We present the results of a transcontinental campaign to observe the 2009 June 5 transit of the exoplanet HD 80606b. We report the first detection of the transit ingress, revealing the transit ...duration to be 11.64 +/- 0.25 hr and allowing more robust determinations of the system parameters. Keck spectra obtained at midtransit exhibit an anomalous blueshift, giving definitive evidence that the stellar spin axis and planetary orbital axis are misaligned. The Keck data show that the projected spin-orbit angle is between 32-87 deg with 68.3% confidence and between 14-142 deg with 99.73% confidence. Thus the orbit of this planet is not only highly eccentric (e=0.93), but is also tilted away from the equatorial plane of its parent star. A large tilt had been predicted, based on the idea that the planet's eccentric orbit was caused by the Kozai mechanism. Independently of the theory, it is noteworthy that all 3 exoplanetary systems with known spin-orbit misalignments have massive planets on eccentric orbits, suggesting that those systems migrate differently than lower-mass planets on circular orbits.
Open clusters have been the focus of several exoplanet surveys, but only a few planets have so far been discovered. The Kepler spacecraft revealed an abundance of small planets around small cool ...stars, therefore, such cluster members are prime targets for exoplanet transit searches. Kepler's new mission, K2, is targeting several open clusters and star-forming regions around the ecliptic to search for transiting planets around their low-mass constituents. Here, we report the discovery of the first transiting planet in the intermediate-age (800 Myr) Beehive cluster (Praesepe). K2-95 is a faint (Kp = 15.5 mag) M3.0 +/- 0.5 dwarf from K2's Campaign 5 with an effective temperature of 3471 +/- 124 K, approximately solar metallicity and a radius of 0.402 +/- 0.050 R-circle dot. We detected a transiting planet with a radius of 3.47(-0.53)(+0.78)R(circle plus) and an orbital period of 10.134 days. We combined photometry, medium/high-resolution spectroscopy, adaptive optics/speckle imaging, and archival survey images to rule out any false-positive detection scenarios, validate the planet, and further characterize the system. The planet's radius is very unusual as M-dwarf field stars rarely have Neptune-sized transiting planets. The comparatively large radius of K2-95b is consistent with the other recently discovered cluster planets K2-25b (Hyades) and K2-33b (Upper Scorpius), indicating systematic differences in their evolutionary states or formation. These discoveries from K2 provide a snapshot of planet formation and evolution in cluster environments and thus make excellent laboratories to test differences between field-star and cluster planet populations.
We present a catalog of 11 multiplanet systems from Campaigns 1 and 2 of the K2 mission. We report the sizes and orbits of 26 planets split between seven two-planet systems and four three-planet ...systems. These planets stem from a systematic search of the K2 photometry for all dwarf stars observed by K2 in these fields. We precisely characterized the host stars with adaptive optics imaging and analysis of high-resolution optical spectra from Keck/HIRES and medium-resolution spectra from IRTF/SpeX. We confirm two planet candidates by mass detection and validate the remaining 24 candidates to >99% confidence. Thirteen planets were previously validated or confirmed by other studies, and 24 were previously identified as planet candidates. The planets are mostly smaller than Neptune (21/26 planets), as in the Kepler mission, and all have short periods (P < 50 days) due to the duration of the K2 photometry. The host stars are relatively bright (most have Kp < 12.5 mag) and are amenable to follow-up characterization. For K2-38, we measured precise radial velocities using Keck/HIRES and provide initial estimates of the planet masses. K2-38b is a short-period super-Earth with a radius of 1.55 +/- 0.16 R-circle plus, a mass of 12.0 +/- 2.9M(circle plus), and a high density consistent with an iron-rich composition. The outer planet K2-38c is a lower-density sub-Neptune-size planet with a radius of 2.42 +/- 0.29 R-circle plus and a mass of 9.9 +/- 4.6M(circle plus) that likely has a substantial envelope. This new planet sample demonstrates the capability of K2 to discover numerous planetary systems around bright stars.
We present 197 planet candidates discovered using data from the first year of the NASA K2 mission (Campaigns 0-4), along with the results of an intensive program of photometric analyses, stellar ...spectroscopy, high-resolution imaging, and statistical validation. We distill these candidates into sets of 104 validated planets (57 in multi-planet systems), 30 false positives, and 63 remaining candidates. Our validated systems span a range of properties, with median values of R-P = 2.3 R-circle plus, P = 8.6 days, T-eff = 5300 K, and Kp = 12.7 mag. Stellar spectroscopy provides precise stellar and planetary parameters for most of these systems. We show that K2 has increased by 30% the number of small planets known to orbit moderately bright stars (1-4 R-circle plus, Kp = 9-13. mag). Of particular interest are 76 planets smaller than 2 R-circle plus, 15 orbiting stars brighter than Kp = 11.5. mag, 5 receiving Earth-like irradiation levels, and several multi-planet systems-including 4 planets orbiting the M dwarf K2-72 near mean-motion resonances. By quantifying the likelihood that each candidate is a planet we demonstrate that our candidate sample has an overall false positive rate of 15%-30%, with rates substantially lower for small candidates (<2 R-circle plus) and larger for candidates with radii >8 R-circle plus and/or with P < 3 days. Extrapolation of the current planetary yield suggests that K2 will discover between 500 and 1000 planets in its planned four-year mission, assuming sufficient follow-up resources are available. Efficient observing and analysis, together with an organized and coherent follow-up strategy, are essential for maximizing the efficacy of planet-validation efforts for K2, TESS, and future large-scale surveys.
HD 3167 is a bright (V = 8.9), nearby KO star observed by the NASA K2 mission (EPIC 220383386), hosting two small, short-period transiting planets. Here we present the results of a multi-site, ...multi-instrument radial-velocity campaign to characterize the HD 3167 system. The masses of the transiting planets are 5.02 +/- 0.38 M-circle plus for HD 3167 b, a hot super-Earth with a likely rocky composition (rho(b) = 5.6(-1.43)(+2.15) g cm(-3)), and 9.80(-1.24)(+1.30) M-circle plus for HD 3167 c, a warm sub-Neptune with a likely substantial volatile complement (rho(c) = 1.97(-0.59)(+0.94) g cm(-3)). We explore the possibility of atmospheric composition analysis and determine that planet c is amenable to transmission spectroscopy measurements, and planet b is a potential thermal emission target. We detect a third, non-transiting planet, HD 3167 d, with a period of 8.509 +/- 0.045 d (between planets b and c) and a minimum mass of 6.90 +/- 0.71 M-circle plus. We are able to constrain the mutual inclination of planet d with planets b and c: we rule out mutual inclinations below 1.degrees 3 because we do not observe transits of planet d. From 1.degrees 3 to 40 degrees, there are viewing geometries invoking special nodal configurations, which result in planet d not transiting some fraction of the time.
Objective
To characterize the immune cells present in different forms of feline anterior uveitis.
Samples
Eyes were obtained from 49 cats diagnosed with chronic idiopathic lymphoplasmacytic anterior ...uveitis, 7 cats with feline infectious peritonitis (FIP), and 9 cats euthanized for nonocular disease.
Methods
H&E sections were scored on the level of infiltrate in the anterior uvea. Immunohistochemistry was performed for FoxP3, CD3, and IL‐17A, and positive cells were quantified in multiple images of each sample. A generalized estimating equation tested for an association between the level of inflammation and the prevalence of these cell types.
Results
Cells stained positive for IL‐17A in idiopathic uveitis but not in FIP samples. We found significantly fewer FoxP3+ and CD3+ cells in low‐grade compared with high‐grade inflammation in idiopathic uveitis or FIP samples (P values all <.005), but no difference between FIP and high‐grade samples.
Conclusions
Idiopathic, but not FIP‐associated, uveitis appears to have Th17 cell involvement. The numbers of FoxP3+ and CD3+ T‐cells present appear directly correlated; thus, the severity of disease does not appear directly determined by the numbers of regulatory cells.
Purpose - Business innovation comes from combining, recombining and modifying existing ideas, knowledge and know-how in new ways. The purpose of this paper is to describe an approach to accelerating ...the business innovation process by priming the combining and recombining process, called the Business Genome Project (BGP).Design methodology approach - Business innovation and evolution is compared to cultural and biological evolution and the Human Genome Project (HGP) is used as a template for developing the business genome concept, which involves identifying and mapping the building blocks of extant businesses.Findings - The paper describes a way of priming the innovation pump by aiding the identification and sharing of key business ideas, knowledge and know-how across firms, organisations, industries, technologies and nations. Recent developments in internet-based technologies, like Wikipedia and the Encyclopedia of Life, suggest the project is feasible.Practical implications - The BGP can provide a fundamental, new understanding of the commercial world: its businesses, their know-how, their context and their cultures. It also provides a basis for on-going collaboration, communication, research and development, amongst businesses (and their stakeholders), which would accelerate the innovation process.Originality value - The BGP is an original idea inspired by the HGP that promises to have a similar impact on business practice, policy and research.
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