Grade repetition is practiced worldwide and varies considerably across the globe. Globally, around 32.2 million students repeated a grade at the primary education level in 2010. Although a large body ...of research has documented grade repetition's academic and non-academic effects, the limited evidence on associations between grade repetition and school bullying is inconsistent and ambiguous. This study aimed to investigate the global association of grade repetition with bullying victimization in a large-scale school-based cross-sectional study.
We used the latest global data from the Program for International Student Assessment (PISA) 2018. PISA 2018 was conducted between March and August 2018 in 80 countries and economies among students aged 15-16 years attending secondary education. The students reported their experiences of repeating a grade at any time point before the survey and of being bullied in the past 12 months. The outcome measures were 6 types of bullying victimization. We accounted for the complex survey design and used multivariate logistic regression models to estimate the odds ratios (ORs) with 95% confidence intervals (CIs) of grade repetition with bullying victimization after adjusting for potential confounders (sex; age group; migrant status; school type; economic, social, and cultural status; and parental emotional support). This study included 465,146 students (234,218 girls and 230,928 boys) with complete data on grade repetition and bullying victimization in 74 countries and economies. The lifetime prevalence of grade repetition was 12.26%, and 30.32% of students experienced bullying at least a few times a month during the past 12 months. Grade repetition was statistically significantly associated with each type of bullying victimization. The OR (95% CI) of overall bullying victimization for grade repeaters compared with their promoted peers was 1.42 (95% CI 1.32-1.52, p < 0.001). The sex-specific analysis produced similar results in both boys and girls. Furthermore, girls who repeated a grade had higher risks of being made fun of, being threatened, having possessions taken away, and being pushed around than boys. The major limitation is that this study only included students attending schools and therefore may be subject to possible selection bias. In addition, the cross-sectional design hinders us from establishing causality between grade repetition and bullying victimization.
In this study, we observed that, globally, both boys and girls who repeat a grade are at increased risk of being bullied compared with promoted peers, but girls may experience higher risks than boys of specific types of bullying associated with repeating a grade. These findings provide evidence for the association of grade repetition with bullying victimization. Sex differences in risk of experiencing some types of bullying suggest that tailored interventions for girls who repeat a grade may be warranted.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Grade repetition is practiced worldwide and varies considerably across the globe. Globally, around 32.2 million students repeated a grade at the primary education level in 2010. Although a large body ...of research has documented grade repetition's academic and non-academic effects, the limited evidence on associations between grade repetition and school bullying is inconsistent and ambiguous. This study aimed to investigate the global association of grade repetition with bullying victimization in a large-scale school-based cross-sectional study. We used the latest global data from the Program for International Student Assessment (PISA) 2018. PISA 2018 was conducted between March and August 2018 in 80 countries and economies among students aged 15-16 years attending secondary education. The students reported their experiences of repeating a grade at any time point before the survey and of being bullied in the past 12 months. The outcome measures were 6 types of bullying victimization. We accounted for the complex survey design and used multivariate logistic regression models to estimate the odds ratios (ORs) with 95% confidence intervals (CIs) of grade repetition with bullying victimization after adjusting for potential confounders (sex; age group; migrant status; school type; economic, social, and cultural status; and parental emotional support). This study included 465,146 students (234,218 girls and 230,928 boys) with complete data on grade repetition and bullying victimization in 74 countries and economies. The lifetime prevalence of grade repetition was 12.26%, and 30.32% of students experienced bullying at least a few times a month during the past 12 months. Grade repetition was statistically significantly associated with each type of bullying victimization. The OR (95% CI) of overall bullying victimization for grade repeaters compared with their promoted peers was 1.42 (95% CI 1.32-1.52, p < 0.001). The sex-specific analysis produced similar results in both boys and girls. Furthermore, girls who repeated a grade had higher risks of being made fun of, being threatened, having possessions taken away, and being pushed around than boys. The major limitation is that this study only included students attending schools and therefore may be subject to possible selection bias. In addition, the cross-sectional design hinders us from establishing causality between grade repetition and bullying victimization. In this study, we observed that, globally, both boys and girls who repeat a grade are at increased risk of being bullied compared with promoted peers, but girls may experience higher risks than boys of specific types of bullying associated with repeating a grade. These findings provide evidence for the association of grade repetition with bullying victimization. Sex differences in risk of experiencing some types of bullying suggest that tailored interventions for girls who repeat a grade may be warranted.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
BackgroundGrade repetition is practiced worldwide and varies considerably across the globe. Globally, around 32.2 million students repeated a grade at the primary education level in 2010. Although a ...large body of research has documented grade repetition's academic and non-academic effects, the limited evidence on associations between grade repetition and school bullying is inconsistent and ambiguous. This study aimed to investigate the global association of grade repetition with bullying victimization in a large-scale school-based cross-sectional study.Methods and findingsWe used the latest global data from the Program for International Student Assessment (PISA) 2018. PISA 2018 was conducted between March and August 2018 in 80 countries and economies among students aged 15-16 years attending secondary education. The students reported their experiences of repeating a grade at any time point before the survey and of being bullied in the past 12 months. The outcome measures were 6 types of bullying victimization. We accounted for the complex survey design and used multivariate logistic regression models to estimate the odds ratios (ORs) with 95% confidence intervals (CIs) of grade repetition with bullying victimization after adjusting for potential confounders (sex; age group; migrant status; school type; economic, social, and cultural status; and parental emotional support). This study included 465,146 students (234,218 girls and 230,928 boys) with complete data on grade repetition and bullying victimization in 74 countries and economies. The lifetime prevalence of grade repetition was 12.26%, and 30.32% of students experienced bullying at least a few times a month during the past 12 months. Grade repetition was statistically significantly associated with each type of bullying victimization. The OR (95% CI) of overall bullying victimization for grade repeaters compared with their promoted peers was 1.42 (95% CI 1.32-1.52, p < 0.001). The sex-specific analysis produced similar results in both boys and girls. Furthermore, girls who repeated a grade had higher risks of being made fun of, being threatened, having possessions taken away, and being pushed around than boys. The major limitation is that this study only included students attending schools and therefore may be subject to possible selection bias. In addition, the cross-sectional design hinders us from establishing causality between grade repetition and bullying victimization.ConclusionsIn this study, we observed that, globally, both boys and girls who repeat a grade are at increased risk of being bullied compared with promoted peers, but girls may experience higher risks than boys of specific types of bullying associated with repeating a grade. These findings provide evidence for the association of grade repetition with bullying victimization. Sex differences in risk of experiencing some types of bullying suggest that tailored interventions for girls who repeat a grade may be warranted.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Managing and querying moving objects in a highly distributed environment remains a challenge. In this paper, we discuss a fully distributed environment and treat moving object as mobile agents. We ...analyze the communication scenarios and class hierarchy of moving objects in a distributed environment as mobile agents, and use the extended G-Net to model the communication among different agents. The analysis of the communication model is primarily based upon the context of moving objects/location management.
In this paper we investigate the development of moving object system based on the GPS/GIS. Its main characteristics concern the possibility to access various information sources and to provide the ...basic functionalities of a navigation system, e.g. positioning. This system uses a differential Global Positioning System (GPS) device to acquire the position of a mobile (e.g, vehicle). A PDA with an Internet based connection permits one to access distance data sources and to transfer data between the components of the system. A Web browser and a Java applet are used for data integration and visualization.
By introducing a flux-controlled memristor with quadratic nonlinearity into the Liu–Chen system as a feedback term, a novel four-wing memristive chaotic system is derived in this paper. This ...memristive chaotic system with a line of equilibrium, which presented striking extreme multistability that has received extensive attention and research in recent years, can generate single-wing 1-periodic, single-wing 2-periodic, single-wing chaotic and other double-wing state rotational coexisting attractors depending on the memristor initial conditions. Furthermore, complex transient transition and sustained chaotic state behaviors can also be observed, the complex phenomenon of memristive chaotic system with infinite equilibrium is further revealed. The dynamical behaviors are numerically verified through investigating phase portraits, Lyapunov exponent spectra, bifurcation diagrams and basin of attraction. Finally, Multisim simulations and hardware experiments are carried out to validate the theoretical analysis.
•A novel four-wing memristive chaotic system with a line of equilibrium is proposed.•This system shows many complex dynamical behaviors such as extreme multistability.•The attractor rotation in memristive chaotic system is proposed for the first time.•The attractor rotation of the novel system is verified by the hardware circuit.
ABSTRACT Type Ia supernova (SN Ia) as a standard candle is an ideal tool to measure cosmic distance and expansion history of the Universe. Here, we investigate the SN Ia photometric measurement in ...the China Space Station Telescope Ultra Deep Field (CSST-UDF) survey, and study the constraint power on the cosmological parameters, such as the equation of state of dark energy. The CSST-UDF survey is expected to cover a 9 deg2 sky area in 2 yr with 250 s × 60 exposures for each band. The magnitude limit can reach i ≃ 26 AB mag for 5σ point source detection with a single exposure. We generate light-curve mock data for SNe Ia and different types of core-collapse SNe (CCSNe). sncosmo is chosen as the framework by utilizing the salt3 model to simulate SN Ia data. After selecting high-quality data and fitting the light curves, we derive the light-curve parameters and identify CCSNe as contamination, resulting in ∼2200 SNe with an $\sim\!\! 7{{\ \rm per\, cent}}$ CCSN contamination rate. We adopt a calibration method similar to Chauvenet’s criterion, and apply it to the distance modulus data to further reduce the contamination. We find that this method is effective and can suppress the contamination fraction to $\sim\!\! 3.5{{\ \rm per\, cent}}$ with 2012 SNe Ia and 73 CCSNe. In the cosmological fitting stage, we did not distinguish between SNe Ia and CCSNe. We find that the constraint accuracies on ΩM, ΩΛ, and w are about two times better than the current SN surveys, and they could be further improved by a factor of ∼1.4 if including the baryon acoustic oscillation data from the CSST spectroscopic wide-field galaxy survey.
Gastric mucosal injuries include focal and diffused injuries, which do and do not change the cell differentiation pattern. Parietal cells loss is related to the occurrence of gastric mucosal diffused ...injury, with two phenotypes of spasmolytic polypeptide-expressing metaplasia and neuroendocrine cell hyperplasia, which is the basis of gastric cancer and gastric neuroendocrine tumor respectively. Multiple ion channels and transporters are located and expressed in the parietal cells, which is not only regulate the gastric acid-base homeostasis, but also regulate the growth and development of parietal cells. Therefore, alteration and dysregulation of ion channels and transporters in the parietal cells impairs the morphology and physiological functions of stomach, resulted in gastric diffused mucosal damage. In this review, multiple ion channels and transporters in parietal cells, including K+ channels, aquaporins, Cl- channels, Na+/H+ transporters, and Cl-/HCO3- transporters are described, and their roles in gastric diffused mucosal injury are discussed. We hope to drive researcher’s attention to focus on the role of ion channels/transporters loss in the parietal cells induced gastric diffused mucosal injury.
Dysfunction of ion channels and transporters in the parietal cells induced two phenotypes of gastric diffused mucosal injury. (Red arrows indicate downregulation and black arrows indicate upregulation; SPEM: spasmolytic polypeptide-expressing metaplasia; IM: intestinal metaplasia; G-NET: gastric neuroendocrine tumor.) Display omitted
•Ion channels/transporters in parietal cells could regulate cell differentiation.•Dysfunction of ion channels/transporters induces gastric diffused mucosal injury.•SPEM and gastric neuroendocrine cell hyperplasia could lead to GC and I type GNET.
Colorectal cancer is a malignant tumor that poses a serious threat to human health. The main objective of this study is to investigate the mechanism by which Jatrorrhizine (JAT), a root extract from ...Stephania Epigaea Lo, exerts its anticancer effects in colorectal cancer. We initially assessed the inhibitory properties of JAT on SW480 cells using MTT and cell scratch assays. Flow cytometry was employed to detect cell apoptosis. Differentially expressed genes were identified through high-throughput sequencing, and they were subjected to functional enrichment and signaling pathway analysis and PPI network construction. RT-qPCR was used to evaluate gene expression and identify critical differentially expressed genes. Finally, the function and role of differentially expressed genes produced by JAT-treated SW480 cells in colorectal cancer will be further analyzed using the TCGA database. Our study demonstrated that JAT exhibits inhibitory effects on SW480 cells at concentrations of 12.5microM, 25microM, 50microM, and 75microM without inducing cell apoptosis. Through high-throughput sequencing, we identified 244 differentially expressed genes. KEGG and GO analysis of high-throughput sequencing results showed that differentially expressed genes were significantly enriched in MAPK, Wnt, and P53 signaling pathways. Notably, JAT significantly altered the expression of genes associated with ferroptosis. Subsequent RT-qPCR showed that the expression of ferroptosis genes SLC2A3 and ASNS was significantly lower in JAT-treated SW480 cells than in the control group. Analysis by TCGA data also showed that ferroptosis genes SLC2A3 and ASNS were significantly highly expressed in COAD. The prognosis of SLC2A3 was significantly worse in COAD compared to the normal group. SLC2A3 may be a core target of JAT for the treatment of COAD. JAT can inhibit COAD growth by ferroptosis-related genes. And it is a potential natural substance for the treatment of COAD.
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