Learn SwiftUI by designing and building complex user interfaces for watchOS, iPadOS, and iOS with the help of projects including a financial app, a sports news app, and a POS systemKey FeaturesLearn ...SwiftUI with the help of practical cross-platform development projectsUnderstand the design considerations for building apps for different devices such as Apple Watch, iPhone, and iPad using SwiftUI's latest featuresWork with advanced SwiftUI layout features, including SF Symbols, SwiftUI grids, and forms in SwiftUIBook DescriptionReleased by Apple during WWDC 2019, SwiftUI provides an innovative and exceptionally simple way to build user interfaces for all Apple platforms with the power of Swift.This practical guide involves six real-world projects built from scratch, with two projects each for iPhone, iPad, and watchOS, built using Swift programming and Xcode. Starting with the basics of SwiftUI, you'll gradually delve into building these projects. You'll learn the fundamental concepts of SwiftUI by working with views, layouts, and dynamic types. This SwiftUI book will also help you get hands-on with declarative programming for building apps that can run on multiple platforms. Throughout the book, you'll work on a chart app (watchOS), NBA draft app (watchOS), financial app (iPhone), Tesla form app (iPhone), sports news app (iPad), and shoe point-of-sale system (iPad), which will enable you to understand the core elements of a SwiftUI project.By the end of the book, you'll have built fully functional projects for multiple platforms and gained the knowledge required to become a professional SwiftUI developer.What you will learnUnderstand the basics of SwiftUI by building an app with watchOSWork with UI elements such as text, lists, and buttonsCreate a video player in UIKit and import it into SwiftUIDiscover how to leverage an API and parse JSON in your app using CombineStructure your app to use Combine and state-driven featuresCreate flexible layouts on iPadWho this book is forSwiftUI Projects is intended for anyone who is already comfortable with Swift. We do not cover Swift topics in detail, so you need to be familiar with these already. All of the SwiftUI topics are taught as if this is the first time you've learned them and will gradually get more difficult.
iOS 13 Programming for Beginners is a popular introductory guide on learning the essentials of Swift programming and iOS development for building your first iOS app and publishing it on the App ...Store. Fully updated to cover the latest features of iOS 13, you will be up to speed with writing your first iOS app with this practical guide.
Begin your iOS mobile application development journey with this accessible, practical guide About This Book * Use Swift 3 and latest iOS 10 features to build awesome apps for iPhone and iPad * ...Explore and use a wide range of Apple development tools to become a confident iOS developer * From prototype to App Store—find out how to build an app from start to finish! Who This Book Is For This book is for beginners who want to be able to create iOS applications. If you have some programming experience, this book is a great way to get a full understanding of how to create an iOS application from scratch and submit it to the App Store. You do not need any knowledge of Swift or any prior programming experience. What You Will Learn * Get to grips with Swift 3 and Xcode, the building blocks of Apple development * Get to know the fundamentals of Swift, including variables, constants, and control flow * Discover the distinctive design principles that define the iOS user experience * See how to prototype your app with Swift's Playgrounds feature * Build a responsive UI that looks great on a range of devices * Find out how to use CoreLocation to add location services to your app * Add push notifications to your app * Make your app able to be used on both iPhone and iPad In Detail You want to build iOS applications for iPhone and iPad—but where do you start? Forget sifting through tutorials and blog posts, this is a direct route into iOS development, taking you through the basics and showing you how to put the principles into practice. With every update, iOS has become more and more developer-friendly, so take advantage of it and begin building applications that might just take the App Store by storm! Whether you're an experienced programmer or a complete novice, this book guides you through every facet of iOS development. From Xcode and Swift—the building blocks of modern Apple development—and Playgrounds for beginners, one of the most popular features of the iOS development experience, you'll quickly gain a solid foundation to begin venturing deeper into your development journey. For the experienced programmer, jump right in and learn the latest iOS 10 features. You'll also learn the core elements of iOS design, from tables to tab bars, as well as more advanced topics such as gestures and animations that can give your app the edge. Find out how to manage databases, as well as integrating standard elements such as photos, GPS into your app. With further guidance on beta testing with TestFlight, you'll quickly learn everything you need to get your project on the App Store! Style and approach Created for anyone that wants to build their first iOS application, this book offers practical, actionable guidance through iOS development. Combining engaging visuals with accessible, step-by-step instructiona and explanation, this book will not only develop the your understanding, but also show you how to put your knowledge to work.
Begin your iOS mobile application development journey with this accessible, practical guide About This Book. Use Swift 3 and latest iOS 10 features to build awesome apps for iPhone and iPad. Explore ...and use a wide range of Apple development tools to become a confident iOS developer. From prototype to App Store—find out how to build an app from start to finish! Who This Book Is For This book is for beginners who want to be able to create iOS applications. If you have some programming experience, this book is a great way to get a full understanding of how to create an iOS application from scratch and submit it to the App Store. You do not need any knowledge of Swift or any prior programming experience. What You Will Learn. Get to grips with Swift 3 and Xcode, the building blocks of Apple development. Get to know the fundamentals of Swift, including variables, constants, and control flow. Discover the distinctive design principles that define the iOS user experience. See how to prototype your app with Swift's Playgrounds feature. Build a responsive UI that looks great on a range of devices. Find out how to use CoreLocation to add location services to your app. Add push notifications to your app. Make your app able to be used on both iPhone and iPad In Detail You want to build iOS applications for iPhone and iPad—but where do you start? Forget sifting through tutorials and blog posts, this is a direct route into iOS development, taking you through the basics and showing you how to put the principles into practice. With every update, iOS has become more and more developer-friendly, so take advantage of it and begin building applications that might just take the App Store by storm! Whether you're an experienced programmer or a complete novice, this book guides you through every facet of iOS development. From Xcode and Swift—the building blocks of modern Apple development—and Playgrounds for beginners, one of the most popular features of the iOS development experience, you'll quickly gain a solid foundation to begin venturing deeper into your development journey. For the experienced programmer, jump right in and learn the latest iOS 10 features. You'll also learn the core elements of iOS design, from tables to tab bars, as well as more advanced topics such as gestures and animations that can give your app the edge. Find out how to manage databases, as well as integrating standard elements such as photos, GPS into your app. With further guidance on beta testing with TestFlight, you'll quickly learn everything you need to get your project on the App Store! Style and approach Created for anyone that wants to build their first iOS application, this book offers practical, actionable guidance through iOS development. Combining engaging visuals with accessible, step-by-step instructiona and explanation, this book will not only develop the your understanding, but also show you how to put your knowledge to work.
A step-by-step guide to learning iOS app development and exploring the latest Apple development toolsKey FeaturesExplore the latest features of Xcode 11 and the Swift 5 programming language in this ...updated fourth editionKick-start your iOS programming career and have fun building your own iOS appsDiscover the new features of iOS 13 such as Dark Mode, iPad apps for Mac, SwiftUI, and moreBook DescriptioniOS 13 comes with features ranging from Dark Mode and Catalyst through to SwiftUI and Sign In with Apple. If you're a beginner and are looking to experiment and work with these features to create your own apps, then this updated fourth edition gets you off to a strong start. The book offers a comprehensive introduction for programmers who are new to iOS, covering the entire process of learning the Swift language, writing your own apps, and publishing them on the App Store. This edition is updated and revised to cover the new iOS 13 features along with Xcode 11 and Swift 5.
The book starts with an introduction to the Swift programming language, and how to accomplish common programming tasks with it. You'll then start building the user interface (UI) of a complete real-world app, using the latest version of Xcode, and also implement the code for views, view controllers, data managers, and other aspects of mobile apps. The book will then help you apply the latest iOS 13 features to existing apps, along with introducing you to SwiftUI, a new way to design UIs. Finally, the book will take you through setting up testers for your app, and what you need to do to publish your app on the App Store.
By the end of this book, you'll be well versed with how to write and publish apps, and will be able to apply the skills you've gained to enhance your apps.What you will learnGet to grips with the fundamentals of Xcode 11 and Swift 5, the building blocks of iOS developmentUnderstand how to prototype an app using storyboardsDiscover the Model-View-Controller design pattern, and how to implement the desired functionality within the appImplement the latest iOS features such as Dark Mode and Sign In with AppleUnderstand how to convert an existing iPad app into a Mac appDesign, deploy, and test your iOS applications with industry patterns and practicesWho this book is forThis book is for anyone who has programming experience but is completely new to Swift and iOS app development. Experienced programmers looking to explore the latest iOS 13 features will also find this book useful.
Background: The World Meteorological Organization (WMO) has calculated that European temperatures have increased at more than double the global average over the last 30 years 1. Besides research in ...radiation, little research has focused on how this might connect to the mechanisms initiating mutations in ALL. Both latitude and solar irradiance are potential risk factors in the development of ALL 2,3. Latitude covaries with the intensity of solar irradiance and ambient temperature, and both could therefore influence the risk of ALL. Furthermore, high ambient temperature during pregnancy was found to be associated with increased likelihood of childhood ALL 4. Global increases in temperature escalate the likelihood of extreme heat events, which in mammals increases reactive oxygen species, increases DNA damage, and suppresses the immune system 5. Few studies have evaluated changes in ambient temperature as a risk factor for ALL in Europe. We also included chronic lymphocytic leukemia (CLL) for comparison. Objective:To investigate the relationship between population-weighted country centroids (location of greatest population density), average country yearly temperature, solar irradiance and ALL and CLL rates in 40 European countries between the years 2010 and 2019. Design/Method:Incidence and prevalence rates for ALL and CLL (Age-standardized data with males and females) were obtained from the Global Health Data Exchange (GHDx) database. Population-weighted latitude/longitude centroids for Europe 6 were obtained from Baylor University and input into the Global Solar Atlas to obtain the average yearly global horizontal irradiance values. European temperature data was obtained from the Climatic Research Unit at the University of East Anglia (Copernicus Climate Data Store) 7. ALL and CLL incidence and prevalence rates per 100,000 people for 40 European countries were compared by linear regression to each country's temperature or solar irradiance at the population centroids. Statistical analyses were performed using GraphPad Prism and Excel. Results:After2010, we detected a significant positive correlation between ALL incidence and prevalence rates with mean annual temperature across countries for each year of analysis (for example in 2014 the ALL prevalence p-value = 0.01 and R= 0.4, see Figure 1). There was also an increase in the significance of this relationship over time between 2010 and 2019 (Figure 1B). We also detected a significant positive correlation between the increase in mean annual temperature across Europe and an increase in ALL over the past decade (Figure 1B). However, no relationship was established in this study for solar irradiance or population-weighted latitude and CLL prevalence and incidence rates. Conclusions:Increasing mean annual temperatures may increase the risk of developing ALL. We speculate this may be connected through increases in extreme weather events impacting oxidative stress, DNA damage, and/or suppression of the immune system. Considering the global climate crisis, the WMO finding of higher European temperature increases and our finding of significance between temperature and ALL rates, these relationships should be functionally studied. Finally, these studies should be expanded to countries outside of Europe. References 1 World Meteorological Organization. Temperatures in Europe increase more than twice global average. (2022). 2 Pordanjani, S. R., Kavousi, A., Mirbagheri, B., Shahsavani, A. & Etemad, K. Temporal trend and spatial distribution of ALL in Iranian children during 2006-2014: a mixed ecological study. Epidemiol. Health42, (2020). 3 Coste, A. et al. Residential exposure to UV light and risk of precursor B-cell ALL: assessing the role of individual risk factors, the ESCALE and ESTELLE studies. Cancer Causes Control28, 1075-1083 (2017). 4 Rogne, T. et al. High Ambient Temperature in Pregnancy and Risk of Childhood ALL. medRxiv (2023) 5 Chauhan, S. S., Rashamol, V. P., Bagath, M., Sejian, V. & Dunshea, F. R. Impacts of heat stress on immune responses and oxidative stress in farm animals and nutritional strategies for amelioration. Int. J. Biometeorol.65, 1231-1244 (2021). 6 Hamerly, G. Population-weighted European state centers. (2006). 7 Climatic Research Unit, U. of E. A. Temperature and precipitation gridded data for global and regional domains derived from in-situ and satellite observations. (2023).
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Alzheimer's disease (AD), the most common neurodegenerative disorder worldwide, is characterized by increased levels of neurofibrillary tangles and amyloid‐beta plaques. Evidence has ...previously implicated the potent role that insulin resistance plays in the development and progression of AD, suggesting to some that AD represents a distinct type of diabetes. Additionally, disparate lines of evidence find a role for alterations in brain mitochondrial function in AD etiology. We sought to test a unifying hypothesis—namely, that hyperinsulinemia promotes accrual of the sphingolipid ceramide, which, as we've previously found, pathologically alters mitochondrial function. Via daily insulin injections, we induced hyperinsulinemia in ApoE4 mice. In addition to insulin, one group received myriocin injections to inhibit ceramide biosynthesis. We observed significant increases in brain ceramides in the insulin‐treated group, which correlated with disrupted brain mitochondrial function. However, the group receiving myriocin alone, or, importantly, myriocin with insulin had normal lipid profiles and apparently normal mitochondrial bioenergetics. Altogether, our findings suggest a causative role for insulin in AD etiology via an insulin‐induced upregulation of ceramide biosynthesis and accrual in the brain.
According to the Centers for Disease Control (CDC) and Prevention (2013), more than one‐third of U.S. adults (35.7%) are obese, and since 1980, obesity among adolescents has risen from 5% to 18%. To ...prevent obesity the National Heart, Lung and Blood Institute suggests healthy eating. Cooking Anatomy Academy (CAA) teaches anatomy, physiology, and nutrition, and promotes healthy eating and cooking among parents and students in the Polynesian and Pacific Islander communities. CAA is composed of seven, one hour cooking lessons offered as an afterschool program at Mana Academy Charter School (West Valley, UT). The CAA curriculum incorporates nutrition guidelines on MyPlate.gov, and focuses on moderation, variety, and raw/unrefined foods. We studied the impact of CAA using a qualitative analysis of journal entries responding to questions about how participants' experiences in CAA have influenced how they prepare meals at home, and feedback received during the lessons. Preliminary data shows that CAA is helping participants make healthy food choices. Several parents have indicated that their kids are asking to eat healthier foods at home because of the foods they ate in class.
Grant Funding Source: Mentoring Research Grant, College of Life Sciences, Brigham Young University
Innervation to Mandibular Gingiva Dorius, Geoffrey; Fandino, Luis; Sanders, Luke ...
The FASEB journal,
04/2015, Letnik:
29, Številka:
S1
Journal Article
Recenzirano
Odprti dostop
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General sensory innervation of the mandibular gingiva by branches of the mandibular nerve (CN V‐3) is well documented. However, general sensory branches from the lingual nerve that ...traverse the submandibular gland have not been well documented. Therefore, using a combination of macroscopic dissection, MicroScribe 3DX, and Sihler's nerve stain, data was gathered as to which branches of the lingual nerve traverse the submandibular gland on route to innervating the mandibular gingiva. In 30 dissected specimens, the lingual nerve enters the oral cavity near the postero‐lateral surface of the tongue and sends posterior branches into the lingual mandibular gingiva, posterior and medial to the third molars. Other small branches innervate the sublingual gland and the tongue. Anterior nerve branches emerging from the sublingual gland innervate the lingual mandibular gingiva. Altogether, there are an average of 2.62 branches to the mandibular gingiva. The data demonstrated lingual nerve branches that are not presently documented in atlases, and journals. A continuation to collect specimens will allow for a greater amount of information regarding the number of branches from the parent lingual nerve innervating the mandibular gingiva, along with the consistency of how many nervous branches are found. This information could be helpful to dentists in performing local anesthetic blocks.