinA (OnabotA) for the treatment of chronic migraine (CM) in the Spanish province of Segovia, evaluate its ...benefits, and determine clinical markers of good response to treatment.
Prospective study of patients with CM who received OnabotA for 16 months. The effectiveness of OnabotA was evaluated based on the reduction in the number of headache days, pain intensity, and side effects. We used two-way analysis of variance (ANOVA) to assess the effects of treatment according to the time factor. We studied the correlation between treatment effects and other variables using a linear regression model to establish the clinical markers of good response to treatment.
We included 69 patients who met the diagnostic criteria for CM. Patients underwent an average of 2 infiltrations. Mean age was 43 years; 88.4% were women. The number of headache days and pain intensity decreased significantly (P < .005); improvements remained over time. We found a negative correlation between the reduction in pain intensity and the number of treatments before OnabotA.
The beneficial effects of OnabotA for CM continue over time. OnabotA is a safe and well-tolerated treatment whose use for refractory CM should not be delayed since early treatment provides greater benefits.
Resumen Objetivo Describir la experiencia con la administración de toxina botulínica tipo A (OnabotA) en el tratamiento de la migraña crónica (MC) en Segovia durante 16 meses, evaluar su beneficio y ...buscar marcadores clínicos que sirvan para predecir una mejor respuesta al tratamiento. Pacientes y métodos Estudio prospectivo de pacientes con MC que recibieron infiltraciones con OnabotA durante 16 meses. Se evaluó la eficacia de OnabotA comparando la reducción en el número de días de cefalea, en la intensidad y efectos adversos. Se comparó el efecto del tratamiento con el factor tiempo mediante un análisis de la varianza de dos vías (ANOVA). Se estudió la correlación del efecto del tratamiento con el resto de las variables mediante un modelo de regresión lineal para buscar marcadores clínicos que sirvan para predecir una mejor respuesta. Resultados Se incluyó a 69 pacientes que cumplían criterios de MC. Se les realizó una media de 2 infiltraciones. La edad media fue de 43 años, el 88,4% fueron mujeres. La frecuencia de los días de cefalea y su intensidad se redujeron de forma significativa (p < 0,005) y esta mejoría se mantuvo a lo largo del tiempo. Se encontró una correlación negativa entre la reducción de la intensidad y el número de tratamientos previos a la administración de la toxina. Conclusión El efecto beneficioso de la OnabotA en la MC se mantiene en el tiempo, siendo un tratamiento seguro y bien tolerado. No debe retrasarse su uso en MC refractaria, ya que su beneficio podría ser mayor cuanto antes se administre.
The COVID-19 pandemic has transformed medical practice and severely disrupted the training of medical residents worldwide. The Spanish Society of Neurology conducted a study to assess its impact on ...the training of neurology residents in Spain.
We performed a descriptive, cross-sectional study through a survey distributed by e-mail to all neurology residents belonging to the Society. The survey included questions on demographic variables, care activity, and personal and educational impact of the pandemic, as well as respondents' expectations for the future of their work in the post-pandemic era.
Of 422 surveys sent, we received a total of 152 responses (36%); 79 respondents (52%) were women and 73 (48%) were men. By year of residency, 51 respondents (33.6%) were in the fourth year, 45 (29.6%) in the third year, 28 (18.4%) in the second year, and 28 (18.4%) in the first year. A total of 139 respondents (90.8%) reported changes in hospital activity, and 126 (82.8%) considered the situation to have had a negative impact on their training, with 99 (64.7%) having lost non-recoverable rotations. Sixty-six percent of respondents (n=101) expressed a desire to extend their residency period.
The pandemic has had an extremely severe impact on all areas of the health system, with trainee physicians being one of the most affected groups. Among neurology residents, the crisis has caused significant shortcomings in their training and clinical activities, through the suspension of specific rotations. A high percentage of respondents wished to extend the residency period.
The neurology training program in Spain, approved in 2006, emphasizes the importance of residents' on-duty shifts supervised by a neurologist. An evaluation of the Specialty National Commission in ...2008 showed an unequal fulfillment of this goal: 60.30% of the training units offered their residents 24-hour shifts with on-duty supervision, and only 43% in their own center. After more than a decade, and a new national training program on design, we would like to know the current situation and possible factors that might be involved.
Cross-sectional study through self-administered surveys to neurology training units that had recently graduated residents (n = 77). Responses were collected between October 2021 and February 2022.
All units answered the survey. In 2021, 88.30% met the supervision objectives, and 83% offered their trainees 24-hour on-duty shifts with a neurologist in their center. Among related factors, there is a significant direct relationship between this kind of shift, the hospital's size, and the existence of a stroke unit.
Residents' guidance during the 24-hour neurology on-duty shifts follows the path set by the training program and the national commission. However, there are still some differences that go beyond purely healthcare aspects. The future national program could establish new guidelines that help us achieve less heterogeneity, in order to offer the same training in the assessment of acute neurological patients.
Experience with botulinum toxin in chronic migraine Castrillo Sanz, A.; Morollón Sánchez-Mateos, N.; Simonet Hernández, C. ...
Neurología (Barcelona, English ed. ),
October 2018, 2018-10-00, 2018-10-01, Letnik:
33, Številka:
8
Journal Article
Recenzirano
Odprti dostop
The purposes of this study were to describe our 16-month experience with onabotulinumtoxinA (OnabotA) for the treatment of chronic migraine (CM) in the Spanish province of Segovia, evaluate its ...benefits, and determine clinical markers of good response to treatment.
Prospective study of patients with CM who received OnabotA for 16 months. The effectiveness of OnabotA was evaluated based on the reduction in the number of headache days, pain intensity, and side effects. We used two-way analysis of variance to assess the effects of treatment according to the time factor. We studied the correlation between treatment effects and other variables using a linear regression model to establish the clinical markers of good response to treatment.
We included 69 patients who met the diagnostic criteria for CM. Patients underwent an average of two infiltrations. Mean age was 43 years; 88.4% were women. The number of headache days and pain intensity decreased significantly (P<.005); improvements remained over time. We found a negative correlation between the reduction in pain intensity and the number of treatments before OnabotA.
The beneficial effects of OnabotA for CM continue over time. OnabotA is a safe and well-tolerated treatment whose use for refractory CM should not be delayed since early treatment provides greater benefits.
Describir la experiencia con la administración de toxina botulínica tipo A (OnabotA) en el tratamiento de la migraña crónica (MC) en Segovia durante 16 meses, evaluar su beneficio y buscar marcadores clínicos que sirvan para predecir una mejor respuesta al tratamiento.
Estudio prospectivo de pacientes con MC que recibieron infiltraciones con OnabotA durante 16 meses. Se evaluó la eficacia de OnabotA comparando la reducción en el número de días de cefalea, en la intensidad y efectos adversos. Se comparó el efecto del tratamiento con el factor tiempo mediante un análisis de la varianza de dos vías (ANOVA). Se estudió la correlación del efecto del tratamiento con el resto de las variables mediante un modelo de regresión lineal para buscar marcadores clínicos que sirvan para predecir una mejor respuesta.
Se incluyó a 69 pacientes que cumplían criterios de MC. Se les realizó una media de 2 infiltraciones. La edad media fue de 43 años, el 88,4% fueron mujeres. La frecuencia de los días de cefalea y su intensidad se redujeron de forma significativa (p<0,005) y esta mejoría se mantuvo a lo largo del tiempo. Se encontró una correlación negativa entre la reducción de la intensidad y el número de tratamientos previos a la administración de la toxina.
El efecto beneficioso de la OnabotA en la MC se mantiene en el tiempo, siendo un tratamiento seguro y bien tolerado. No debe retrasarse su uso en MC refractaria, ya que su beneficio podría ser mayor cuanto antes se administre.
Resumen: Introducción: La pandemia ocasionada por la aparición del SARS-CoV-2, ha transformado la práctica médica, y ha alterado gravemente la formación de los médicos residentes a nivel mundial. ...Desde la Sociedad Española de Neurología (SEN) se ha querido conocer el grado de repercusión que la COVID-19 ha tenido en el ámbito formativo entre los residentes de neurología. Método: Se realizó un estudio descriptivo transversal mediante el envío de una encuesta por email a todos los residentes de neurología miembros de dicha sociedad. Se incluyeron preguntas relativas a aspectos demográficos, actividad asistencial y repercusión a nivel formativo y personal durante la pandemia, así como su previsión sobre el futuro laboral «post-COVID». Resultados: De 422 encuestas, respondió un total de 152 (36%) residentes, 79 mujeres (52%) y 73 varones (48%). La distribución por año de residencia fue R4: 51 (33,6%), R3: 45 (29,6%), R2: 28 (18,4%) y R1: 28 (18,4%). La actividad de hospitalización se vio alterada en 139 (90,8%) casos. Consideraron que la situación afectaría negativamente a su formación 126 (82,8%) residentes, de los que 99 (64,7%) perdieron rotaciones no recuperables. Manifestaron deseo de alargar el periodo de residencia 101 (66%). Conclusiones: La pandemia ha tenido un gravísimo impacto en todo el sistema sanitario, siendo los médicos en formación uno de los colectivos más afectados. En los residentes de neurología ha provocado notables deficiencias de su actividad formativa y asistencial como consecuencia de la suspensión de rotaciones específicas. Un alto porcentaje manifestó deseo de ampliar el periodo de residencia. Abstract: Introduction: The COVID-19 pandemic has transformed medical practice and severely disrupted the training of medical residents worldwide. The Spanish Society of Neurology conducted a study to assess its impact on the training of neurology residents in Spain. Methods: We performed a descriptive, cross-sectional study through a survey distributed by e-mail to all neurology residents belonging to the Society. The survey included questions on demographic variables, care activity, and personal and educational impact of the pandemic, as well as respondents’ expectations for the future of their work in the post-pandemic era. Results: Of 422 surveys sent, we received a total of 152 responses (36%); 79 respondents (52%) were women and 73 (48%) were men. By year of residency, 51 respondents (33.6%) were in the fourth year, 45 (29.6%) in the third year, 28 (18.4%) in the second year, and 28 (18.4%) in the first year. A total of 139 respondents (90.8%) reported changes in hospital activity, and 126 (82.8%) considered the situation to have had a negative impact on their training, with 99 (64.7%) having lost non-recoverable rotations. Sixty-six percent of respondents (n=101) expressed a desire to extend their residency period. Conclusions: The pandemic has had an extremely severe impact on all areas of the health system, with trainee physicians being one of the most affected groups. Among neurology residents, the crisis has caused significant shortcomings in their training and clinical activities, through the suspension of specific rotations. A high percentage of respondents wished to extend the residency period.
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There is no international consensus on the definition of the type of oncological resection that corresponds to each of the colectomies existing in the current literature.
The ...objective is to define for each colectomy described in the literature: embryological dissection plane, vascular pedicles in which to perform central ligation, the extent of the colectomy, and the need for resection of the greater momentum.
A consensus of experts is carried out through the Delphi methodology through two rounds from the Coloproctology Section of the Spanish Association of Surgeons. Study period: November 2021-January 2023. 120 experts were surveyed.
Degrees of consensus: Very strong: >90%, Strong: 80%–90%, Moderate: 50%–80%, No consensus: <50%.
The definition for each oncological colectomy was established by very strong, and strong recommendations.
Each oncological colectomy was established as Right hemicolectomy (RHC), RHC with D3 lymphadenectomy, Extended-RHC, transverse colon segmental colectomy, splenic flexure segmental colectomy, subtotal colectomy, total colectomy, left hemicolectomy (LHC), extended-LHC, sigmoidectomy.
No existe consenso internacional en la definición del tipo de resección oncológica que corresponde a cada una de las colectomías existentes en la bibliografía actual.
El objetivo es definir para cada colectomía descrita en la literatura: plano de disección embriológico, pedículos vasculares en los que realizar ligadura central, la extensión de la colectomía y la necesidad de resección de epiplón mayor.
Se realiza un Consenso de expertos a través de la metodología Delphi mediante dos rondas desde la Sección Coloproctología de Asociación Española de Cirujanos. Período de estudio: noviembre 2021-enero 2023. Fueron encuestados 120 expertos.
Grados de consenso: Muy fuerte: >90%, Fuerte: 80%–90%, Moderado: 50%–80%, No consenso: <50%.
La definición para cada colectomía oncológica quedó establecida mediante recomendaciones muy fuertes y fuertes.
Colectomías definidas: hemicolectomía derecha (HCD), HCD con linfadenectomía D3, HCD-ampliada, colectomía segmentaria de colon transverso, resección segmentaria ángulo esplénico, colectomía subtotal, total, hemicolectomía izquierda (HCI), HCI-ampliada y sigmoidectomía.
La pandemia ocasionada por la aparición del SARS-CoV-2, ha transformado la práctica médica, y ha alterado gravemente la formación de los médicos residentes a nivel mundial. Desde la Sociedad Española ...de Neurología (SEN) se ha querido conocer el grado de repercusión que la COVID-19 ha tenido en el ámbito formativo entre los residentes de neurología.
Se realizó un estudio descriptivo transversal mediante el envío de una encuesta por email a todos los residentes de neurología miembros de dicha sociedad. Se incluyeron preguntas relativas a aspectos demográficos, actividad asistencial y repercusión a nivel formativo y personal durante la pandemia, así como su previsión sobre el futuro laboral «post-COVID».
De 422 encuestas, respondió un total de 152 (36%) residentes, 79 mujeres (52%) y 73 varones (48%). La distribución por año de residencia fue R4: 51 (33,6%), R3: 45 (29,6%), R2: 28 (18,4%) y R1: 28 (18,4%). La actividad de hospitalización se vio alterada en 139 (90,8%) casos. Consideraron que la situación afectaría negativamente a su formación 126 (82,8%) residentes, de los que 99 (64,7%) perdieron rotaciones no recuperables. Manifestaron deseo de alargar el periodo de residencia 101 (66%).
La pandemia ha tenido un gravísimo impacto en todo el sistema sanitario, siendo los médicos en formación uno de los colectivos más afectados. En los residentes de neurología ha provocado notables deficiencias de su actividad formativa y asistencial como consecuencia de la suspensión de rotaciones específicas. Un alto porcentaje manifestó deseo de ampliar el periodo de residencia.
The COVID-19 pandemic has transformed medical practice and severely disrupted the training of medical residents worldwide. The Spanish Society of Neurology conducted a study to assess its impact on the training of neurology residents in Spain.
We performed a descriptive, cross-sectional study through a survey distributed by e-mail to all neurology residents belonging to the Society. The survey included questions on demographic variables, care activity, and personal and educational impact of the pandemic, as well as respondents’ expectations for the future of their work in the post-pandemic era.
Of 422 surveys sent, we received a total of 152 responses (36%); 79 respondents (52%) were women and 73 (48%) were men. By year of residency, 51 respondents (33.6%) were in the fourth year, 45 (29.6%) in the third year, 28 (18.4%) in the second year, and 28 (18.4%) in the first year. A total of 139 respondents (90.8%) reported changes in hospital activity, and 126 (82.8%) considered the situation to have had a negative impact on their training, with 99 (64.7%) having lost non-recoverable rotations. Sixty-six percent of respondents (n=101) expressed a desire to extend their residency period.
The pandemic has had an extremely severe impact on all areas of the health system, with trainee physicians being one of the most affected groups. Among neurology residents, the crisis has caused significant shortcomings in their training and clinical activities, through the suspension of specific rotations. A high percentage of respondents wished to extend the residency period.
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