Featured Reviews in Organic Chemistry Dembinski, Roman; Soloshonok, Vadim
Molecules (Basel, Switzerland),
08/2023, Letnik:
28, Številka:
16
Journal Article
Recenzirano
Odprti dostop
The field of Organic Chemistry represents one of the most traditional areas of chemistry that has delivered many benefits to the community of chemists ...
This review includes recent developments in the synthesis of benzo4,5imidazo2,1-
isoquinolines with particular attention given to categorizing protocols based on the structural features of the ring ...architecture and crystallographically characterized reaction products.
We wish to draw attention to an important issue concerning scientific practice with regard to enhancing the quality of publications in Molecules (as well as for other journals) ...
Dicobalt hexacarbonyl nucleoside complexes of propargyl ether or esters of 5-substituted uridines react with diverse C-nucleophiles. Synthetic outcomes confirmed that the Nicholas reaction can be ...carried out in a nucleoside presence, leading to a divergent synthesis of novel metallo-nucleosides enriched with alkene, arene, arylketo, and heterocyclic functions, in the deoxy and ribo series.
reaction: see text 5-Endo-dig electrophilic cyclization of 1,4-diaryl but-3-yn-1-ones with N-bromosuccinimide or N-iodosuccinimide/acetone and iodine monochloride/CH(2)Cl(2), at room temperature, in ...the absence of base, provides 3-halo-2,5-diarylfurans with excellent regiocontrol and high yields (81-94%).
5-Endo-dig cycloisomerization of 1,4-di- and 1,2,4-trisubstituted but-3-yn-1-ones in the presence of a catalytic amount of zinc chloride (10 mol %) in dichloromethane at room temperature (22 °C) ...provides 2,5-di- and 2,3,5-trisubstituted furans in high yields (85−97%).
On behalf of my Section Editor-in-Chief co-author colleagues I am pleased to announce a Special Issue to commemorate the recent publication of
20,000th paper ....
Fluorination of 1,4‐disubstituted tert‐butyldimethylsilyl but‐1‐en‐3‐yn‐1‐yl ethers with Selectfluor gives 2‐mono‐fluorobut‐3‐yn‐1‐ones. Subsequent 5‐endo‐dig cyclization in the presence of ...chlorotriphenylphosphine gold(I)/silver trifluoromethanesulfonate (both 5 mol%, dichloromethane) under ambient conditions, provides a facile method for the generation of mainly 2,5‐diaryl‐substituted 3‐fluorofurans in high yields (89–96%). The structure of 2‐(4‐bromophenyl)‐3‐fluoro‐5‐(4‐methylphenyl)furan was confirmed by X‐ray crystallography.
Ligand-free 5-
endo-
dig cyclization of 1,4- and 1,2,4-substituted but-3-yn-1-yl (homopropargyl) azides in the presence of zinc chloride (usually 20
mol
%) in dichloroethane at elevated temperature ...provides 2,5-di- and 2,3,5-trisubstituted pyrroles in high to moderate yields (91–41%). Both conventional and microwave protocols furnished comparable results. A structure of 2-(4-fluorophenyl)-5-(4-methylphenyl)-1
H-pyrrole was confirmed by X-ray crystallography.
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