The overall increase of chronic degenerative diseases associated with ageing makes wound care a tremendous socioeconomic burden. Thus, there is a growing need to develop novel wound healing therapies ...to improve cutaneous wound healing. The use of regenerative therapies is becoming increasingly popular due to the low-invasive procedures needed to apply them. Platelet-rich plasma (PRP) is gaining interest due to its potential to stimulate and accelerate the wound healing process. The cytokines and growth factors forming PRP play a crucial role in the healing process. This article reviews the emerging field of skin wound regenerative therapies with particular emphasis on PRP and the role of growth factors in the wound healing process.
Articular cartilage injuries are a severe problem, and the treatments for these injuries are complex. The present study investigates a treatment for full-thickness cartilage defects called Autologous ...Chondral Platelet Rich Plasma Matrix Implantation (PACI) in a sheep model.
Chondral defects 8 mm in diameter were surgically induced in the medial femoral condyles of both stifles in eight healthy sheep. Right stifles were treated with PACI and an intraarticular injection with a plasma rich in growth factors (PRGF) solution treatment group (TRT), while an intraarticular injection of Ringer's lactate solution was administered in left stifles Control group (CT). The limbs' function was objectively assessed with a force platform to obtain the symmetry index, comparing both groups. After 9 and 18 months, the lesions were macroscopically evaluated using the International Cartilage Repair Society and Goebel scales.
Regarding the symmetry index, the TRT group obtained results similar to those of healthy limbs at 9 and 18 months after treatment. Regarding the macroscopic assessment, the values obtained by the TRT group were very close to those of normal cartilage and superior to those obtained by the CT group at 9 months.
This new bioregenerative treatment modality can regenerate hyaline articular cartilage. High functional outcomes have been reported, together with a good quality repair tissue in sheep. Therefore, PACI treatment might be a good therapeutic option for full-thickness chondral lesions.
Cooperative Learning in Veterinary Science Alcántara, Déborah Chicharro; Sopena-Juncosa, Joaquin Jesus; Damiá-Giménez, Elena ...
JOURNAL OF ADVANCES IN AGRICULTURE,
08/2018, Letnik:
8
Journal Article
Cooperative learning is an instructional method based on teamwork, by reinforcing a student´s own learning as well as the learning of his or her fellow members. Thus, this kind of cooperative model ...achieves personal and team success at the same time. With this aim, an experience was designed where students from veterinary surgery and propaedeutics from the Universities of Las Palmas de Gran Canaria (ULPGC) and CEU Cardenal Herrera of Valencia (UCH-CEU) simultaneously performed surgical practices in the Veterinary Medicine Degree. Propaedeutic students were evaluated previously and after the practical period with surgery multiple-choice questions and results were compared. The obtained results allow us to conclude that students after interaction gained advanced knowledge in veterinary surgery.