Lithium-ion batteries safety is an issue that should be solved. The thermal stability of Li{sub 0.5}CoO{sub 2} in the presence of solvents/electrolyte and LiPF{sub 6} salt were studied by using C80 ...micro-calorimeter in this paper. It was found that the thermal stability of Li{sub 0.5}CoO{sub 2} either in the presence of cyclic carbonate or linear carbonate is decreased greatly, especially for the linear carbonate-Li{sub 0.5}CoO{sub 2} coexisting system, and the thermal stability of dimethyl carbonate-Li{sub 0.5}CoO{sub 2} coexisting system is the least stable one. LiPF{sub 6} can prevent oxygen releasing from Li{sub 0.5}CoO{sub 2} at low temperature, but the delayed reaction will generate more heat at higher temperature. At last, thermal stability of two kinds of electrolytes with Li{sub 0.5}CoO{sub 2} was explored. The LiPF{sub 6}/ethylene carbonate + dimethyl carbonate + ethylmethyl carbonate-Li{sub 0.5}CoO{sub 2} system shows less thermal stability, which is attributed to the activity between dimethyl carbonate and Li{sub 0.5}CoO{sub 2}, as well as agree with the thermal experiment on dimethyl carbonate-Li{sub 0.5}CoO{sub 2} coexisting system.
Inhibitory Effects of 3,5-O-Dicaffeoyl-epi-quinic Acid from Gymnaster koraiensis on AKR1B10 Lee, J.Y., Natural Products Research Center, Korea Institute of Science and Technology Gangneung Institute, Gangneung, Republic of Korea; Song, D.G., Natural Products Research Center, Korea Institute of Science and Technology Gangneung Institute, Gangneung, Republic of Korea; Lee, E.H., Natural Products Research Center, Korea Institute of Science and Technology Gangneung Institute, Gangneung, Republic of Korea ...
Applied biological chemistry,
12/2009, Letnik:
52, Številka:
6
Journal Article
Recenzirano
Odprti dostop
AKR1B10 is a human NADPH-dependent aldo-keto reductase family 1 B10, which has been considered as a potential cancer therapeutic target. 3,5-O-Dicaffeoyl-epi-quinic acid (3,5-DCQA) was isolated from ...ethyl acetate fraction of Gymnaster koraiensis (Nakai) Kitam as an AKR1B10 inhibitor. 3,5-DCQA inhibited the activity of recombinant human AKR1B10 (rhAKR1B10) with its IC∧50 value of 1.2 μM and its inhibition mode was uncompetitive from enzyme kinetic analysis.
Inhibitory Effects of 23 Korean Local Plant Extracts on Aldo-keto reductase family 1 B10 (AKR 1 B10) Lee, J.Y., Natural Products Research Center, KIST Gangneung Institute, Gangneung, Republic of Korea; Song, D.G., Natural Products Research Center, KIST Gangneung Institute, Gangneung, Republic of Korea; Jung, S.H., Natural Products Research Center, KIST Gangneung Institute, Gangneung, Republic of Korea ...
Korean Journal of Pharmacognosy,
(Sep 2009), Letnik:
40, Številka:
3
Journal Article
Recenzirano
We examined ethanol extracts prepared from 23 Korean local plants obtained in Pyeongchang, Gangwon-do for their inhibitory effects on recombinant human AKR 1 B10 (rhAKR1B10) in vitro. To do this, ...rhAKR1B10 was first expressed in E. coli as a biological active form and purified by using Ni-affinity chromatography followed by gel permeation chromatography. Then, rhAKR1B10 was used for screening out 23 Korean local plant extracts having an inhibitory activity against itself. Among them, six extracts showed more than 50% inhibition of rhAKR1B10 activity at the concentration of 10 ㎍/ml. Especially, the extracts of Ligularia fischeri var. spiciformis Nakai and Rhus trichocarpa Miq. were the most potent because their IC∧50 values were 2.94 and 2.00 ㎍/ml, respectively.
Six new serovarieties of B. thuringiensis carrying specific H-antigen have minor differences in biochemical characteristics and morphological characteristics of crystals, which are commonly resistant ...against four antibiotics. The B. thuringiensis serovar. coreanensis is nontoxic to silkworm larvae, but it is moderately toxic against the Culex pipiens larvae. The B. thuringiensis serovar. konkukian and leesis are nontoxic against mosquitos larvae, but are toxic against silkworm larvae.
Home range size and habitat use of seropositive Oryzomys palustris, primary host for the Bayou strain of hantavirus, were compared to that of seronegative individuals from March 2002 - August 2003 in ...a longitudinal field population study. There were significant macrohabitat associations with serological status, but selection for most microhabitat variables did not differ between seropositive and seronegative animals. Seropositive adult males moved farther (had larger home ranges) than did seronegatives and were larger in terms of mass and testes size. These patterns may reflect the influence of infection on rodent ecology in terms of dominance and access to preferred habitats.
Durante dos años consecutivos (marzo 2002 a agosto del 2003), estudiamos la ecología básica de Oryzomys palustris, el reservorio natural de la cepa Bayou de Hantavirus, bajo la hipótesis de que el estado serológico afectaba dos variables demográficas: el tamaño del ámbito de hogar (home range) y el uso de hábitat. Encontramos asociaciones significativas entre uso del macrohábitat y el estado serológico, pero no se encontraron diferencias en el uso del microhabitat entre entre animales seropositivos y seronegativos. Sin embargo, machos adultos serológicamente positivos tuvieron ámbitos de hogar más amplios que los seronegativos, además de ser más grandes en términos de masa corporal y tamaño de sus testículos. Sugerimos que estos patrones pueden reflejar la influencia de la infección sobre la ecología de roedores, posiblemente en función de dominancia social y acceso a hábitats preferidos.
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