We present cosmological results from a combined analysis of galaxy clustering and weak gravitational lensing, using 1321 deg2 of griz imaging data from the first year of the Dark Energy Survey (DES ...Y1). We combine three two-point functions: (i) the cosmic shear correlation function of 26 million source galaxies in four redshift bins, (ii) the galaxy angular autocorrelation function of 650,000 luminous red galaxies in five redshift bins, and (iii) the galaxy-shear cross-correlation of luminous red galaxy positions and source galaxy shears. To demonstrate the robustness of these results, we use independent pairs of galaxy shape, photometric-redshift estimation and validation, and likelihood analysis pipelines. To prevent confirmation bias, the bulk of the analysis was carried out while “blind” to the true results; we describe an extensive suite of systematics checks performed and passed during this blinded phase. The data are modeled in flat ΛCDM and wCDM cosmologies, marginalizing over 20 nuisance parameters, varying 6 (for ΛCDM) or 7 (for wCDM) cosmological parameters including the neutrino mass density and including the 457×457 element analytic covariance matrix. We find consistent cosmological results from these three two-point functions and from their combination obtain S8≡σ8(Ωm/0.3)0.5=0.773−0.020+0.026 and Ωm=0.267−0.017+0.030 for ΛCDM; for wCDM, we find S8=0.782−0.024+0.036, Ωm=0.284−0.030+0.033, and w=−0.82−0.20+0.21 at 68% C.L. The precision of these DES Y1 constraints rivals that from the Planck cosmic microwave background measurements, allowing a comparison of structure in the very early and late Universe on equal terms. Although the DES Y1 best-fit values for S8 and Ωm are lower than the central values from Planck for both ΛCDM and wCDM, the Bayes factor indicates that the DES Y1 and Planck data sets are consistent with each other in the context of ΛCDM. Combining DES Y1 with Planck, baryonic acoustic oscillation measurements from SDSS, 6dF, and BOSS and type Ia supernovae from the Joint Lightcurve Analysis data set, we derive very tight constraints on cosmological parameters: S8=0.802±0.012 and Ωm=0.298±0.007 in ΛCDM and w=−1.00−0.04+0.05 in wCDM. Upcoming Dark Energy Survey analyses will provide more stringent tests of the ΛCDM model and extensions such as a time-varying equation of state of dark energy or modified gravity.
Swietenia macrophylla King is a plant commonly known as Brazilian mahogany. The wood from its stem is highly prized for its exceptional quality, while its leaves are valued for their high content of ...phragmalin-type limonoids, a subclass of compounds known for their significant biological activities, including antimalarial, antitumor, antiviral, and anti-inflammatory properties. In this context, twelve isolated limonoids from S. macrophylla leaves were employed as standards in mass spectrometry-based molecular networking to unveil new potential mass spectrometry signatures for phragmalin-type limonoids. Consequently, ultra-performance liquid chromatography coupled with high-resolution mass spectrometry was utilized for data acquisition. Subsequently, the obtained data were analyzed using the Global Natural Products Social Molecular Networking platform based on spectral similarity. In summary, this study identified 24 new putative phragmalin-type limonoids for the first time in S. macrophylla. These compounds may prove valuable in guiding future drug development efforts, leveraging the already established biological activities associated with limonoids.
Migration from rural areas of India contributes to urbanisation and may increase the risk of obesity and diabetes. We tested the hypotheses that rural-to-urban migrants have a higher prevalence of ...obesity and diabetes than rural nonmigrants, that migrants would have an intermediate prevalence of obesity and diabetes compared with life-long urban and rural dwellers, and that longer time since migration would be associated with a higher prevalence of obesity and of diabetes.
The place of origin of people working in factories in north, central, and south India was identified. Migrants of rural origin, their rural dwelling sibs, and those of urban origin together with their urban dwelling sibs were assessed by interview, examination, and fasting blood samples. Obesity, diabetes, and other cardiovascular risk factors were compared. A total of 6,510 participants (42% women) were recruited. Among urban, migrant, and rural men the age- and factory-adjusted percentages classified as obese (body mass index BMI >25 kg/m(2)) were 41.9% (95% confidence interval CI 39.1-44.7), 37.8% (95% CI 35.0-40.6), and 19.0% (95% CI 17.0-21.0), respectively, and as diabetic were 13.5% (95% CI 11.6-15.4), 14.3% (95% CI 12.2-16.4), and 6.2% (95% CI 5.0-7.4), respectively. Findings for women showed similar patterns. Rural men had lower blood pressure, lipids, and fasting blood glucose than urban and migrant men, whereas no differences were seen in women. Among migrant men, but not women, there was weak evidence for a lower prevalence of both diabetes and obesity among more recent (</=10 y) migrants.
Migration into urban areas is associated with increases in obesity, which drive other risk factor changes. Migrants have adopted modes of life that put them at similar risk to the urban population. Gender differences in some risk factors by place of origin are unexpected and require further exploration. Please see later in the article for the Editors' Summary.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
The super-weak interaction includes three simple extensions of the standard model: gauge extension, fermionic extension, and scalar extension. All of these extensions are strongly influenced by their ...complex phenomenology. They can explain a number of unresolved questions in particle physics and cosmology, including the genesis of dark matter, cosmic inflation, asymmetry of matter and antimatter, neutrino masses, and vacuum stability, if combined into a single structure. This is an extension of the gauge group of the standard model
by
without any anomalies. We investigate the implications of the development of a general Majorana mass renormalization group for neutrinos with masses in the range of 0.03 and 0.1 eV, which fall within the recently published range as well as the range to be explored in future planned experiments.
Enhancing the proactive strategic capabilities to withstand the most unfavourable circumstances is always appreciated as a long-term policy rather than incident-based responses. The present research ...is positioned on this fundamental notion of supply chain risk management with a particular focus on strategic capabilities like reliability and flexibility that often conflict with cost. Accordingly, the authors propose a multi-objective mathematical model for designing a four-echelon supply chain that optimises cost, reliability, and volume flexibility. Interestingly, this research is the maiden effort to optimise the supply chain with these trifold objectives and herein lies the novelty as well as the challenges. Consequently, a genetic algorithm based approach is utilised as the solution methodology. To demonstrate the effectiveness of the proposed method, the small problem instances and the four-echelon problems have also been validated through exact methods and simulated annealing algorithm, respectively. A case study on a footwear supply chain involving three echelons is also presented to showcase the industrial applicability and adaptability of the proposed model. A fuzzy TOPSIS method has been adopted in the case study to incorporate the expert opinion for assigning priorities to the objectives. Supply chain professionals can leverage this methodology to establish a risk resistant supply chain.
We analyze transient finite electroelastodynamic deformations of a perfect electrically conducting undamped clamped-clamped beam, a clamped-clamped parabolic arch and a clamped-clamped bell-shaped ...arch suspended over a flat rigid semi-infinite perfect conductor. The pull-in instability in a beam and the pull-in and the snap-through instabilities in the two arches due to time-dependent potential difference between the two electrodes have been studied. The potential difference is applied either suddenly or is increased linearly in time. Since the time scale of the transient electric forces is very small as compared to that of the mechanical forces, inertia effects only in the mechanical deformations are considered. Effects of both material and geometric nonlinearities are incorporated in the problem formulation and solution; however, damping due to the interaction of the structure with the surrounding medium is neglected. The coupled nonlinear partial differential equations for mechanical deformations are solved numerically by the finite element method and those for the electrical problem by the boundary element method. The Coulomb pressure due to the potential difference between the two electrodes is a nonlinear function of the a priori unknown distance between them. The potential difference that induces either the pull-in instability in a beam or the snap-through followed by the pull-in instabilities in an arch has been computed. Wherever possible these results are compared with those available in the literature. With a decrease in the rate of the applied potential difference, the pull-in and the snap-through parameters approach those for a static problem. Also, for large rates of increase in the potential difference between the two electrodes, the snap-through instability in an arch is suppressed and only the pull-in instability occurs.
Interior Antarctica is among the most remote places on Earth and was thought to be beyond the reach of human impacts when Amundsen and Scott raced to the South Pole in 1911. Here we show detailed ...measurements from an extensive array of 16 ice cores quantifying substantial toxic heavy metal lead pollution at South Pole and throughout Antarctica by 1889 - beating polar explorers by more than 22 years. Unlike the Arctic where lead pollution peaked in the 1970s, lead pollution in Antarctica was as high in the early 20(th) century as at any time since industrialization. The similar timing and magnitude of changes in lead deposition across Antarctica, as well as the characteristic isotopic signature of Broken Hill lead found throughout the continent, suggest that this single emission source in southern Australia was responsible for the introduction of lead pollution into Antarctica at the end of the 19(th) century and remains a significant source today. An estimated 660 t of industrial lead have been deposited over Antarctica during the past 130 years as a result of mid-latitude industrial emissions, with regional-to-global scale circulation likely modulating aerosol concentrations. Despite abatement efforts, significant lead pollution in Antarctica persists into the 21(st) century.
Arch-shaped microelectromechanical systems (MEMS) have been used as mechanical memories, micro-relays, micro-valves, optical switches and digital micro-mirrors. A bi-stable structure, such as an ...arch, is characterized by a multivalued load deflection curve. Here we study the symmetry breaking, the snap-through instability and the pull-in instability of a bi-stable arch-shaped MEMS under static and dynamic electric loads. Unlike a mechanical load, the electric load is a nonlinear function of the a priori unknown deformed shape of the arch. The nonlinear partial differential equation governing transient deformations of the arch is solved numerically using the Galerkin method and a time integration scheme that adaptively adjusts the time step to compute the solution within the prescribed tolerance. For the static problem, the displacement control and the pseudo-arc-length continuation methods are used to obtain the bifurcation curve of the arch's displacement versus a load parameter. The displacement control method fails to compute the arch's asymmetric deformations that are found by the pseudo-arc-length continuation method. For the dynamic problem, two distinct mechanisms of the snap-through instability are found. It is shown that critical loads and geometric parameters for instabilities of an arch under an electric load with and without consideration of mechanical inertia effects are quite different. A phase diagram between a critical load parameter and the arch height is constructed to delineate different regions of instabilities. We compare results from the present model with those from a continuum mechanics based approach, and with results of other models and experiments available in the literature.
Interaction with electron-donor and -acceptor molecules such as aniline and nitrobenzene brings about marked changes in the D, G, G' and 2D bands of the Raman spectrum and the electronic structure of ...graphene, prepared by the exfoliation of graphitic oxide.
Type 304 stainless steel is a metastable austenitic stainless steel that undergoes strain induced transformation from austenite to α′ martensite during deformation at room temperature. Role of prior ...deformation, by rolling at room temperature and at 200 °C (a temperature at which the strain induced martensitic transformation does not occur), on the subsequent room temperature tensile deformation behaviour of the austenite phase is investigated. The changes in dislocation density of the parent phase and the volume fraction of the martensite formed due to deformation were estimated by X-ray diffraction line profile analysis of data obtained from Beam Line - 12 of the Indus 2 synchrotron. The contrast caused by dislocations in the austenite phase has been addressed using the modified Williamson-Hall method. The character of dislocations changes from screw to edge above a critical equivalent strain of ~0.14. The influence of martensite formation on the increase in dislocation density in the austenite phase is confirmed from XRDLPA. An alternative approach to determine dislocation density is proposed which is independent of elastic constants of the material and is found to correlate well with the values determined by the Williamson-Smallman approach. The results obtained from XRDLPA are corroborated with EBSD analysis. It is also seen that the composite strength of the steel, which has undergone different levels of deformation, is related to the changes in dislocation density of austenite and volume fraction of martensite based on Taylor's equation enabling correlation of structure-property.
•Deformation induced change in dislocation density (ρ) and character are studied by XRDLPA.•Strengthening due to α′ martensite and ρ in austenite are related through rule of mixtures.•SIM contributes to strengthening by introducing extra dislocations into γ phase.•Results from EBSD analysis corroborate the findings of XRDLPA.•Alternative approach to determine ρ from different forms of mWH equation is proposed.
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