Background
Traumatic tympanic membrane (TM) perforations usually heal spontaneously. The aim of this study was to investigate whether the topical application of Triticum Vulgare (TV) in ...experimentally induced traumatic TM perforations in the rats has a positive effect on wound healing process.
Methods
The rats were randomly assigned to four experimental groups. Drugs were introduced twice a day for 7 days. On the 7th day, specimens were sent for histological examination.
Results
Mean values found in group NC in terms of epithelial regeneration mean scores are as follows: fibroblast and collagen density, neovascularization, and density of inflammation cells were lower than all groups (
p
< 0.05).
It was found that reepithelization on the post-perforation 7th day was better in the HO group than the TV group. In terms of the subepithelial fibroblast cells, density of collagen fibers, formation of new veins, and inflammatory cell accumulation, it was observed that the group TV was better than the group HO.
Conclusion
This is the first study investigating the potential curative role of TV in an experimental rat model of tympanic membrane perforation. Considering these findings, it is concluded that TV can be more effective than HO on wound healing in TM perforation.
Background
This study was to investigate the frequency of self-reported dizziness symptom in cases with Crimean-Congo hemorrhagic fever (CCHF) and the severity of dizziness, if any, by using various ...scales. The frequency and severity of the self-reported dizziness symptom of CCHF patients, level of disability caused by dizziness, and to what extent vestibular symptoms affected activities of daily living were assessed by various scales. The frequency and severity of the self-reported dizziness symptom of CCHF patients, level of disability caused by dizziness, and to what extent vestibular symptoms affected activities of daily living were assessed by various scales.
Results
The frequency of dizziness in CCHF cases included in the study was 11.11% and all the cases were involved in the mild category in terms of disease severity. When the results of the scales applied to all of the cases were evaluated in general, it was seen that there was no vertigo or dizziness.
Conclusion
According to the results of the present study, we consider that multicenter studies with large series investigating pathophysiological mechanisms underlying these clinical symptoms are needed in order to evaluate dizziness symptom and to make definitive interpretations in CCHF disease.
The aim is to investigate the contribution of the PNIF test in daily clinical practices in the objective evaluation of the early postoperative functional results of septoplasty and the effect of the ...severity, direction, and type of nasal septum deviation on mean PNIF values. Nasal septum deviation (NSDs) of the cases were grouped according to the Mladina classification and the severity of NSDs. An objective evaluation of the nasal airway was conducted via a peak flowmeter device in the preoperative and postoperative first month. When examining the mean PNIF values according to genders, it was observed that the values determined in male cases in the preoperative and postoperative period were higher. In the intragroup evaluation performed according the Mladina classification, a statistically significant increase was observed in the preoperative and postoperative PNIF values of the cases in Types 1–4. In the intragroup evaluation performed according to the severity of NSD, there was a significant increase in the preoperative and postoperative PNIF values of the mild and moderate cases. When comparing the preoperative and postoperative PNIF values of the groups in terms of the severity of NSD, it was observed that there was a significant difference. The PNIF can be used in routine clinical practices to evaluate the septoplasty results objectively. In the evaluation of functional results, the change in the mean PNIF values may also vary according to the direction and severity of septum deviation and the Mladina classification other than age, gender and ethnic origin.
Aim: The aim of this study was to evaluate the efficiency of the treatment in the cases, who were diagnosed with Eustachian tube dysfunction (ETD) via history, physical examination, and tympanometry ...and for whom intranasal steroid treatment was planned to be used before surgical treatment options, by using Eustachian Tube Dysfunction Questionnaire (ETDQ)-7. Materials and Methods: Fifty-five cases, who applied to the otorhinolaryngology outpatient clinic due to the complaints suggesting Eustachian dysfunction such as aural fullness and pressure sensation and for whom the diagnosis of Eustachian dysfunction was considered due to the results of the examination, history, and physical examination, were included in the study. The 3rd and 6th weeks of intranasal steroid treatment ETDQ-7 scores were recorded. Results: ETDQ-7 mean scores of the cases were 2.72 ± 0.97 at the time of initial diagnosis (minimum-maximum: 1-4.71), 2.31 ± 0.85 in the 3rd week of the treatment (minimum-maximum: 1-5), and 2.12 ± 0.78 (minimum-maximum: 1-4, 14) in the 6th week. A statistically significant difference was observed when statistically assessing the ETDQ-7 scores determined at the time of diagnosis and in the 3rd and 6th weeks of the treatment (P < 0.001). When ETDQ-7 scores were assessed based on gender in assessment time, there was a statistically significant difference in the assessment conducted in the 3rd week (P < 0.05; P = 0.039). Conclusion: It is believed that the current study is the first study that evaluates the efficiency of intranasal corticosteroid treatment, which is frequently used by the doctors in daily practice in pharmacotherapy in the cases with ETD from young adult and adult age groups, on the symptoms via ETDQ-7. In addition, the results of the present study indicated that intranasal steroid treatment in early periods caused a significant recovery in the symptoms, however this recovery also reached a plateau after the treatment.
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