We report high-quality, H or CO rotation curves (RCs) to several Re for 41 large, massive, star-forming disk galaxies (SFGs) across the peak of cosmic galaxy evolution (z ∼ 0.67-2.45), taken with the ...ESO-VLT, the LBT and IRAM-NOEMA. Most RC41 SFGs have reflection-symmetric RCs plausibly described by equilibrium dynamics. We fit the major axis position-velocity cuts using beam-convolved forward modeling generated in three dimensions, with models that include a bulge and turbulent disk component embedded in a dark matter (DM) halo. We include priors for stellar and molecular gas masses, optical light effective radii and inclinations, and DM masses from abundance-matching scaling relations. Two-thirds or more of the z ≥ 1.2 SFGs are baryon dominated within a few Re of typically 5.5 kpc and have DM fractions less than maximal disks (median 〈 f DM ( R e ) 〉 = 0.12 ). At lower redshift (z < 1.2), that fraction is less than one-third. DM fractions correlate inversely with the baryonic angular momentum parameter, baryonic surface density, and bulge mass. Inferred low DM fractions cannot apply to the entire disk and halo but more plausibly reflect a flattened, or cored, inner DM density distribution. The typical central "DM deficit" in these cores relative to Navarro-Frenk-White (NFW) distributions is ∼30% of the bulge mass. The observations are consistent with rapid radial transport of baryons in the first-generation massive gas-rich halos forming globally gravitationally unstable disks and leading to efficient build-up of massive bulges and central black holes. A combination of heating due to dynamical friction and AGN feedback may drive DM out of the initial cusps.
Abstract
We investigate the relationship between star formation activity and outflow properties on kiloparsec scales in a sample of 28 star-forming galaxies at
z
∼ 2–2.6, using adaptive optics ...assisted integral field observations from SINFONI on the Very Large Telescope. The narrow and broad components of the H
α
emission are used to simultaneously determine the local star formation rate surface density (
), and the outflow velocity
and mass outflow rate
, respectively. We find clear evidence for faster outflows with larger mass loading factors at higher
. The outflow velocities scale as
∝
0.34±0.10
, which suggests that the outflows may be driven by a combination of mechanical energy released by supernova explosions and stellar winds, as well as radiation pressure acting on dust grains. The majority of the outflowing material does not have sufficient velocity to escape from the galaxy halos, but will likely be re-accreted and contribute to the chemical enrichment of the galaxies. In the highest
regions the outflow component contains an average of ∼45% of the H
α
flux, while in the lower
regions only ∼10% of the H
α
flux is associated with outflows. The mass loading factor,
η
=
/SFR, is positively correlated with
but is relatively low even at the highest
:
η
≲ 0.5 × (380 cm
−3
/
n
e
). This may be in tension with the
η
≳ 1 required by cosmological simulations, unless a significant fraction of the outflowing mass is in other gas phases and has sufficient velocity to escape the galaxy halos.
ABSTRACT
We report on our combined analysis of HST, VLT/MUSE, VLT/SINFONI, and ALMA observations of the local Seyfert 2 galaxy, NGC 5728 to investigate in detail the feeding and feedback of the ...active galactic nucleus (AGN). The data sets simultaneously probe the morphology, excitation, and kinematics of the stars, ionized gas, and molecular gas over a large range of spatial scales (10 pc to 10 kpc). NGC 5728 contains a large stellar bar that is driving gas along prominent dust lanes to the inner 1 kpc where the gas settles into a circumnuclear ring. The ring is strongly star forming and contains a substantial population of young stars as indicated by the lowered stellar velocity dispersion and gas excitation consistent with H ii regions. We model the kinematics of the ring using the velocity field of the CO (2–1) emission and stars and find it is consistent with a rotating disc. The outer regions of the disc, where the dust lanes meet the ring, show signatures of inflow at a rate of 1 M$\odot$ yr−1. Inside the ring, we observe three molecular gas components corresponding to the circular rotation of the outer ring, a warped disc, and the nuclear stellar bar. The AGN is driving an ionized gas outflow that reaches a radius of 250 pc with a mass outflow rate of 0.08 M$\odot$ yr−1 consistent with its luminosity and scaling relations from previous studies. While we observe distinct holes in CO emission which could be signs of molecular gas removal, we find that largely the AGN is not disrupting the structure of the circumnuclear region.
We present a census of ionized gas outflows in 599 normal galaxies at redshift 0.6 < z < 2.7, mostly based on integral field spectroscopy of Hα, N ii, and S ii line emission. The sample fairly ...homogeneously covers the main sequence of star-forming galaxies with masses 9.0 < log(M */M ⊙) < 11.7, and probes into the regimes of quiescent galaxies and starburst outliers. About one-third exhibits the high-velocity component indicative of outflows, roughly equally split into winds driven by star formation (SF) and active galactic nuclei (AGNs). The incidence of SF-driven winds correlates mainly with SF properties. These outflows have typical velocities of ∼450 km s−1, local electron densities of n e ∼ 380 cm−3, modest mass loading factors of ∼0.1–0.2 at all galaxy masses, and energetics compatible with momentum driving by young stellar populations. The SF-driven winds may escape from log(M */M ⊙) ≲ 10.3 galaxies, but substantial mass, momentum, and energy in hotter and colder outflow phases seem required to account for low galaxy formation efficiencies in the low-mass regime. Faster AGN-driven outflows (∼1000–2000 km s−1) are commonly detected above log(M */M ⊙) ∼ 10.7, in up to ∼75% of log(M */M ⊙) ≳ 11.2 galaxies. The incidence, strength, and velocity of AGN-driven winds strongly correlates with stellar mass and central concentration. Their outflowing ionized gas appears denser (n e ∼ 1000 cm−3), and possibly compressed and shock-excited. These winds have comparable mass loading factors as the SF-driven winds but carry ∼10 (∼50) times more momentum (energy). The results confirm our previous findings of high-duty-cycle, energy-driven outflows powered by AGN above the Schechter mass, which may contribute to SF quenching.
Abstract
We present a follow-up analysis examining the dynamics and structures of 41 massive, large star-forming galaxies at
z
∼ 0.67 − 2.45 using both ionized and molecular gas kinematics. We fit ...the galaxy dynamics with models consisting of a bulge, a thick, turbulent disk, and an NFW dark matter halo, using code that fully forward-models the kinematics, including all observational and instrumental effects. We explore the parameter space using Markov Chain Monte Carlo (MCMC) sampling, including priors based on stellar and gas masses and disk sizes. We fit the full sample using extracted 1D kinematic profiles. For a subset of 14 well-resolved galaxies, we also fit the 2D kinematics. The MCMC approach robustly confirms the results from least-squares fitting presented in Paper I: the sample galaxies tend to be baryon-rich on galactic scales (within one effective radius). The 1D and 2D MCMC results are also in good agreement for the subset, demonstrating that much of the galaxy dynamical information is captured along the major axis. The 2D kinematics are more affected by the presence of noncircular motions, which we illustrate by constructing a toy model with constant inflow for one galaxy that exhibits residual signatures consistent with radial motions. This analysis, together with results from Paper I and other studies, strengthens the finding that massive, star-forming galaxies at
z
∼ 1 − 2 are baryon-dominated on galactic scales, with lower dark matter fractions toward higher baryonic surface densities. Finally, we present details of the kinematic fitting code used in this analysis.
We present the completed KMOS3D survey, an integral field spectroscopic survey of 739 \(\mathrm{log}({M}_{\star }/{M}_{\odot })\gt 9\) galaxies at 0.6 < z < 2.7 using the K-band Multi Object ...Spectrograph (KMOS) at the Very Large Telescope. The KMOS3D survey provides a population-wide census of kinematics, star formation, outflows, and nebular gas conditions both on and off the star-forming galaxy main sequence through the spatially resolved and integrated properties of Hα, N ii, and S ii emission lines. We detect Hα emission for 91% of galaxies on the main sequence of star formation and 79% overall. The depth of the survey has allowed us to detect galaxies with star formation rates below 1 M ⊙ yr−1, as well as to resolve 81% of detected galaxies with ≥3 resolution elements along the kinematic major axis. The detection fraction of Hα is a strong function of both color and offset from the main sequence, with the detected and nondetected samples exhibiting different spectral energy distribution shapes. Comparison of Hα and UV+IR star formation rates reveal that dust attenuation corrections may be underestimated by 0.5 dex at the highest masses (\(\mathrm{log}({M}_{\star }/{M}_{\odot })\gt 10.5\)). We confirm our first year results of a high rotation-dominated fraction (monotonic velocity gradient and v rot/\({\sigma }_{0}\gt \sqrt{3.36}\)) of 77% for the full KMOS3D sample. The rotation-dominated fraction is a function of both stellar mass and redshift, with the strongest evolution measured over the redshift range of the survey for galaxies with \(\mathrm{log}({M}_{\star }/{M}_{\odot })\lt 10.5\). With this paper, we include a final data release of all 739 observed objects (http://www.mpe.mpg.de/ir/KMOS3D).
We study the properties of massive, galactic-scale outflows of molecular gas and investigate their impact on galaxy evolution. We present new IRAM PdBI CO(1–0) observations of local ultra-luminous ...infrared galaxies (ULIRGs) and quasar-hosts: a clear signature of massive and energetic molecular outflows, extending on kpc scales, is found in the CO(1–0) kinematics of four out of seven sources, with measured outflow rates of several 100 M⊙ yr-1. We combine these new observations with data from the literature, and explore the nature and origin of massive molecular outflows within an extended sample of 19 local galaxies. We find that starburst-dominated galaxies have an outflow rate comparable to their star formation rate (SFR), or even higher by a factor of ~2–4, implying that starbursts can indeed be effective in removing cold gas from galaxies. Nevertheless, our results suggest that the presence of an active galactic nucleus (AGN) can boost the outflow rate by a large factor, which is found to increase with the LAGN/Lbol ratio. The gas depletion time scales due to molecular outflows are anti-correlated with the presence and luminosity of an AGN in these galaxies, and range from a few hundred million years in starburst galaxies down to just a few million years in galaxies hosting powerful AGNs. In quasar hosts, the depletion time scales due to the outflow are much shorter than the depletion time scales due to star formation. We estimate the outflow kinetic power and find that, for galaxies hosting powerful AGNs, it corresponds to about 5% of the AGN luminosity, as expected by models of AGN feedback. Moreover, we find that momentum rates of about 20 LAGN/c are common among the AGN-dominated sources in our sample. For “pure” starburst galaxies, our data tentatively support models in which outflows are mostly momentum-driven by the radiation pressure from young stars onto dusty clouds. Overall, our results indicate that, although starbursts are effective in powering massive molecular outflows, the presence of an AGN may strongly enhance such outflows, and therefore have a profound feedback effect on the evolution of galaxies by efficiently removing fuel for star formation, hence quenching star formation.
A COVID-19 hospital guideline was implemented across all 18 acute hospitals in Wales in March 2020, promoting ward management of COVID pneumonitis and data collected across the first 3 Waves of the ...pandemic (Wave 1 March 1st 2020 to November 1st 2020, Wave 2 November 2st 2020 to February 21st 2021 and Wave 3 June 1st 2021 to December 14th 2021). The aim of this paper is to compare outcomes for patients by admission setting and type of ventilatory support given, with a particular focus on CPAP therapy.
This is a retrospective observational study of those aged over 18 admitted to hospital with community acquired COVID-19 between March 2020 and December 2021. The outcome of interest was in-hospital mortality. Univariate logistic regression models were used to compare crude outcomes across the waves. Multivariable logistic regression models were used to assess outcomes by different settings and treatments after adjusting for Wave, age, sex, co-morbidity and deprivation.
Of the 7,803 records collected, 5,887 (75.4%) met the inclusion criteria. Analysis of those cases identified statistically significant outcome improvements across the waves for all patients combined (Waves 1 to 3: 31.5% to 18.8%, p<0.01), all ward patients (28.9% to 17.7%, p<0.01), and all ICU patients (44.3% to 32.2%, p = 0.03). Sub group analyses identified outcome improvements in ward patients without any oxygen therapy (Waves 1 to 3: 22.2% to 12.7%, p<0.01), with oxygen therapy only (34.0% to 12.9%, p<0.01) and with CPAP only (63.5% to 39.2%, p<0.01). The outcome improvements for ICU patients receiving CPAP only (35.7% to 24.6%, p = 0.31) or invasive ventilation (61.6% to 54.6%, p = 0.43) were not statistically significant though the numbers being admitted to ICU were small. The logistic regression models identified important age and comorbidity effects on outcomes. The multivariable model that took these into account suggested no statistically significantly greater risk of death for those receiving CPAP on the ward compared to those receiving CPAP in ICU (OR 0.89, 95% CI: 0.49 to 1.60).
There were successive reductions in mortality in inpatients over the three Waves reflecting new treatments and better management of complications. Mortality for those requiring CPAP was similar in respiratory wards and ICUs after adjusting for differences in their respective patient populations.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
The membrane-bound Toll-like receptors (TLRs) trigger innate immune responses after recognition of a wide variety of pathogen-derived compounds. Despite the wide range of ligands recognized by TLRs, ...the receptors share a common structural framework in their extracellular, ligand-binding domains. These domains all adopt horseshoe-shaped structures built from leucine-rich repeat motifs. Typically, on ligand binding, two extracellular domains form an “m”-shaped dimer sandwiching the ligand molecule bringing the transmembrane and cytoplasmic domains in close proximity and triggering a downstream signaling cascade. Although the ligand-induced dimerization of these receptors has many common features, the nature of the interactions of the TLR extracellular domains with their ligands varies markedly between TLR paralogs.
► TLRs recognize pathogen-derived ligands by their ectodomains ► TLR ECDs are horseshoe-shaped structures built from leucine-rich repeats ► TLR-ligands dimerize ectodomains via their lateral faces, forming “m”-shaped structures ► Dimerization leads to downstream signaling whose structural basis is still unknown
Abstract
Determining the ages of red-giant stars is a key problem in stellar astrophysics. One of the difficulties in this determination is to know the evolutionary state of the individual stars – ...i.e. have they started to burn Helium in their cores? That is the topic of this paper. Asteroseismic data provide a route to achieving this information. What we present here is a highly autonomous way of determining the evolutionary state from an analysis of the power spectrum of the light curve. The method is fast and efficient and can provide results for a large number of stars. It uses the structure of the dipole-mode oscillations, which have a mixed character in red-giant stars, to determine some measures that are used in the categorization. It does not require that all the individual components of any given mode be separately characterized. Some 6604 red-giant stars have been classified. Of these, 3566 are determined to be on the red-giant branch, 2077 are red-clump and 439 are secondary-clump stars. We do not specifically identify the low-metallicity, horizontal-branch stars. The difference between red-clump and secondary-clump stars is dependent on the manner in which Helium burning is first initiated. We discuss that the way the boundary between these classifications is set may lead to mis-categorization in a small number of stars. The remaining 522 stars were not classified either because they lacked sufficient power in the dipole modes (so-called depressed dipole modes) or because of conflicting values in the parameters.