Population growth, arable land and fresh water limits, and climate change have profound implications for the ability of agriculture to meet this century's demands for food, feed, fiber, and fuel ...while reducing the environmental impact of their production. Success depends on the acceptance and use of contemporary molecular techniques, as well as the increasing development of farming systems that use saline water and integrate nutrient flows.
We present an integrative review of the development of child anxiety, drawing on a number of strands of research. Family aggregation and genetic studies indicate raised vulnerability to anxiety in ...offspring of adults with the disorder (e.g. the temperamental style of behavioural inhibition, or information processing biases). Environmental factors are also important; these include adverse life events and exposure to negative information or modelling. Parents are likely to be key, although not unique, sources of such influences, particularly if they are anxious themselves. Some parenting behaviours associated with child anxiety, such as overprotection, may be elicited by child characteristics, especially in the context of parental anxiety, and these may serve to maintain child disorder. Emerging evidence emphasizes the importance of taking the nature of child and parental anxiety into account, of constructing assessments and interventions that are both disorder specific, and of considering bidirectional influences.
Moisture absorption of natural fiber plastic composites is one major concern in their outdoor applications. Traditionally diffusion theory is applied to understand the mechanism of moisture ...absorption; but it cannot address the relationship between the microscopic structure-infinite 3D-network and the moisture absorption. The purpose of this study is to introduce percolation theory into this field and conduct some preliminary work. First, two new concepts, accessible fiber ratio and diffusion-permeability coefficient, were defined; secondly, a percolation model was developed to estimate the critical accessible fiber ratio; finally, the moisture absorption and electrical conduction behavior of composites with different fiber loadings were investigated. At high fiber loading when accessible fiber ratio is high, the diffusion process is the dominant mechanism; while at low fiber loading close to and below percolation threshold, percolation is the dominant mechanism. The over-estimate of accessible fiber ratio led to discrepancies between the observed and model estimates.
The micromechanical mechanisms that underpin tuning and dynamic range compression in the mammalian inner ear are fundamental to hearing, but poorly understood. Here, we present new, high-resolution ...optical measurements that directly map sound-evoked vibrations on to anatomical structures in the intact, living gerbil cochlea. The largest vibrations occur in a tightly delineated hotspot centering near the interface between the Deiters' and outer hair cells. Hotspot vibrations are less sharply tuned, but more nonlinear, than basilar membrane vibrations, and behave non-monotonically (exhibiting hyper-compression) near their characteristic frequency. Amplitude and phase differences between hotspot and basilar membrane responses depend on both frequency and measurement angle, and indicate that hotspot vibrations involve longitudinal motion. We hypothesize that structural coupling between the Deiters' and outer hair cells funnels sound-evoked motion into the hotspot region, under the control of the outer hair cells, to optimize cochlear tuning and compression.
Abstract
We present the extended GALEX Arecibo SDSS Survey (xGASS), a gas fraction-limited census of the atomic hydrogen (H i) gas content of 1179 galaxies selected only by stellar mass (M⋆ = ...109–1011.5 M⊙) and redshift (0.01 < z < 0.05). This includes new Arecibo observations of 208 galaxies, for which we release catalogues and H i spectra. In addition to extending the GASS H i scaling relations by one decade in stellar mass, we quantify total (atomic+molecular) cold gas fractions and molecular-to-atomic gas mass ratios, Rmol, for the subset of 477 galaxies observed with the IRAM 30 m telescope. We find that atomic gas fractions keep increasing with decreasing stellar mass, with no sign of a plateau down to log M⋆/M⊙ = 9. Total gas reservoirs remain H i-dominated across our full stellar mass range, hence total gas fraction scaling relations closely resemble atomic ones, but with a scatter that strongly correlates with Rmol, especially at fixed specific star formation rate. On average, Rmol weakly increases with stellar mass and stellar surface density μ⋆, but individual values vary by almost two orders of magnitude at fixed M⋆ or μ⋆. We show that, for galaxies on the star-forming sequence, variations of Rmol are mostly driven by changes of the H i reservoirs, with a clear dependence on μ⋆. Establishing if galaxy mass or structure plays the most important role in regulating the cold gas content of galaxies requires an accurate separation of bulge and disc components for the study of gas scaling relations.
We demonstrate the feasibility of probing the charged lepton-flavor-violating decay μ^{+}→e^{+}X^{0} for the presence of a slow-moving neutral boson X^{0} capable of undergoing gravitational binding ...to large structures and, as such, able to participate in some cosmological scenarios. A short exposure to surface antimuons from beam line M20 at TRIUMF generates a branching ratio limit of ≲10^{-5}. This is comparable to or better than previous searches for this channel, although in a thus-far-unexplored region of X^{0} phase space very close to the kinematic limit of the decay, where m_{X^{0}} approaches m_{μ^{+}}. The future improved sensitivity of the method using a customized p-type point-contact germanium detector is described.
H1 linker histones facilitate higher-order chromatin folding and are essential for mammalian development. To achieve high-resolution mapping of H1 variants H1d and H1c in embryonic stem cells (ESCs), ...we have established a knock-in system and shown that the N-terminally tagged H1 proteins are functionally interchangeable to their endogenous counterparts in vivo. H1d and H1c are depleted from GC- and gene-rich regions and active promoters, inversely correlated with H3K4me3, but positively correlated with H3K9me3 and associated with characteristic sequence features. Surprisingly, both H1d and H1c are significantly enriched at major satellites, which display increased nucleosome spacing compared with bulk chromatin. While also depleted at active promoters and enriched at major satellites, overexpressed H1(0) displays differential binding patterns in specific repetitive sequences compared with H1d and H1c. Depletion of H1c, H1d, and H1e causes pericentric chromocenter clustering and de-repression of major satellites. These results integrate the localization of an understudied type of chromatin proteins, namely the H1 variants, into the epigenome map of mouse ESCs, and we identify significant changes at pericentric heterochromatin upon depletion of this epigenetic mark.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
It is argued that event perception and routine sequential action production share a range of characteristics (e.g., similar levels of automaticity, the involvement of sequentially and hierarchically ...organized schemata, and the coupled operation of predictive and monitoring processes). With this in mind, and in an effort to develop a mechanistic account of event perception, we consider how an existing model of routine sequential action production might be applied in the domain of event perception. We focus the discussion on the multiple roles of prediction in the two domains, and we consider the implications of the application of the model of action production to event perception and for sequential processing more generally.
Cooper argues for the use of event representations in action execution, as well as in event perception, and foresees multiple roles for prediction in each case. He argues for strong similarities between perceptual and motor processing of events, and considers how the ‘contention scheduling’ model of action execution could be redeployed for event perception.
The mass of the dark matter halo of the Milky Way can be estimated by fitting analytical models to the phase-space distribution of dynamical tracers. We test this approach using realistic mock ...stellar haloes constructed from the Aquarius N-body simulations of dark matter haloes in the Λ cold dark matter cosmology. We extend the standard treatment to include a Navarro–Frenk–White potential and use a maximum likelihood method to recover the parameters describing the simulated haloes from the positions and velocities of their mock halo stars. We find that the estimate of halo mass is highly correlated with the estimate of halo concentration. The best-fitting halo masses within the virial radius, R
200, are biased, ranging from a 40 per cent underestimate to a 5 per cent overestimate in the best case (when the tangential velocities of the tracers are included). There are several sources of bias. Deviations from dynamical equilibrium can potentially cause significant bias; deviations from spherical symmetry are relatively less important. Fits to stars at different galactocentric radii can give different mass estimates. By contrast, the model gives good constraints on the mass within the half-mass radius of tracers even when restricted to tracers within 60 kpc. The recovered velocity anisotropies of tracers, β, are biased systematically, but this does not affect other parameters if tangential velocity data are used as constraints.