Abstract Tic disorders constitute a neurodevelopmental disorder of childhood. This study sought to determine the prevalence of tic disorders in a school-based sample. A randomized sample of 1158 ...schoolchildren, based on clusters (classrooms) in the province of Burgos (Spain), was identified on a stratified sampling frame combining types of educational center and setting (mainstream schools and special education), using a two-phase approach (screening and diagnosis ascertainment by a neurologist). Tics with/without impairment criterion were diagnosed according to Diagnostic and Statistical Manual of Mental Disorders criteria. In mainstream schools, tics were observed in 125/741 students (16.86%; 95% confidence interval, 14.10-19.63), and were more frequent in boys (87/448, 19.42%; 95% confidence interval, 15.64-23.19) compared with girls (38/293, 12.96%; 95% confidence interval, 8.95-16.98; P = 0.03). In special education centers, tics disorders were observed in 11/54 of children (20.37%; 95% confidence interval, 8.70-32.03). Overall, tics with impairment criteria were less frequent than tics without impairment criteria (4.65% vs 11.85%, P < 0.0001). The most frequent diagnoses involved chronic motor tics (6.07%) and Tourette syndrome (5.26%). Tic disorders are common in childhood, and the use or nonuse of impairment criteria exerts a significant impact on tic prevalence estimates.
Restless legs syndrome (RLS) is a common sleep disorder,. although controversial, growing evidence relates the presence of RLS to an increased risk of mortality, mainly due to cardiovascular events. ...The aim of this article was to review the role of RLS as a risk factor of mortality according to independent cohort studies.BackgroundRestless legs syndrome (RLS) is a common sleep disorder,. although controversial, growing evidence relates the presence of RLS to an increased risk of mortality, mainly due to cardiovascular events. The aim of this article was to review the role of RLS as a risk factor of mortality according to independent cohort studies.We performed a literature review via PubMed database for articles relating RLS and mortality. We used the random-effects model to calculate the pooled effect estimates on mortality. Heterogeneity between studies was assessed using quantitative and qualitative analysis.MethodsWe performed a literature review via PubMed database for articles relating RLS and mortality. We used the random-effects model to calculate the pooled effect estimates on mortality. Heterogeneity between studies was assessed using quantitative and qualitative analysis.Out of 100 articles identified, 13 were finally included. Although studies were heterogeneous (p = 0.001), no significant publication bias was found. When all cohort studies were considered, the random-effects model yielded a significantly increased risk of mortality in RLS versus non-RLS patients (13 studies, hazard ratio HR = 1.52, 95% confidence interval CI 1.28-1.80). However, this association was not statistically significant when only cohort studies using the international RLS diagnostic criteria were considered (5 studies, HR = 1.63, 95% CI 0.94-2.81).ResultsOut of 100 articles identified, 13 were finally included. Although studies were heterogeneous (p = 0.001), no significant publication bias was found. When all cohort studies were considered, the random-effects model yielded a significantly increased risk of mortality in RLS versus non-RLS patients (13 studies, hazard ratio HR = 1.52, 95% confidence interval CI 1.28-1.80). However, this association was not statistically significant when only cohort studies using the international RLS diagnostic criteria were considered (5 studies, HR = 1.63, 95% CI 0.94-2.81).The results of this meta-analysis suggest that RLS seems to be a risk factor of mortality, although this association is conditioned by the diagnostic criteria used in the studies. Future long-term follow-up standardized mortality studies are needed to address this important question that carries potential impact on population global health.DiscussionThe results of this meta-analysis suggest that RLS seems to be a risk factor of mortality, although this association is conditioned by the diagnostic criteria used in the studies. Future long-term follow-up standardized mortality studies are needed to address this important question that carries potential impact on population global health.
Author Response to Letter to the Editor Castrillo-Fraile, Victoria; Peña, Elena Casas; Galán, José María Trejo Gabriel Y ...
Tremor and other hyperkinetic movements (New York, N.Y.),
2020, Letnik:
10
Journal Article
Inspiratory Myoclonus Dekker, Marieke C J; Kilonzo, Kajiru G; Howlett, William P ...
Tremor and other hyperkinetic movements (New York, N.Y.),
02/2019, Letnik:
9
Journal Article
Recenzirano
Odprti dostop
BackgroundMovement disorders of respiration are rare and are restricted to a phase of the respiratory cycle. Phenomenology ShownThe intermittent inspiratory myoclonus in this patient with post-anoxic ...encephalopathy is likely to be of brainstem origin. Educational ValueRare movement disorders can be identified even in remote areas of the world where access to neurological care is limited.
En esta contribución se presenta el trabajo realizado dentro del proyecto Europeo Erasmus+ FORDYSVAR, cuyo objetivo principal es contribuir a la inclusión educativa de los estudiantes con dislexia, ...en edades comprendidas entre los 10 y los 16 años, mediante el uso de tecnologías emergentes, concretamente la Realidad Virtual (RV) y la Realidad Aumentada (RA) para mejorar el acceso, la participación y los logros educativos de los estudiantes con esta dificultad de aprendizaje. El propósito es generar un entorno de aprendizaje lúdico, divertido y seguro consiguiendo de esta manera un mayor compromiso hacia el tratamiento y mejorando su calidad de vida. Entre los resultados derivados de este proyecto se encuentra el diseño y creación de una aplicación de RV y RA que contribuya al aprendizaje de estudiantes con dislexia a partir del Diseño Centrado en el Usuario como metodología. Los resultados obtenidos hasta el momento permiten concluir que las tecnologías emergentes (RV y RA), son una interesante vía de tratamiento ya que ofrecen un entorno lúdico, seguro, controlado y motivador para los estudiantes con dislexia.
BACKGROUNDX-linked spinal and bulbar muscular atrophy (SBMA) is a rare adult-onset neuronopathy. Although tremor is known to occur in this disease, the number of reported cases of SBMA with tremor is ...rare, and the number with videotaped documentation is exceedingly rare. Our aim was to describe/document the characteristic signs of tremor in spinal and bulbar muscular atrophy. CASE REPORTWe report a case of a 58-year-old male with a positive family history of tremor. On examination, the patient had jaw and hand tremors but he also exhibited gynecomastia, progressive bulbar paresis, and wasting and weakness primarily in the proximal limb muscles. The laboratory tests revealed an elevated creatine phosphokinase. Genetic testing was positive for X-SBMA, with 42 CAG repeats. DISCUSSIONEssential tremor is one of the most common movement disorders, yet it is important for clinicians to be aware of the presence of other distinguishing features that point to alternative diagnoses. The presence of action tremor associated with muscle atrophy and gynecomastia should lead to a suspicion of SBMA.
PDF