BiFeO
3
/BiVO
4
heterojunction photocatalysts were synthesized by a hydrothermal method. The structures and optical properties of the as-prepared products were characterized by X-ray diffraction ...(XRD), scanning electron microscopy (SEM), field-emission transmission electron microscopy (TEM), and UV-vis absorption spectroscopy, respectively. The photocatalytic performances of the as-synthesized products were thoroughly evaluated
via
the degradation of Rhodamine B (RhB) under visible light irradiation. Experimental results showed that 50% mole ratio of BiFeO
3
to BiFeO
3
/BiVO
4
photocatalyst exhibited the highest photocatalytic activity compared to other as-prepared products. Moreover, the stability of the as-prepared photocatalyst during the photocatalytic process was also investigated. In addition, the enhanced photocatalytic activity of the as-prepared products could be probably ascribed to the high separation efficiency of the photogenerated electron-hole pairs generated at the heterojunction between BiFeO
3
and BiVO
4
.
BiFeO
3
/BiVO
4
heterojunction photocatalysts were synthesized by a hydrothermal method.
Botulinum neurotoxins (BoNTs), the causative agents for life-threatening human disease botulism, have been recognized as biological warfare agents. Monoclonal antibody (mAb) therapeutics hold ...considerable promise as BoNT therapeutics, but the potencies of mAbs against BoNTs are usually less than that of polyclonal antibodies (or oligoclonal antibodies). The confirmation of key epitopes with development of effective mAb is urgently needed.
We selected 3 neutralizing mAbs which recognize different non-overlapping epitopes of BoNT/B from a panel of neutralizing antibodies against BoNT/B. By comparing the neutralizing effects among different combination groups, we found that 8E10, response to ganglioside receptor binding site, could synergy with 5G10 and 2F4, recognizing non-overlapping epitopes within Syt II binding sites. However, the combination of 5G10 with 2F4 blocking protein receptor binding sites did not achieve synergistical effects. Moreover, we found that the binding epitope of 8E10 was conserved among BoNT A, B, E, and F, which might cross-protect the challenge of different serotypes of BoNTs in vivo.
The combination of two mAbs recognizing different receptors' binding domain in BoNTs has a synergistic effect. 8E10 is a potential universal partner for the synergistical combination with other mAb against protein receptor binding domain in BoNTs of other serotypes.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Nano-sized ZnO particles were synthesised by a direct precipitation, a sol-gel, and a hydrothermal method. The structures, morphology, and optical properties of these ZnO nanoparticles were ...characterised by XRD, SEM and UV-vis spectroscopy. The photocatalytic activities of the synthesised ZnO nanoparticles were evaluated by the degradation of methyl orange (MO) in an aqueous solution. These experimental results showed that the photodegradation efficiency of MO solutions irradiated by UV for 120 min with ZnO nanoparticles used as catalysts, which were fabricated by a direct precipitation method, could reach 94.59%. The higher photocatalytic activity of MO solutions by the ZnO nanoparticles synthesised by the direct precipitation method is probably due to the spherical ZnO nanoparticles with a smaller crystallite size.
Drought-flood abrupt alternation (DFAA) refers to the rapid transformation between droughts and floods, posing serious threats to ecological security, food production, and human safety. Previous ...studies have insufficiently investigated DFAA events at large regional scales using high-resolution observations and model simulations. In this study, the standardized precipitation evapotranspiration index was used to construct the DFAA magnitude index, which considers the asymmetric effects of drought and flood alternations. Four types of DFAA events were then investigated using high-resolution station observations and NEX-GDDP-CMIP6 model simulations. The results showed that hotspot areas of drought-flood and flood-drought alternation events were mainly in the northern and eastern parts of China, while the hotspot areas of drought-flood-drought and flood-drought-flood alternation events were obviously smaller than those of drought-flood and flood-drought alternation events. Drought-flood, flood-drought, and drought-flood-drought alternation events showed significant upward trends at rates of 0.075, 0.057, and 0.051 events/decade, respectively, and these increases were attributed to significant increases in moderate, severe, and extreme events across China during 1981–2020. Generally, the total number of DFAA events above moderate grade in the northern, central, and some areas in the southern parts of China increased obviously (>50 %) during 2001–2020 compared to 1981–2000. NEX-GDDP-CMIP6 can reasonably represent the multi-year averages and long-term trends of precipitation, temperature, and DFAA events in China. Except for the flood-drought-flood alternation events, the other three types of DFAA events showed significant increasing trends in the future, with higher rates under the SSP585 scenario than under the SSP245 scenario (e.g., drought-flood alternation events at rates of 0.033 and 0.046 events/decade under SSP245 and SSP585, respectively, during 1981–2100). DFAA events above the moderate grade were predicted to increase significantly in both 2032–2065 and 2066–2099 compared to 1981–2014, especially in northern China for the 2066–2099 under the SSP585 scenario.
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•DFAA events are likely to occur in the northern and eastern parts of China.•There were general upward trends of DFAA events across China from 1981 to 2020.•NEX-GDDP-CMIP6 can reasonably represent the precipitation, temperature, and DFAA events.•DFAA events are predicted to increase significantly, especially in northern China under SSP585.
Ferroelectric composite thin films of x·C18A-HSBT/PVDF with different C18A-HSBT content (weight ratio of C18A-HSBTto PVDF, x=2.5%, 5%, 7.5%, 10%) were prepared by spin-coating method. The crystal ...structures of x·C18A-HSBT/PVDFthin films were analyzed by X-ray diffraction (XRD) measurements together with Fourier transform-infrared spectroscopy(FT-IR). The morphological studies of these samples were done via scanning electron microscopy (SEM). Experimental resultsdemonstrated that both β-phase of PVDF and the layered perovskite C18A-HSBT co-existed in the x·C18A-HSBT/PVDF thinfilm samples. With an increase of C18A-HSBT content in the x·C18A-HSBT/PVDF thin films, both the dielectric constant andsaturated polarizations were also increased. In addition, as the C18A-HSBT content increased, the leakage current density ofthe x·C18A-HSBT/PVDF thin films under the applied electric field was decreased. KCI Citation Count: 0
In this study, Sb-doping with the procedure of shear exfoliation was adopted in order to improve the thermoelectric performance of Bi2O2Se. It is found that Sb-doping could further increase the ...electron concentration and mobility, leading to a high electrical conductivity. (e.g., 517 S cm−1 of Bi1.96Sb0.04O2Se at room temperature) Besides, thermal conductivity had been inhibited to 0.6 Wm-1 K−1 at 770 K for the sample Bi1.99Sb0.01O2Se. Finally, a peak ZT of around 0.59 at 773 K was achieved for the sample Bi1.98Sb0.02O2Se, which is about 1.8 times larger than that of un-doped one. The results indicate that Sb-doping with the procedure of shear exfoliation could optimize the thermoelectric performance of Bi2O2Se noticeably.
•Sb-doping with the procedure of shear exfoliation could improve the thermoelectric performance of Bi2O2Se effectively.
In the present work, an artificial designed composition defects coupled with liquid-phase mechanical exfoliation (LME) was introduced to improve the thermoelectric performance of Bi2O2Se. The results ...indicate that non-stoichiometric of Bi2O2Se with LME could induce high grain orientation. Moreover, the electrical conductivity of Bi2O2-xSe1+x with LME have been greatly improved due to both higher carrier concentration and holes mobility. In contrast, a relatively low thermal conductivity had been retained. Finally, A high ZTpeak of around 0.54 at 773 K was obtained for the sample Bi2O1.96Se1.04 with LME, which is a new ZT record of Bi2O2Se based thermoelectrics.
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The novel visible light-induced g-C3N4/BiFeO3 composites were successfully synthesized by introducing BiFeO3 into polymeric g-C3N4. The structures and optical properties of composites were ...characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), field-emission transmission electron microscope (TEM), UV–vis diffuse reflection spectroscopy (DRS), respectively. For the degradation of Rhodamine B (RhB), the g-C3N4/BiFeO3 composites exhibited significantly higher visible light photocatalytic activity than that of a single semiconductor. The optimal percentage of doped g-C3N4 was 50%. Both photooxidation and photoreduction processes follow first order kinetics. In addition, the stability of the prepared photocatalyst in the photocatalytic process was also investigated. The enhanced photocatalytic performance could be due to the high separation efficiency of the photogenerated electron–holes pairs. The possible photocatalytic mechanism of g-C3N4/BiFeO3 was proposed to guide the further improvement of their photocatalytic activity.
In this study, the thermoelectric properties of Bi2O2Se-x%AgSnSe2 composites via liquid assisted shear exfoliation- restacking (LASE-R) method were investigated. The results show that Ag can diffuse ...into Bi2O2Se to further improve the electron content and the electrical conductivity. Meanwhile, the absolute Seebeck coefficient gets a little deterioration with an increase in the electron content and the effective mass. Besides, the rest AgSnSe2 can further reduce the lattice thermal conductivity of Bi2O2Se through enhanced interfaces and mass fluctuation scattering of the phonons by compositing with AgSnSe2. Finally, a ZTmax of 0.58 for Bi2O2Se-1%AgSnSe2 was obtained, which is 1.24 times that of Bi2O2Se.
•It is the first time to study the effects of AgSnSe2 addition with LASE-R process.•The σ of Bi2O2Se-x%AgSnSe2 composites was improved by the diffusion of Ag•The κl of Bi2O2Se was inhibited successfully by compositing with AgSnSe2.
The novel COVID-19 outbreak has affected more than 200 countries and territories as of March 2020. Given that patients with cancer are generally more vulnerable to infections, systematic analysis of ...diverse cohorts of patients with cancer affected by COVID-19 is needed. We performed a multicenter study including 105 patients with cancer and 536 age-matched noncancer patients confirmed with COVID-19. Our results showed COVID-19 patients with cancer had higher risks in all severe outcomes. Patients with hematologic cancer, lung cancer, or with metastatic cancer (stage IV) had the highest frequency of severe events. Patients with nonmetastatic cancer experienced similar frequencies of severe conditions to those observed in patients without cancer. Patients who received surgery had higher risks of having severe events, whereas patients who underwent only radiotherapy did not demonstrate significant differences in severe events when compared with patients without cancer. These findings indicate that patients with cancer appear more vulnerable to SARS-CoV-2 outbreak. SIGNIFICANCE: Because this is the first large cohort study on this topic, our report will provide much-needed information that will benefit patients with cancer globally. As such, we believe it is extremely important that our study be disseminated widely to alert clinicians and patients.
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