In search of high-performance field-effect transistors (FETs) made of atomic thin semiconductors, indium selenide (InSe) has held great promise because of its high intrinsic mobility and moderate ...electronic band gap (1.26 eV). Yet the performance of InSe FETs is decisively determined by the surface oxidation of InSe taking place spontaneously in ambient conditions, setting up a mobility ceiling and causing an uncontrollable current hysteresis. Encapsulation by hexagonal boron nitride (h-BN) has been currently used to cope with this deterioration. Here, we provide insights into the role of surface oxides played in device performance and introduce a dry-oxidation process that forms a dense capping layer on top, where InSe FETs exhibit a record-high two-probe mobility of 423 cm2/V·s at room temperature and 1006 cm2/V·s at liquid nitrogen temperature without the use of h-BN encapsulation or high-κ dielectric screening. Ultrahigh on/off current ratio of >108 and current density of 365 μA/μm can be readily achieved without elaborate engineering of drain/source contacts or gating technique. Thickness-dependent device properties are also studied, with optimized performance shown in FETs comprising of 13 nm thick InSe. The high performance of InSe FETs with ultrathin dry oxide is attributed to the effective unpinning of the Fermi level at the metal contacts, resulting in a low Schottky barrier height of 40 meV in an optimized channel thickness.
A novel redox-active quinone-based organic building block 1,4-dicyano-2,3,5,6-tetrahydroxybenzene (LH
4
) has been synthesized and used as a bridging ligand to form a new 1D copper-benzoquinoid ...coordination polymer CuL(DMF)
2
n
. The compound is able to deliver an initial capacity as high as 268 mA h g
−1
at 30 mA g
−1
(∼C/2.5) when used as the cathode in Li batteries.
Ex situ
XPS and FT-IR reveal the involvement of both Cu and organic moieties in the multi-electron redox reaction. Cu K-edge XANES and EXAFS measurements confirm the change in the oxidation state and coordination environment of Cu during the discharge-charge process.
In situ
generated metallic nanoparticles have been observed by TEM. The obtained mechanistic understanding of the metal-organic electrode materials for Li-based batteries may pave the way for the design of next-generation energy-storage systems.
A novel 1D copper-benzoquinoid coordination polymer with both metal and ligand redox activities delivered a capacity as high as 268 mA h g
−1
.
Studies have confirmed that osteoporosis has been considered as one of the complications of diabetes, and the health hazards to patients are more obvious. This study is mainly based on the Taiwan ...National Health Insurance Database (TNHID). Through the analysis of TNHID, it is shown that the combined treatment of traditional Chinese medicine (TCM) medicine in patients of diabetes with osteoporosis (T2DOP) with lower related risks.
According to the study design, 3131 patients selected from TNHID who received TCM treatment were matched by 1-fold propensity score according to gender, age, and inclusion date as the control group. Cox proportional hazards analyzes were performed to compare fracture surgery, hospitalization, and all-cause mortality during a mean follow-up from 2000 to 2015.
A total of 1055/1469/715 subjects (16.85%/23.46%/11.42%) had fracture surgery/inpatient/all-cause mortality of which 433/624/318 (13.83%/19.93%/10.16%) were in the TCM group) and 622/845/397 (19.87%/26.99%/12.68%) in the control group. Cox proportional hazards regression analysis showed that subjects in the TCM group had lower rates of fracture surgery, inpatient and all-cause mortality (adjusted HR = 0.467; 95% CI = 0.225-0.680, P<0.001; adjusted HR = 0.556; 95% CI = 0.330-0.751, P<0.001; adjusted HR = 0.704; 95% CI = 0.476-0.923, P = 0.012). Kaplan-Meier analysis showed that the cumulative risk of fracture surgery, inpatient and all-cause mortality was significantly different between the case and control groups (all log-rank p<0.001).
This study provides longitudinal evidence through a cohort study of the value of integrated TCM for T2DOP. More research is needed to fully understand the clinical significance of these results.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Metal-organic-based electrode materials are increasingly appealing because both metal and organic linker are capable of undergoing redox processes, thus offering a high specific capacity. High ...porosity which can be achieved by the rational design of these materials is generally perceived as one of the major criteria for high rate performance. However, while Li-ion transport may be possible, oftentimes the counteranions (
e.g.
, PF
6
−
) and solvent molecules are co-inserted into the porous host lattice, potentially hindering Li-ion diffusion pathways. Here we propose the concept of close-packed metal-organic cathode stabilized by multiple supramolecular interactions as a viable solution for exceptional electrochemical performance. This is illustrated in a modularly designed redox-active CuL(Py)
2
n
(LH
4
= 1,4-dicyano-2,3,5,6-tetrahydroxybenzene, Py = pyridine). The mechanistic studies and DFT calculations confirm that the supramolecular interactions between its close-packed chains are the key to the flexible host lattice which only allows desolvated Li
+
to intercalate, while these weak bonds also stabilize the inserted Li in the preferred hopping sites, creating optimal diffusion paths. The performance observed in this work is found to be among the best ever reported for metal-organic cathodes with a capacity as high as 255 mA h g
−1
at 65 mA g
−1
(0.25C) and a reversible capacity of 59 mA h g
−1
at ∼26 A g
−1
(100C) corresponding to 81% retention after 1000 cycles. These findings reveal a potential new strategy towards metal-organic-based electrodes with high performance and enhanced cycling stability.
Supramolecular interactions have been found to be essential for exceptional electrochemical performance of a close-packed metal-organic-based cathode, considered one of the best ever reported.
Antiretroviral therapy (ART) can restore protective immune responses against opportunistic infections (OIs) and reduce mortality in patients with human immunodeficiency virus (HIV) infections. Some ...patients treated with ART may develop immune reconstitution inflammatory syndrome (IRIS).
complex (MAC)-related IRIS most commonly presents as lymphadenitis, soft-tissue abscesses, and deteriorating lung infiltrates. However, neurological presentations of IRIS induced by MAC have been rarely described. We report the case of a 31-year-old man with an HIV infection. He developed productive cough and chronic inflammatory demyelinating polyneuropathy (CIDP) three months after the initiation of ART. He experienced an excellent virological and immunological response. Sputum culture grew MAC. The patient was diagnosed with MAC-related IRIS presenting as CIDP, based on his history and laboratory, radiologic, and electrophysiological findings.
: Neurological symptoms improved after plasmapheresis and intravenous immunoglobulin (IVIG) treatment. To our knowledge, this is the first reported case of CIDP due to MAC-related IRIS. Clinicians should consider MAC-related IRIS in the differential diagnosis of CIDP in patients with HIV infections following the initiation of ART.
A simple, low cost technique to fabricate a plastic optical fiber sensor for dual sensing of temperature and oxygen has been described. The optical fiber dual sensor consists of temperature and ...oxygen indicators that were coated on the fiber end. A fluorinated xerogels doped with platinum tetrakis pentrafluoropheny porphine (PtTFPP) and 5(6)-carboxyfluorescein (CF) serves as the oxygen and temperature sensing material. The temperature and oxygen indicators can both be excited with an LED of 405nm, and the two emission wavelengths can be detected separately. The optical fiber dual sensor has been tested with regard to monitoring different temperatures and oxygen concentrations. The typical Stern–Volmer plot of an optical fiber dual sensor for oxygen sensing shows linearity, and the attenuation of the relative luminescence intensity for temperature sensing also has a linear relationship with temperature in the tested range. In addition, our results show that the luminescence properties of the temperature sensor are independent of the presence of the oxygen sensor, and have a uniquely good linear response in the 25–66°C range. Finally, the oxygen sensing scheme presented in this work is intended for use in temperature compensation, and optical fiber dual sensor can be used for the contactless-sensing of temperature and oxygen in biological, medical and environmental applications.
A new voltage sensing method, named Information Acquisition of Pulsating Voltage (IAPV), is proposed in this paper to improve the accuracy of voltage measurement for the electric motor emulator ...(EME). In the EME, the widely used conventional voltage sensing (CVS) method with low-pass filters and analog-to-digital conversion (ADC) in digital signal processors (DSP) is susceptible to phase delay and noise. To deal with the disadvantage of the CVS method, the IAPV method is introduced with the pulsating voltage signal digitally transmitted and directly processed by the DSP. Simulations and hardware experiments are performed to validate the proposed IAPV method. Based on the experimental results, the proposed IAPV method can achieve smaller errors by comparing it to the CVS method. It is also applicable in the EME to obtain accurate voltage information.
Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated.
We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold ...(SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females.
Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM.
Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM.
This study employs laboratory model tests for backfill grouting and numerical analyses (coupled analysis of the discrete element method and computational fluid dynamics, DEM-CFD coupling analysis) to ...investigate the feasibility of constructing a cut-off dam inside a water-filled circular tunnel using the backfill grouting method from the ground surface. Several improved backfill methods were studied to enhance the effectiveness of the cut-off dam. These methods include: (a) adding an additional backfill grouting hole between the double-row cut-off dam and applying pressurized grouting; (b) adjusting the number of backfill grouting holes per row of the cut-off dam; (c) simultaneously grouting the double-row cut-off dams to minimize the formation of interface fissures and voids; (d) adjusting the grout hole spacing of the double-row cut-off dams to reduce the volume of backfill material. Additionally, pressurized mortar grouting is a critical mass to ensure the water tightness of the cut-off dam. The implementation of these backfilling arrangements improves the effectiveness and watertight of the cut-off dam, thereby reducing the construction time and cost. The findings of this study can serve as a reference for water-filled tunnels and subsequent rehabilitation works in the future.
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