Functional adaptation and left ventricular dysfunction have been shown by invasive, echocardiographic and radionuclide studies in sickle cell anemia. The studies have documented that abnormal cardiac ...function does occurs in some patients. Magnetic resonance imaging confirms the presence of increased volume and mass, and further indicates that altered function of valves and localized ventricular scars may be found in some cases. Magnetic resonance spectroscopy documents altered metabolism and suggests a potential basis for the altered function is the occurrence of ischemia related to the anemia.< >
Most fMRI studies are conducted with a stimulus 'on' and a stimulus 'off' or control state to delineate pixels activated during a two-condition presentation. The authors have developed a novel ...cross-correlation technique that is not restricted to two conditions and could be applied to delineate pixels activated in multi-condition tasks. A logic-based analysis to form functional images where each pixel shows highest correlation with a specified reference function has also been developed. Using motor stimulation as an example and using right and left hand movements to represent conditions 1 and 2 respectively, and no movement as condition 3, results of images generated through a three-condition processing technique are in good agreement with images generated through two separate two-condition experiments.
Photopenic metastatic lesions on bone scintigraphy have been previously reported. However, this finding is not emphasized for B-cell immunoblastic sarcoma. We report a case of B-cell immunoblastic ...sarcoma, which presented as an aggressive pancoast tumor with extensive rib destruction. Bone scintigraphy findings demonstrated a photopenic lesion with high gallium avidity. Correlative chest radiograph and CT scan are described.
