MYCENAE REVISITED PART 4: ASSESSING THE NEW DATA Dickinson, O.T.P.K.; Papazoglou-Manioudaki, Lena; Nafplioti, Argyro ...
Annual of the British School at Athens,
11/2012, Letnik:
107
Journal Article
Recenzirano
This is the fourth and final part of the series inspired by the rediscovery in 2003 of two skeletons excavated in 1877 in Shaft Grave VI in Circle A at Mycenae by Panayiotis Stamatakis. The ...contribution of Stamatakis to the excavations, the discrepancies between his unpublished reports to the Archaeological Society and Schliemann's account, and the reliability of that account, are discussed. This is followed by a survey of what can now be said about Grave Circle A, following the restudy of the surviving bones from Graves III–VI and the publication of various details of the arrangement in the graves reported by Stamatakis, and by a final somewhat speculative discussion of what the graves contribute to the study of the development of Mycenae at the time of its rapid rise to prominence and the accompanying major changes in the structure of society, at Mycenae and elsewhere on the Greek mainland. Μυκηνών επανεξέταση Μέρος 4 Το παρόν είναι το τέταρτο και τελευταίο μια σειράς άρθρων εμπνευσμένων από την εκ νέου ανακάλυψη, το 2003, δύο σκελετών που ανέσκαψε ο Παναγιώτης Σταματάκης το 1877 στο λακκοειδή Τάφο VI του Ταφικού Κύκλου Α των Μυκηνών.Συζητώνται η συνεισφορά του Σταματάκη στην ανασκαφική έρευνα, οι ασυμφωνίες μεταξύ των αδημοσίευτων αναφορών του προς την Αρχαιολογική Εταιρεία και των όσων αναφέρει ο Schliemann, και η αξιοπιστία των τελευταίων.Τη συζήτηση αυτή ακολουθεί μια επισκόπηση των νέων στοιχείων για τον Ταφικό Κύκλο Α, μετά την επανεξέταση των σωζόμενων οστών από τους Τάφους ΙΙΙ-VI και τη δημοσίευση λεπτομερών πληροφορίων από τις αναφορές του Σταματάκη για τη διάταξη των ευρημάτων στο εσωτερικό των τάφων. Ακολουθεί μια θεωρητική, τρόπον τινά, συζήτηση της συμβολής που έχουν τα συμπεράσματα για τον Ταφικό Κύκλο Α στη μελέτη της ανάπτυξης των Μυκηνών κατά την περίοδο της ταχείας ανόδου τους σε προεξάρχουσα θέση και των συνακόλουθων μείζονων αλλαγών στη δομή της κοινωνίας, στις Μυκήνες και αλλού στην ηπειρωτική Ελλάδα.
The aim of this study was to identify useful patterns of abnormal fluorine-18 fluorodeoxyglucose (FDG) uptake by different types of non-small cell (NSC) lung cancer and to assess their clinical ...implications. One hundred and three sequential patients with newly diagnosed, pathology-proven NSC lung cancer were included. FDG positron emission tomography (PET) images were acquired using a dedicated PET scanner. There were 35 squamous cell carcinomas (SQC), 17 large cell cancers (LGC), 38 adenocarcinomas (ADC), 1 bronchioloalveolar carcinoma (BAC) and 12 non-classified NSC cancers. PET images were categorized into detectable patterns of necrotic center in the primary tumor, satellite lesions (T4), hilar lymph nodes (N1), and N2, N3, and M1 lesions by visual interpretation of PET images for SQC, LGC, and ADC (n=90; BAC and non-classified NSC cancers were excluded). The PET lesions were correlated with surgical pathology and with CT findings in inoperable cases. Necrosis was more commonly present in the primary tumors of LGC (53%) and SQC (43%) than in those of ADC (26%) (P<0.0001 and <0.01, respectively). The frequencies of nodal uptake in ADC, SQC and LGC were similar (71%, 60%, and 59%, respectively). However, M1 lesions were present significantly more often in LGC (41%) and ADC (34%) than in SQC (3%) (both P<0.0001). Significantly more surgically inoperable cases were found by PET (T4, N3, M1) in ADC (50%) and LGC (41%) than in SQC (26%) (P<0.001 and <0.02, respectively). Our results suggest a wide variation of PET findings for different types of NSC lung cancer. Identification of these patterns is useful in clinical PET interpretation, in that knowledge of the most probable association between the PET patterns and the histological types will facilitate initial staging and planning of management.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
In a trial involving patients with relapsed or refractory large B-cell lymphoma, the CAR T-cell therapy axicabtagene ciloleucel led to significantly longer event-free survival than standard salvage ...chemotherapy (which was followed by high-dose therapy and autologous stem-cell transplantation in patients with a response). High-grade toxic effects were common, but most patients recovered.
We present the public release of the stellar mass catalogs for the GOODS-S and UDS fields obtained using some of the deepest near-IR images available, achieved as part of the Cosmic Assembly ...Near-infrared Deep Extragalactic Legacy Survey project. We combine the effort from 10 different teams, who computed the stellar masses using the same photometry and the same redshifts. Each team adopted their preferred fitting code, assumptions, priors, and parameter grid. The combination of results using the same underlying stellar isochrones reduces the systematics associated with the fitting code and other choices. Thanks to the availability of different estimates, we can test the effect of some specific parameters and assumptions on the stellar mass estimate. The choice of the stellar isochrone library turns out to have the largest effect on the galaxy stellar mass estimates, resulting in the largest distributions around the median value (with a semi interquartile range larger than 0.1 dex). On the other hand, for most galaxies, the stellar mass estimates are relatively insensitive to the different parameterizations of the star formation history. The inclusion of nebular emission in the model spectra does not have a significant impact for the majority of galaxies (less than a factor of 2 for ~80% of the sample). Nevertheless, the stellar mass for the subsample of young galaxies (age <100 Myr), especially in particular redshift ranges (e.g., 2.2 < z < 2.4, 3.2 < z < 3.6, and 5.5 < z < 6.5), can be seriously overestimated (by up to a factor of 10 for <20 Myr sources) if nebular contribution is ignored.
The complex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in terms of gene discovery using genome-wide association study (GWAS) methods. In an attempt ...to overcome these barriers, the current study utilized GWAS meta-analysis to examine the association of common genetic variation (~8M single-nucleotide polymorphisms (SNP) with minor allele frequency ⩾1%) to general cognitive function in a sample of 35 298 healthy individuals of European ancestry across 24 cohorts in the Cognitive Genomics Consortium (COGENT). In addition, we utilized individual SNP lookups and polygenic score analyses to identify genetic overlap with other relevant neurobehavioral phenotypes. Our primary GWAS meta-analysis identified two novel SNP loci (top SNPs: rs76114856 in the CENPO gene on chromosome 2 and rs6669072 near LOC105378853 on chromosome 1) associated with cognitive performance at the genome-wide significance level (P<5 × 10
). Gene-based analysis identified an additional three Bonferroni-corrected significant loci at chromosomes 17q21.31, 17p13.1 and 1p13.3. Altogether, common variation across the genome resulted in a conservatively estimated SNP heritability of 21.5% (s.e.=0.01%) for general cognitive function. Integration with prior GWAS of cognitive performance and educational attainment yielded several additional significant loci. Finally, we found robust polygenic correlations between cognitive performance and educational attainment, several psychiatric disorders, birth length/weight and smoking behavior, as well as a novel genetic association to the personality trait of openness. These data provide new insight into the genetics of neurocognitive function with relevance to understanding the pathophysiology of neuropsychiatric illness.
HESS J0632+057 is the only gamma-ray binary known so far whose position in the sky allows observations with ground-based observatories in both the northern and southern hemispheres. Here we report on ...long-term observations of HESS J0632+057 conducted with the Very Energetic Radiation Imaging Telescope Array System and High Energy Stereoscopic System Cherenkov telescopes and the X-ray satellite Swift, spanning a time range from 2004 to 2012 and covering most of the system's orbit. The very-high-energy (VHE) emission is found to be variable and is correlated with that at X-ray energies. An orbital period of 315 super(+6) sub(-4) days is derived from the X-ray data set, which is compatible with previous results, P = (321 + or - 5) days. The VHE light curve shows a distinct maximum at orbital phases close to 0.3, or about 100 days after periastron passage, which coincides with the periodic enhancement of the X-ray emission. Furthermore, the analysis of the TeV data shows for the first time a statistically significant (>6.5sigma) detection at orbital phases 0.6-0.9. The obtained gamma-ray and X-ray light curves and the correlation of the source emission at these two energy bands are discussed in the context of the recent ephemeris obtained for the system. Our results are compared to those reported for other gamma-ray binaries.
Planck intermediate results Adam, R; Aghanim, N; Ashdown, M ...
Astronomy and astrophysics (Berlin),
12/2016, Letnik:
596
Journal Article
Recenzirano
Odprti dostop
We investigate constraints on cosmic reionization extracted from the Planck cosmic microwave background (CMB) data. We combine the Planck CMB anisotropy data in temperature with the low-multipole ...polarization data to fit LambdaCDM models with various parameterizations of the reionization history. We obtain a Thomson optical depth tau= 0.058 + or - 0.012 for the commonly adopted instantaneous reionization model. This confirms, with data solely from CMB anisotropies, the low value suggested by combining Planck 2015 results with other data sets, and also reduces the uncertainties. We reconstruct the history of the ionization fraction using either a symmetric or an asymmetric model for the transition between the neutral and ionized phases. To determine better constraints on the duration of the reionization process, we also make use of measurements of the amplitude of the kinetic Sunyaev-Zeldovich (kSZ) effect using additional information from the high-resolution Atacama Cosmology Telescope and South Pole Telescope experiments. The average redshift at which reionization occurs is found to lie between z= 7.8 and 8.8, depending on the model of reionization adopted. Using kSZ constraints and a redshift-symmetric reionization model, we find an upper limit to the width of the reionization period of Deltaz< 2.8. In all cases, we find that the Universe is ionized at less than the 10% level at redshifts above z = 10. This suggests that an early onset of reionization is strongly disfavoured by the Planck data. We show that this result also reduces the tension between CMB-based analyses and constraints from other astrophysical sources.
This paper describes the observations and the first data release (DR1) of the ESO public spectroscopic survey “VANDELS, a deep VIMOS survey of the CANDELS CDFS and UDS fields”. The main targets of ...VANDELS are star-forming galaxies at redshift 2.4 < z < 5.5, an epoch when the Universe had not yet reached 20% of its current age, and massive passive galaxies in the range 1 < z < 2.5. By adopting a strategy of ultra-long exposure times, ranging from a minimum of 20 h to a maximum of 80 h per source, VANDELS is specifically designed to be the deepest-ever spectroscopic survey of the high-redshift Universe. Exploiting the red sensitivity of the refurbished VIMOS spectrograph, the survey is obtaining ultra-deep optical spectroscopy covering the wavelength range 4800–10 000 Å with a sufficiently high signal-to-noise ratio to investigate the astrophysics of high-redshift galaxy evolution via detailed absorption line studies of well-defined samples of high-redshift galaxies. VANDELS-DR1 is the release of all medium-resolution spectroscopic data obtained during the first season of observations, on a 0.2 square degree area centered around the CANDELS-CDFS (Chandra deep-field south) and CANDELS-UDS (ultra-deep survey) areas. It includes data for all galaxies for which the total (or half of the total) scheduled integration time was completed. The DR1 contains 879 individual objects, approximately half in each of the two fields, that have a measured redshift, with the highest reliable redshifts reaching zspec ~ 6. In DR1 we include fully wavelength-calibrated and flux-calibrated 1D spectra, the associated error spectrum and sky spectrum, and the associated wavelength-calibrated 2D spectra. We also provide a catalog with the essential galaxy parameters, including spectroscopic redshifts and redshift quality flags measured by the collaboration. We present the survey layout and observations, the data reduction and redshift measurement procedure, and the general properties of the VANDELS-DR1 sample. In particular, we discuss the spectroscopic redshift distribution and the accuracy of the photometricredshifts for each individual target category, and we provide some examples of data products for the various target typesand the different quality flags. All VANDELS-DR1 data are publicly available and can be retrieved from the ESO archive. Two further data releases are foreseen in the next two years, and a final data release is currently scheduled for June 2020, which will include an improved rereduction of the entire spectroscopic data set.
Planck 2015 results Ade, P A R; Aumont, J; Baccigalupi, C ...
Astronomy and astrophysics (Berlin),
10/2016, Letnik:
594
Journal Article
Recenzirano
Odprti dostop
We present the current accounting of systematic effect uncertainties for the Low Frequency Instrument (LFI) that are relevant to the 2015 release of the Planck cosmological results, showing the ...robustness and consistency of our data set, especially for polarization analysis. We use two complementary approaches: (i) simulations based on measured data and physical models of the known systematic effects; and (ii) analysis of difference maps containing the same sky signal ("null-maps"). The LFI temperature data are limited by instrumental noise. At large angular scales the systematic effects are below the cosmic microwave background (CMB) temperature power spectrum by several orders of magnitude. In polarization the systematic uncertainties are dominated by calibration uncertainties and compete with the CMB E-modes in the multipole range 10-20. Based on our model of all known systematic effects, we show that these effects introduce a slight bias of around 0.2sigma on the reionization optical depth derived from the 70GHz EE spectrum using the 30 and 353GHz channels as foreground templates. At 30GHz the systematic effects are smaller than the Galactic foreground at all scales in temperature and polarization, which allows us to consider this channel as a reliable template of synchrotron emission. We assess the residual uncertainties due to LFI effects on CMB maps and power spectra after component separation and show that these effects are smaller than the CMB amplitude at all scales. We also assess the impact on non-Gaussianity studies and find it to be negligible. Some residuals still appear in null maps from particular sky survey pairs, particularly at 30 GHz, suggesting possible straylight contamination due to an imperfect knowledge of the beam far sidelobes.
Planck intermediate results Ade, P; Aghanim, N; Alves, M ...
Astronomy and astrophysics (Berlin),
02/2016, Letnik:
586
Journal Article
Recenzirano
Odprti dostop
Within ten nearby (d< 450pc) Gould belt molecular clouds we evaluate statistically the relative orientation between the magnetic field projected on the plane of sky, inferred from the polarized ...thermal emission of Galactic dust observed by Planck at 353GHz, and the gas column density structures, quantified by the gradient of the column density, N sub(H). The selected regions, covering several degrees in size, are analysed at an effective angular resolution of 10' FWHM, thus sampling physical scales from 0.4 to 40pc in the nearest cloud. The column densities in the selected regions range from N sub(H)approximate 10 super(21) to10 super(23)cm super(-2), and hence they correspond to the bulk of the molecular clouds. The relative orientation is evaluated pixel by pixel and analysed in bins of column density using the novel statistical tool called "histogram of relative orientations". Throughout this study, we assume that the polarized emission observed by Planck at 353GHz is representative of the projected morphology of the magnetic field in each region, i.e., we assume a constant dust grain alignment efficiency, independent of the local environment. Within most clouds we find that the relative orientation changes progressively with increasing N sub(H), from mostly parallel or having no preferred orientation to mostly perpendicular. In simulations of magnetohydrodynamic turbulence in molecular clouds this trend in relative orientation is a signature of Alfvenic or sub-Alfvenic turbulence, implying that the magnetic field is significant for the gas dynamics at the scales probed by Planck. We compare the deduced magnetic field strength with estimates we obtain from other methods and discuss the implications of the Planck observations for the general picture of molecular cloud formation and evolution.
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